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Rifabutin 150 Mg Tablet 10

10 Tablet(s) in Strip
We do not sell this product

Made by

LUPIN

Dosage

TABLET

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Product Summary

Salt Content
Rifabutin(150.0 Mg)
Uses
Pulmonary TB (only in patients co-infected with HIV; it should never be used as a substitute to Rifampicin in TB patients without HIV co-infection); H Pylori gastritis infection
Therapy
Anti-tubercular
Side effects
Nausea, Burping, Loose stools, Heartburn, Abdominal pain, Gastritis, Rash, Altered taste, Muscle pain
3 Step Quality
Assurance
Cash on delivery
available
NPPA
Regulated

Medical Description

Rifabutin 150 mg tablet is an antibiotic used with other medicines to help prevent or slow down the spread of Mycobacterium Avium Complex (MAC) disease and tuberculosis (TB) in HIV-positive persons. It is also used to treat H pylori infections that cause gastric ulcers. Rifabutin 150 mg tablet is also known as Rifamycin, an antimycobacterial medicine. The mode of action of Rifabutin 150 mg tablet is by killing the Mycobacteria species of bacteria. Rifabutin is a reserved antibiotic used specifically for the aforementioned conditions, as its undue use may develop resistance to treatment with this medicine. The directions for use of Rifabutin 150 mg tablets should be strictly followed. Side effects of Rifabutin 150 mg tablets include rashes, low haemoglobin, nausea, fever, heartburn/gastritis, loose stools, etc. These usually go away in a few days as the body adjusts to the medicines. The treating doctor must know the affected person’s medical history and all other medications being taken. This is so they can check for any potential interaction issues. Rifabutin 150 mg tablets give an orange-red colour to urine and all body fluids, including tears.

Uses

  • According to CDSCO guidelines, Rifabutin 150 mg tablets are used for:
  • Treatment of Pulmonary TB, only in patients co-infected with HIV. It should never be used as a substitute for Rifampicin in TB patients without HIV co-infection
  • Prevention of Mycobacterium Avium Complex (MAC) in persons co-infected with HIV
  • H Pylori gastritis infection

Contraindications

  • Do not take Rifabutin 150 mg tablets or use caution:
  • If you have chronic kidney disease; dose adjustment may be required
  • If you have severe liver disease; dose adjustment may be required
  • If you have an allergy to rifabutin, rifampin, rifaximin, other similar medicines; this medication is contraindicated in such cases

Side effects

  • Common side effects of Rifabutin 150 mg tablets include:
  • Nausea
  • Loose stools
  • Heartburn
  • Abdominal pain
  • Gastritis
  • Rash
  • Altered taste
  • Muscle pain
  • Discoloration of urine
  • Discoloration of skin

Precautions and Warnings

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Pregnancy

Limited human studies have not shown Rifabutin 150 mg tablets to harm the developing foetus. But, it cannot be concluded because animal data shows foetal anomalies. You need to confirm this with your doctor.

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Breast Feeding

Rifabutin 150 mg tablets are safe to use while breastfeeding. It is not known to cause harm to the baby. However, consult your doctor before taking any medicine while nursing your child.

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Driving

Yes. Rifabutin 150 mg tablets do not affect your ability to drive.

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Alcohol

No interaction is known of Rifabutin 150 mg tablet with alcohol. However, consult your doctor if you wish to drink alcohol while on treatment with Rifabutin 150 mg tablets.

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Other General Warnings

Talk to your doctor if
  • You have an allergy to rifabutin, rifampicin, rifaximin, other medicines, or any other ingredient in Rifabutin 150 mg tablets.
  • You have liver, heart, or kidney disease.
  • You take hormonal contraceptive pills or instruments; Rifabutin may interfere with the action of hormonal contraceptives. Talk to your doctor if you plan to conceive, become pregnant, or are breastfeeding while on treatment with Rifabutin 150 mg tablets.
  • You notice a change in the colour of your urine (orange-red), skin colour, or the colour of other body fluids.
  • You wear soft contact lenses.

