S Citadep Plus Tablet

• As per CDSCO, S Citadep Plus is used for
• Treatment of Comorbid Depression (depression associated with other disorders)
• Treatment of Anxiety Disorder

• If you are allergic to any active component of S Citadep Plus, i.e. Clonazepam, Escitalopram.
• If you are already taking Monoamine Oxidase Inhibitors (MAOIs)- linezolid, methylene blue, Selegiline, antipsychotic medicine-pimozide, anti-anxiety or sedative medications.
• If you are diagnosed with acute angle glaucoma (an eye condition that increases the fluid pressure in the eyes).
• If you have a seizure disorder and taking antiepileptic (anti-seizure) medications.
• If you have liver or kidney disease.
• If you have respiratory issues.
• If you have a severe heart condition.
• If you are pregnant or breastfeeding.

• Nausea
• Fatigue
• Confusion
• Drowsiness
• Increased Sweating
• Insomnia
• Sexual dysfunction

Other General Warnings

• You have any allergic reactions after taking S Citadep Plus.
• You experience sudden mood or behaviour changes.
• You experience recurrent suicidal ideation or self-harming thoughts.
• You notice a sudden loss of vision.
• You feel there is a worsening of the symptoms.
• You have trouble breathing or talking.
• If you have a mild or severe liver or kidney disease history, this medicine may need a dose adjustment.
• You are taking medication for other conditions or any health supplements.

• Take the S Citadep Plus Tablet as per the doctor’s prescription.
• S Citadep Plus can be taken with or without food or as prescribed. In case of any stomach illness, take it after meals.
• Take S Citadep Plus preferably at the same time every day to maintain its constant level in the body.
• Do not break/crush the tablet or chew this medicine; take it as a whole with a glass of water.
• Do not take S Citadep Plus with other medications; consult your doctor first.
• Don’t stop taking S Citadep Plus in between, as it may lead to withdrawal side effects.
• Don’t exceed the dosage on your own without consulting a doctor.

Overdose

Missed a Dose

How Does It Work?

Interactions with other medicines

• Avoid consuming S Citadep Plus with cola drinks, chocolates and caffeine-containing drinks like tea and coffee as it can result in serotonin syndrome (characterised by high blood pressure, confusion, and muscle rigidity). You should also avoid tyramine-rich beverages like cheese, milk, beef, chicken liver, meat extract, soybeans and grapefruit.

Interactions with food items

• Many medicines can interact with S Citadep Plus, making it less effective or increasing side effects. So, it is necessary to tell your doctor about all the prescription medicines you take.
• S Citadep Plus should not be used concomitantly or within two weeks of using Monoamine oxidase inhibitors (MAOIs) like isocarboxazid, linezolid, methylene blue, Selegiline, Rasagiline, etc. It is potentially life-threatening.
• Concomitant use of S Citadep Plus with antidepressant-like Clomipramine, Desipramine, Imipramine, Amitriptyline, Amoxapine, etc.; opioids and other CNS depressants is contraindicated, as it may cause respiratory depression, coma and death.
• S Citadep Plus Interaction with metoprolol can lead to excessive bradycardia (slow heart rate).
• S Citadep Plus interaction with antipsychotics (pimozide, haloperidol), tricyclic antidepressants and antihistamines can prolong QT interval on Ecg and may alter heart rhythm.
• S Citadep Plus interaction with NSAIDs, Aspirin, and other medications which affect coagulation can increase the risk of bleeding and bruises.
• S Citadep Plus may also interact with herbal medicine like St john’s wort can lead to life-threatening side effects.