Placida Strip Of 10 Tablets

By MANKIND PHARMACEUTICALS LTD

10 Tablet(s) in Strip

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Placida Strip Of 10 Tablets Description

Placida is a medication that contains a combination of two drugs, Flupentixol (0.5mg) and Melitracen (10mg), primarily used in the treatment of depression. Flupentixol belongs to a group of drugs cal

led antipsychotics, whereas Melitracen is a tricyclic antidepressant. This combination at this particular dosage is used in the management of mild to moderate depression and anxiety. Flupentixol is a first-generation antipsychotics. This drug works by blocking dopamine and serotonin receptors in the brain. At low doses (0.5- 3mg), this drug shows anti-depressant effects. It has also shown to decrease thoughts of self-harm in users who have such tendencies in depression. Melitracen is a tricyclic antidepressant that acts on multiple brain pathways to increase levels of certain neurotransmitters, effectively decreasing the user’s symptoms. It acts by preventing the re-uptake of both serotonin as well as nor-adrenaline. It has both anti-depressant and anti-anxiety properties. Placida should be taken as per the physician's recommendation only. It is best to take the tablet at the same time every day as this ensures the best action of the medication, decreasing the chances of relapse of symptoms significantly. It is also recommended to complete the entire course of the medication as prescribed.

Product Summary

Offer Price	₹59.83
You Save	₹9.74 (14% on MRP)
Contains	Melitracen(10.0 Mg) + Flupentixol / Flupenthixol(0.5 Mg)
Uses	Treatment of mild to moderate depression and anxiety
Side effects	Drowsiness, dry mouth, constipation, vomiting, abdominal pain, nausea, flatulence, difficulty in breathing, myalgia, muscle rigidity, urinary retention, increased appetite, weight gain, and decreased libido.
Therapy	ANTI-DEPRESSANT

Check more medicines with composition as Melitracen(10.0 Mg) + Flupentixol / Flupenthixol(0.5 Mg)

Precautions and Warnings

Uses of Placida Strip Of 10 Tablets

Mild to moderate depression
Anxiety
Asthenia (weakness)

Contraindications of Placida Strip Of 10 Tablets

Patients with the following problems must refrain from consuming this medicine:
Hypersensitivity
Circulatory collapse
Decreased level of consciousness due to any cause
Coma
Electroconvulsive therapy or severe depression requiring hospitalization
Not recommended for use in manic or excited states.
Patients with porphyrias (a kind of blood disorder where there is accumulation of a specific protein that is a byproduct of red blood cell metabolism)
Epilepsy
Patients with prolactin dependent tumors or breast cancer
Parkinson's disease
Narrow angle glaucoma
Patients with prostate enlargement
Thyroid disorders
Cardiac disease or arrhythmias
Severe respiratory disease
Kidney failure
Myasthenia gravis
Pheochromocytoma

Side effects of Placida Strip Of 10 Tablets

Drowsiness
Dry mouth
Increased appetite
Weight gain
Constipation
Vomiting
Acid regurgitation/ acid peptic disease
Diarrhea
Abdominal pain
Nausea
Flatulence
Extra pyramidal effects, especially in the initial phase of the treatment, such as rigidity, muscle spasms, slowness of movements, tremors, irregular movements etc.
Increased heart rate
Palpitations
Prolonged QT interval in ECG resulting in cardiac disorders like arrhythmias
Hypotension (fall in blood pressure)
Decrease in platelet, white blood cell counts
Difficulty in breathing (dyspnea)
Myalgia
Muscle rigidity
Retention of urine
Poor control of blood sugar levels in case of diabetics
Insomnia
Decreased libido
This drug is not recommended during pregnancy and breastfeeding.
Close monitoring for changes in behavior, suicidal thoughts or clinical worsening during the initial part of the treatment is recommended. Withdrawal should be gradual

Precautions and Warnings of Placida Strip Of 10 Tablets

Pregnancy

Can I take Placida during pregnancy?

This drug is not recommended during pregnancy. Inform your doctor regarding your pregnancy or your intention to conceive. Discuss with your treating physician regarding the requirement of this medication if it is prescribed

Breast Feeding

Can I take Placida while breastfeeding?

