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Placida Strip Of 10 Tablets

10 Tablet(s) in Strip
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Placida Strip Of 10 Tablets Description

Placida is a medication that contains a combination of two drugs, Flupentixol (0.5mg) and Melitracen (10mg), primarily used in the treatment of depression. Flupentixol belongs to a group of drugs cal

led antipsychotics, whereas Melitracen is a tricyclic antidepressant. This combination at this particular dosage is used in the management of mild to moderate depression and anxiety. Flupentixol is a first-generation antipsychotics. This drug works by blocking dopamine and serotonin receptors in the brain. At low doses (0.5- 3mg), this drug shows anti-depressant effects. It has also shown to decrease thoughts of self-harm in users who have such tendencies in depression. Melitracen is a tricyclic antidepressant that acts on multiple brain pathways to increase levels of certain neurotransmitters, effectively decreasing the user’s symptoms. It acts by preventing the re-uptake of both serotonin as well as nor-adrenaline. It has both anti-depressant and anti-anxiety properties. Placida should be taken as per the physician's recommendation only. It is best to take the tablet at the same time every day as this ensures the best action of the medication, decreasing the chances of relapse of symptoms significantly. It is also recommended to complete the entire course of the medication as prescribed.


Product Summary

Offer Price₹61.22
You Save₹8.35 (12% on MRP)
ContainsMelitracen(10.0 Mg) + Flupentixol / Flupenthixol(0.5 Mg)
UsesTreatment of mild to moderate depression and anxiety
Side effectsDrowsiness, dry mouth, constipation, vomiting, abdominal pain, nausea, flatulence, difficulty in breathing, myalgia, muscle rigidity, urinary retention, increased appetite, weight gain, and decreased libido.
Check more medicines with composition as Melitracen(10.0 Mg) + Flupentixol / Flupenthixol(0.5 Mg)

Uses of Placida Strip Of 10 Tablets

  • Mild to moderate depression
  • Anxiety
  • Asthenia (weakness)

Contraindications of Placida Strip Of 10 Tablets

  • Patients with the following problems must refrain from consuming this medicine:
  • Hypersensitivity
  • Circulatory collapse
  • Decreased level of consciousness due to any cause
  • Coma
  • Electroconvulsive therapy or severe depression requiring hospitalization
  • Not recommended for use in manic or excited states.
  • Patients with porphyrias (a kind of blood disorder where there is accumulation of a specific protein that is a byproduct of red blood cell metabolism)
  • Epilepsy
  • Patients with prolactin dependent tumors or breast cancer
  • Parkinson's disease
  • Narrow angle glaucoma
  • Patients with prostate enlargement
  • Thyroid disorders
  • Cardiac disease or arrhythmias
  • Severe respiratory disease
  • Kidney failure
  • Myasthenia gravis
  • Pheochromocytoma

Side effects of Placida Strip Of 10 Tablets

  • Drowsiness
  • Dry mouth
  • Increased appetite
  • Weight gain
  • Constipation
  • Vomiting
  • Acid regurgitation/ acid peptic disease
  • Diarrhea
  • Abdominal pain
  • Nausea
  • Flatulence
  • Extra pyramidal effects, especially in the initial phase of the treatment, such as rigidity, muscle spasms, slowness of movements, tremors, irregular movements etc.
  • Increased heart rate
  • Palpitations
  • Prolonged QT interval in ECG resulting in cardiac disorders like arrhythmias
  • Hypotension (fall in blood pressure)
  • Decrease in platelet, white blood cell counts
  • Difficulty in breathing (dyspnea)
  • Myalgia
  • Muscle rigidity
  • Retention of urine
  • Poor control of blood sugar levels in case of diabetics
  • Insomnia
  • Decreased libido
  • This drug is not recommended during pregnancy and breastfeeding.
  • Close monitoring for changes in behavior, suicidal thoughts or clinical worsening during the initial part of the treatment is recommended. Withdrawal should be gradual

Precautions and Warnings of Placida Strip Of 10 Tablets



Can I take Placida during pregnancy?
This drug is not recommended during pregnancy. Inform your doctor regarding your pregnancy or your intention to conceive. Discuss with your treating physician regarding the requirement of this medication if it is prescribed

Breast Feeding

Can I take Placida while breastfeeding?
This medication is generally not advised while breastfeeding. Discuss your breastfeeding status with your doctor for more information.


