Trilosar 12.5mg Strip Of 10 Tablets
Description
Trilosar tablet is a combination medicine used to treat high blood pressure (hypertension). It contains losartan, amlodipine, and chlorthalidone, which together relax blood vessels, reduce excess fluid, and improve blood flow. By controlling blood pressure, this medicine helps reduce the risk of heart attack, stroke, and kidney damage. It is usually prescribed when a single medication is insufficient to control blood pressure effectively.
It works through three different mechanisms. Losartan blocks the action of angiotensin II, a hormone that tightens blood vessels and causes salt and water retention. Amlodipine relaxes and dilates blood vessels by blocking calcium influx into their smooth muscle, thereby improving blood flow. Chlorthalidone is a diuretic that helps the body eliminate excess salt and water through urine, reducing blood volume and lowering blood pressure. Together, they provide better, more sustained blood pressure control.
Take Trilosar tablet exactly as prescribed by your doctor. Swallow the tablet whole with a glass of water, preferably at the same time each day. It is best taken in the daytime and can be taken with or after food. Do not crush, chew, or break the tablet. If you miss a dose, take it as soon as you remember, unless it is almost time for your next dose. Do not double the dose to make up for a missed one.
Some people may experience side effects such as headache, dizziness, fatigue, nausea, flushing, swelling of the ankles or feet, abdominal pain, or diarrhoea. These effects are usually mild and improve as your body adjusts to the medicine. However, if you experience severe dizziness, low blood pressure, difficulty breathing, or facial or lip swelling, seek medical attention immediately. Always inform your doctor about any other medicines or supplements you are taking.
Product Summary
| Offer Price | ₹103.37 |
| You Save | ₹27.48 (21% on MRP) |
| Contains | Losartan(50.0 Mg)+Amlodipine(5.0 Mg)+Chlorthalidone / Chlortalidone(12.5 Mg) |
| Uses | hypertension (high blood pressure) |
| Side effects | dizziness, ankle swelling, headache, and electrolyte imbalances. |
| Therapy | ANTI-HYPERTENSIVE |
Uses
Contraindications
- If you are allergic to losartan, amlodipine, chlorthalidone, or any other ingredients of Trilosar tablet.
- If you are pregnant or planning to become pregnant.
- If you are breastfeeding, unless advised by your doctor.
- If you have very low urine output or severe kidney problems.
- If you have a history of severe liver disease.
- If you have low blood pressure or an electrolyte imbalance that your doctor has warned you about.
Side effects
- Headache
- Dizziness
- Fatigue
- Nausea
- Abdominal pain
- Diarrhoea
- Flushing
- Swelling of ankles or feet (edema)
- Weakness
- Low blood pressure
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
- You have kidney disease, have had a kidney transplant, or have liver disease.
- You have low blood pressure, dehydration, or recent excessive vomiting or diarrhoea.
- You have abnormal electrolyte levels, including sodium or potassium.
- You are taking potassium supplements or medicines that increase potassium levels in the body.
- You have heart problems, heart failure, or a history of stroke.
- You are pregnant, planning to become pregnant, or breastfeeding.
- You are taking other blood pressure medicines, lithium, NSAIDs, or aliskiren.
- You have gout or a history of elevated blood uric acid.
- You have any other chronic health condition or take multiple medications regularly.
Directions for Use
- Take Trilosar tablet exactly as prescribed by your doctor.
- Swallow it whole with a glass of water.
- It is best taken at a fixed time each day, preferably in the daytime.
- It can be taken with or after food.
- Do not crush, chew, or break the tablet.
Storage and disposal
- Store in a cool, dry place away from moisture and heat.
- Keep out of reach of children and pets.
- Do not use expired tablets.
Quick Tips
- Take Trilosar tablet at the same time every day for best results.
- Do not stop the medicine suddenly without medical advice.
- Maintain a healthy diet, exercise regularly, and limit salt intake.
- Monitor your blood pressure regularly.
- Stay hydrated, but avoid excess fluid intake unless advised.
- Avoid smoking and alcohol while on treatment.
Dosage
Overdose
Missed a Dose
- Take the missed dose as soon as you remember.
- If it is almost time for the next dose, skip the missed dose.
- Do not double the dose to make up for a missed one.
Mode of Action
How Does It Work?
- Losartan blocks angiotensin II, a hormone that tightens blood vessels and causes salt and water retention. This helps relax blood vessels and reduce fluid load.
- Amlodipine blocks calcium entry into blood vessel walls, thereby dilating blood vessels and improving blood flow.
- Chlorthalidone is a diuretic that increases the excretion of excess salt and water through urine, reducing blood volume and blood pressure.
- Together, they provide better and sustained blood pressure control.
Content Details
Ravindra Ghongade
B. Pharm
Dr. Nikita Toshi
BDS (Bachelor of Dental Surgery), WHO FIDES member
Frequently Asked Questions (FAQs)
Q: Can I stop taking Trilosar tablet if my blood pressure becomes normal?
Q: Does Trilosar tablet cause frequent urination?
Q: Is Trilosar tablet safe for long-term use?
Q: Can I take painkillers while using Trilosar tablet?
Q: What lifestyle changes should I follow while taking Trilosar tablet?
References
- Rwanda Food and Drugs Authority. Amlozaar Losartan Potassium 50 mg and Amlodipine 5 mg Tablets - Summary of Product Characteristics. Kigali: Rwanda FDA; 2024 Apr [cited 2025 Jan 12].
- Central Drugs Standard Control Organisation. Drugs. [Internet]. New Delhi: Directorate General of Health Services, Ministry of Health & Family Welfare, Government of India; [cited 2025 Jan 12].
- THALITONE [Internet]. Accessdata.fda.gov. 2025 [cited 12th Jan 2025]
- U.S. Food and Drug Administration. THALITONE® (chlorthalidone) Tablets USP 15 mg and 25 mg. FDA; 2018 2025 [cited 12th Jan 2025]
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