This medication is generally not advised while breastfeeding. Discuss your breastfeeding status with your doctor for more information.

Driving

Can I drive if I have taken Placida?

Driving and operating of other heavy machinery while on this medication is not recommended as it may cause drowsiness and blurring of vision.

Alcohol

Can I consume alcohol with the Placida?

You must refrain from alcohol consumption while on this medication as mixing alcohol with this medication may cause increased sedation and other adverse effects.

Other General Warnings

Talk to your doctor if

Do not consume alcohol while on this medication.
Driving and use of heavy machinery while on this medication is not recommended.
Give your doctor details about any other medicine you are taking at the time of prescribing Placida.

Mode of Action of Placida Strip Of 10 Tablets

How Does It Work?

Flupentixol belongs to a class of drugs known as first-generation antipsychotics. At lower doses (between 0.5mg to 3mg), it is known to exert antidepressant effects, particularly in combination with M...

Directions for Use of Placida Strip Of 10 Tablets

This medication should be taken as prescribed by the treating physician.
It is recommended to take this medication on a regular schedule, i.e., at the same time every day for optimal pharmacological effects of this medication.
Swallow this medication as a whole. Do not crush, chew or break this tablet.
It is recommended to finish the full course of this medication as prescribed by your treating doctor. Abrupt stoppage of the drug can cause withdrawal side effects. Consult your doctor before stopping...
Read more
It can be taken with or without food.

Interactions of Placida Strip Of 10 Tablets

Interactions with other medicines

This medication is known to potentiate the effects of general anesthetics.
This medication should not be mixed with anticoagulants, such as heparin, warfarin, rivaroxaban, dabigatran, apixaban etc as it may increase their effects beyond therapeutic benefits.
This medication can prolong the action of neuromuscular blockers, such as vecuronium, rocuronium, succinylcholine.
May increase anticholinergic effects of drugs with anticholinergic activity and atropine. Anticholinergic effects include dry mouth, constipation, urinary retention, bowel obstruction, dilated pupils,...
Read more
May increase risk of neurotoxicity when consumed with lithium or sibutramine.
Avoid concurrent usage with drugs that cause QT prolongation or cardiac arrhythmias.
Do not mix this medication with other tricyclic antidepressants as it may affect metabolism.

Interactions with food items

It is known to cause an increase in appetite and weight gain, and is thus recommended to consume a healthy, balanced diet.

Storage and disposal of Placida Strip Of 10 Tablets

Keep in a cool and dry place. Storage under 30’C

Dosage of Placida Strip Of 10 Tablets

Overdose

Overdose is characterized by extreme agitation, excitement, confusion, sleepiness, coma, convulsions, and hyperthermia or hypothermia, frequently succeeded by sedation. Extrapyramidal symptoms or resp...

Missed a Dose

If you miss a dose of this tablet, it is advised to take it as soon as possible. If the duration missed is too long, and it is almost time for the next dose, it is recommended to skip the missed dose ...

Content Details

WRITTEN BY

Dr. Adithya Padmanabhan V

MBBS

REVIEWED BY

Dr. Bhavika Shah

MBBS, MD (Dermatology), DNB (Dermatology)

Frequently Asked Questions (FAQs)

Q: I have been using Placida for 2 weeks now. I feel it is not helping me. Can I increase the dose?

A: This medication is known to take up to 4-6 weeks for onset of action. Consult your treating physician regarding any queries regarding the use of this medication. It is not advisable to increase the dose of this medication on your own without the recommendation of your doctor.

Q: I feel drowsy ever since I have started this medication. My weight has also increased. Should I stop the tablet?

A: Weight gain and drowsiness are common side effects of Placida. Your doctor can guide you on how to manage these symptoms. Please continue taking the tablet as advised until you consult your doctor.

Q: Can I drink alcohol occasionally while taking the tablet? I am not a regular drinker.

A: No. Even occasional consumption of alcohol can be dangerous and should be avoided.

References

Product Details

Brand

PLACIDA

Expires on or After

30/07/2023

Manufacturer Details

Other Products from this Brand

PLACIDA PLUS STRIP OF 10 TABLETS

Last Updated on: 20 Jan 2022 | 11:18 AM (IST)

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