Can I drive if I have taken Placida?
Driving and operating of other heavy machinery while on this medication is not recommended as it may cause drowsiness and blurring of vision.


Can I consume alcohol with the Placida?
You must refrain from alcohol consumption while on this medication as mixing alcohol with this medication may cause increased sedation and other adverse effects.

Other General Warnings

Talk to your doctor if
  • Do not consume alcohol while on this medication.
  • Driving and use of heavy machinery while on this medication is not recommended.
  • Give your doctor details about any other medicine you are taking at the time of prescribing Placida.

Mode of Action of Placida Strip Of 10 Tablets

How Does It Work?

Flupentixol belongs to a class of drugs known as first-generation antipsychotics. At lower doses (between 0.5mg to 3mg), it is known to exert antidepressant effects, particularly in combination with M...
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Directions for Use of Placida Strip Of 10 Tablets

  • This medication should be taken as prescribed by the treating physician.
  • It is recommended to take this medication on a regular schedule, i.e., at the same time every day for optimal pharmacological effects of this medication.
  • Swallow this medication as a whole. Do not crush, chew or break this tablet.
  • It is recommended to finish the full course of this medication as prescribed by your treating doctor. Abrupt stoppage of the drug can cause withdrawal side effects. Consult your doctor before stopping...
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  • It can be taken with or without food.

Interactions of Placida Strip Of 10 Tablets

Interactions with other medicines

  • This medication is known to potentiate the effects of general anesthetics.
  • This medication should not be mixed with anticoagulants, such as heparin, warfarin, rivaroxaban, dabigatran, apixaban etc as it may increase their effects beyond therapeutic benefits.
  • This medication can prolong the action of neuromuscular blockers, such as vecuronium, rocuronium, succinylcholine.
  • May increase anticholinergic effects of drugs with anticholinergic activity and atropine. Anticholinergic effects include dry mouth, constipation, urinary retention, bowel obstruction, dilated pupils,...
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  • May increase risk of neurotoxicity when consumed with lithium or sibutramine.
  • Avoid concurrent usage with drugs that cause QT prolongation or cardiac arrhythmias.
  • Do not mix this medication with other tricyclic antidepressants as it may affect metabolism.

Interactions with food items

  • It is known to cause an increase in appetite and weight gain, and is thus recommended to consume a healthy, balanced diet.

Storage and disposal of Placida Strip Of 10 Tablets

Keep in a cool and dry place. Storage under 30’C

Dosage of Placida Strip Of 10 Tablets


Overdose is characterized by extreme agitation, excitement, confusion, sleepiness, coma, convulsions, and hyperthermia or hypothermia, frequently succeeded by sedation. Extrapyramidal symptoms or resp...
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Missed a Dose

If you miss a dose of this tablet, it is advised to take it as soon as possible. If the duration missed is too long, and it is almost time for the next dose, it is recommended to skip the missed dose ...
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Content Details


Dr. Bhavika Shah

MBBS, MD (Dermatology), DNB (Dermatology)

Frequently Asked Questions (FAQs)


Q: I have been using Placida for 2 weeks now. I feel it is not helping me. Can I increase the dose?

A: This medication is known to take up to 4-6 weeks for onset of action. Consult your treating physician regarding any queries regarding the use of this medication. It is not advisable to increase the dose of this medication on your own without the recommendation of your doctor.

Q: I feel drowsy ever since I have started this medication. My weight has also increased. Should I stop the tablet?

A: Weight gain and drowsiness are common side effects of Placida. Your doctor can guide you on how to manage these symptoms. Please continue taking the tablet as advised until you consult your doctor.

Q: Can I drink alcohol occasionally while taking the tablet? I am not a regular drinker.

A: No. Even occasional consumption of alcohol can be dangerous and should be avoided.
Product Details
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Last Updated on: 20 Jan 2022 | 11:18 AM (IST)

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The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here  for detailed T&C.
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