Placida Tablet
10 Tablet(s) in StripWe do not sell this product
Made by
MANKIND PHARMACEUTICALS LTD
Dosage
TABLET
Expiry
General Information
| Uses | Treatment of mild to moderate depression and anxiety |
| Therapy | Anti-depressant |
| Side effects | Drowsiness, dry mouth, constipation, vomiting, abdominal pain, nausea, flatulence, difficulty in breathing, myalgia, muscle rigidity, urinary retention, increased appetite, weight gain, and decreased libido. |
| Salt Content | Melitracen(10.0 Mg)+Flupentixol / Flupenthixol(0.5 Mg) |
Medicines
available
19k pincodes
Medical Description
Placida is a medication that contains a combination of two drugs, Flupentixol (0.5mg) and Melitracen (10mg), primarily used in the treatment of depression. Flupentixol belongs to a group of drugs called antipsychotics, whereas Melitracen is a tricyclic antidepressant. This combination at this particular dosage is used in the management of mild to moderate depression and anxiety.
Flupentixol is a first-generation antipsychotics. This drug works by blocking dopamine and serotonin receptors in the brain. At low doses (0.5- 3mg), this drug shows anti-depressant effects. It has also shown to decrease thoughts of self-harm in users who have such tendencies in depression.
Melitracen is a tricyclic antidepressant that acts on multiple brain pathways to increase levels of certain neurotransmitters, effectively decreasing the user’s symptoms. It acts by preventing the re-uptake of both serotonin as well as nor-adrenaline. It has both anti-depressant and anti-anxiety properties.
Placida should be taken as per the physician's recommendation only. It is best to take the tablet at the same time every day as this ensures the best action of the medication, decreasing the chances of relapse of symptoms significantly. It is also recommended to complete the entire course of the medication as prescribed.
Uses
- Mild to moderate depression
- Anxiety
- Asthenia (weakness)
Contraindications
- Patients with the following problems must refrain from consuming this medicine:
- Hypersensitivity
- Circulatory collapse
- Decreased level of consciousness due to any cause
- Coma
- Electroconvulsive therapy or severe depression requiring hospitalization
- Not recommended for use in manic or excited states.
- Patients with porphyrias (a kind of blood disorder where there is accumulation of a specific protein that is a byproduct of red blood cell metabolism)
- Epilepsy
- Patients with prolactin dependent tumors or breast cancer
- Parkinson's disease
- Narrow angle glaucoma
- Patients with prostate enlargement
- Thyroid disorders
- Cardiac disease or arrhythmias
- Severe respiratory disease
- Kidney failure
- Myasthenia gravis
- Pheochromocytoma
Side effects
- Drowsiness
- Dry mouth
- Increased appetite
- Weight gain
- Constipation
- Vomiting
- Acid regurgitation/ acid peptic disease
- Diarrhea
- Abdominal pain
- Nausea
- Flatulence
- Extra pyramidal effects, especially in the initial phase of the treatment, such as rigidity, muscle spasms, slowness of movements, tremors, irregular movements etc.
- Increased heart rate
- Palpitations
- Prolonged QT interval in ECG resulting in cardiac disorders like arrhythmias
- Hypotension (fall in blood pressure)
- Decrease in platelet, white blood cell counts
- Difficulty in breathing (dyspnea)
- Myalgia
- Muscle rigidity
- Retention of urine
- Poor control of blood sugar levels in case of diabetics
- Insomnia
- Decreased libido
- This drug is not recommended during pregnancy and breastfeeding.
- Close monitoring for changes in behavior, suicidal thoughts or clinical worsening during the initial part of the treatment is recommended. Withdrawal should be gradual
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
Talk to your doctor if
- Do not consume alcohol while on this medication.
- Driving and use of heavy machinery while on this medication is not recommended.
- Give your doctor details about any other medicine you are taking at the time of prescribing Placida.
Directions for Use
- This medication should be taken as prescribed by the treating physician.
- It is recommended to take this medication on a regular schedule, i.e., at the same time every day for optimal pharmacological effects of this medication.
- Swallow this medication as a whole. Do not crush, chew or break this tablet.
- It is recommended to finish the full course of this medication as prescribed by your treating doctor. Abrupt stoppage of the drug can cause withdrawal side effects. Consult your doctor before stopping this medication.
- It can be taken with or without food.
Storage and disposal
Keep in a cool and dry place.
Storage under 30’C
Quick Tips
- Do not stop this medicine suddenly, even if you feel better or feel it is not working. Stopping abruptly can cause nausea, headache, sleep disturbance and a return of symptoms. Your doctor will reduce it in steps.
- Allow time. Mood and anxiety symptoms usually take two to four weeks to improve, and the first change is often in sleep and appetite rather than mood.
- Report any new or worsening restlessness, agitation, or thoughts of self-harm to your doctor urgently, particularly in the first few weeks or after a dose change.
- Tell your doctor about any tremor, stiffness, slowness, restlessness in the legs, or involuntary movements of the face or tongue. The flupentixol component can cause movement-related effects that need acting on early.
- Avoid alcohol and be careful about driving. Drowsiness is common, especially at the start and after any increase.
- Take it at the same time each day as directed, and do not adjust the dose yourself if you feel it is not helping - tell your doctor instead.
- Tell your doctor if you have heart disease, a heart rhythm problem, glaucoma, difficulty passing urine, epilepsy, liver disease, or are pregnant or breastfeeding.
- Keep only what you need at home and store it out of reach. Melitracen belongs to the tricyclic group, which is dangerous in overdose and affects the heart rhythm, so an accidental or deliberate overdose is a medical emergency even if the person seems alert at first.
Dosage
Overdose
Overdose is characterized by extreme agitation, excitement, confusion, sleepiness, coma, convulsions, and hyperthermia or hypothermia, frequently succeeded by sedation. Extrapyramidal symptoms or respiratory and circulatory collapse may be observed. QT prolongation, ECG changes, cardiac arrest, and ventricular arrhythmias have been reported with large doses of Flupentixol. In case of overdose, symptomatic treatment should be initiated with airway management. In case of a suspected overdose, immediately rush the patient to the nearest medical centre for emergency management as it can be life threatening.
Missed a Dose
If you miss a dose of this tablet, it is advised to take it as soon as possible. If the duration missed is too long, and it is almost time for the next dose, it is recommended to skip the missed dose and go back to the regular schedule. Do not double the dose of the tablet.
Interactions
Interactions with other drugs
Interactions with food items
- It is known to cause an increase in appetite and weight gain, and is thus recommended to consume a healthy, balanced diet.
Frequently Asked Questions (FAQs)
References:
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Manufacturer Details
Brand:PLACIDA
Manufacturer Name:MANKIND PHARMACEUTICALS LTD
Address:J.K.Print Packs (Pharma Division), C-14 To 17, Sara Industrial Estate Ltd. Vill Rampur, Selaqui, Distt. Dehradun 248197, Uttarakhand
Country of Origin:India
Vendor Details
Fulfillment Information: Placida Strip Of 10 Tablets will be delivered by a licensed retail pharmacy nearest to your location. Order acceptance and fulfillment are dependent upon the verification of your doctor's valid prescription (where applicable) and the current stock of this medicine.
In Case of Any Issues Contact Us
Email Id:care@pharmeasy.in
Phone Number:7666100300
Address:D-37/1, Opp. Sandoz, TTC Industrial Area, MIDC Industrial Area, Turbhe, Navi Mumbai, Maharashtra 400703
Disclaimer
The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here  for detailed T&C.