Directions for Use

  • Take Rifabutin 150 mg tablets exactly as advised by your doctor.
  • Do not exceed the dosage, even if you cannot notice the effects of this medicine.
  • Take Rifabutin 150 mg tablets with a glass of water.
  • Take this medicine with food to minimise the side effects of nausea or vomiting.
  • Do not take Rifabutin 150 mg tablets with other medications without informing your doctor.
  • Do not consume this medicine if its packaging is broken.

Storage and disposal

Store Rifabutin 150 mg tablets at room temperature, away from wet surfaces, direct sunlight, and humidity. Keep away from children and pets. Check the expiration date before taking the tablets. Dispose of the packaging carefully after use. Do not flush extra or expired pills down the toilet.

Dosage

Overdose

Rifabutin 150 mg tablet overdose can cause severe reactions. If the affected person has collapsed, has breathing difficulty, or is unconscious, rush them to a nearby hospital for emergency treatment.

Missed a Dose

If you have missed a dose of Rifabutin 150 mg tablet, try to take it as soon as you remember. If you recall the missed dose when it is almost time for the next one, skip the missed one and continue with your regular dosing schedule. Do not take both of them together; this can lead to adverse reactions.

Mode of Action

How Does It Work?

Rifabutin 150 mg tablet is an antibiotic that kills and limits the growth of bacterial infection. It inhibits the DNA-dependent RNA polymerase enzyme in bacteria, which leads to decreased RNA synthesis, essential for the survival of the bacteria. This process ultimately leads to the death of the infection-causing bacteria.

Interactions

Interactions with other medicines

  • Rifabutin 150 mg tablets can interact with many medicines and cause adverse side effects. It is advised to inform the doctor of all medication being taken to be checked for possible interaction issues. The following medicines may become inactive or less effective if taken along with Rifabutin 150 mg tablets:
  • Antifungals like ketoconazole, itraconazole, fluconazole, and voriconazole
  • Antibiotics such as Ciprofloxacin
  • Antivirals such as Delavirdine
  • Macrolide antibiotics like clarithromycin
  • Hormonal contraceptives

Interactions with food items

  • Avoid taking Rifabutin 150 mg tablets with acidic food and beverages. These include sugar, dairy products, fish, fresh meat, sodas, processed foods, and sweetened beverages.

Frequently Asked Questions (FAQs)

Rifabutin 150 mg tablet is a longer-acting ant-TB antibiotic, having up to 35 hours of half-life. Rifampin, on the other hand, has a half-life of 3.5 hours. Both are used against the same bacteria and disease, but Rifabutin is more potent. Also, since TB bacteria have become resistant to Rifampin, Rifabutin is used instead.

This is not something you should be concerned about, as long as you have no other symptoms. Rifabutin 150 mg tablets cause an orange-red discolouration of the skin and body fluids like urine and tears. It is a side effect of this medicine and has nothing to do with blood loss or hematuria.

Do not stop taking this medicine even if you feel better. Anti-TB treatment takes 6-12 months to complete. Whether or not you have symptoms during this time, it is vital to finish the course of treatment. If you stop in between, the bacteria may become resistant to the antibiotic, and the disease will become harder to treat.

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Manufacturer Details

Brand:RIFABUTIN

Manufacturer Name:LUPIN

Address:<p>1. Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India</p>

Country of Origin:India

Vendor Details

Fulfillment Information: Rifabutin 150 MG Tablet (10) will be delivered by a licensed retail pharmacy nearest to your location. Order acceptance and fulfillment are dependent upon the verification of your doctor's valid prescription (where applicable) and the current stock of this medicine.

References:

In Case of Any Issues Contact Us

Email Id:care@pharmeasy.in

Phone Number:7666100300

Address:D-37/1, Opp. Sandoz, TTC Industrial Area, MIDC Industrial Area, Turbhe, Navi Mumbai, Maharashtra 400703

Disclaimer

The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here  for detailed T&C.

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