Linezolid
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Molecule Summary
| Uses | Bacterial Infections |
| Therapy | Unsure |
| Side Effects | Nausea, Vomiting, Diarrhoea, Headache, Low Blood Cell Counts |
Assurance
available
Regulated
Molecule Description
Linezolid is an antibiotic of the Oxazolidinones group that works by stopping the growth of certain bacteria that cause infections.
Uses
- Pneumonia
- Skin infections
- Bacterial infections as per doctor’s discretion
Contraindications
When should one not use Linezolid
- If you are allergic to Linezolid
- If you are taking medicines called Monoamine Oxidase Inhibitors (MAOI) like Phenelzine, Isocarboxazid, Selegiline, Moclobemide or have taken these within the last two weeks
- If you are breastfeeding
- Kidney or liver disease
Side effects
Common side effects of this drug are:
- Nausea, vomiting
- Stomach pain
- Diarrhea - bloody or watery
- Vaginal itching or discharge
- Constipation
- Headache, dizziness
- Skin rash, itching
- Allergy – facial swelling, difficulty in breathing (serious)
- Anemia
- Vision disturbances- blurred vision, change in colour vision
- Bleeding from nose, mouth, etc.
- Easy bruising
- Fits (uncommon)
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
Talk to your doctor if
- You have bruise and bleed easily
- You are anaemic
- You have a history of fits
- You have liver problems or kidney problems or undergoing dialysis
- You have diarrhoea
- Visual disturbances like blurred vision, changes in colour vision, difficulty in seeing detail or if your field of view becomes restricted
- If you develop diarrhea while taking Linezolid. If this becomes persistent or you notice blood or mucus in stools, immediately stop taking Linezolid and consult your doctor
Mode of Action
How Does It Work?
Linezolid controls infection by killing the bacteria.
Interactions
Interactions with other medicines
Tell your doctor if you are taking or have taken within the last two weeks the following medicines: Monoamine Oxidase Inhibitors ( MAOIs, e.g. Phenelzine, Isocarboxazid, Selegiline, Moclobemide). These may be used to treat depression or Parkinson’s disease, glaucoma medicines, medicines that can raise blood pressure, e.g., Levodopa or diet pills, stimulants, or ADHD medications, cough or cold medication (Pseudoephedrine or Phenylpropanolamine) and Rifampicin, certain antidepressants known as Tricyclics or SSRIs (Selective Serotonin Reuptake Inhibitors). There are many of these including Amitriptyline, Citalopram, Clomipramine, Dosulepin, Doxepin, Fluoxetine, Fluvoxamine, Imipramine, Lofepramine, Paroxetine, Sertralin.
Interactions with food items
Avoid eating large amounts of cheese, yeast extracts or soya bean extracts e.g. soy sauce. It is because Linezolid may react with a substance called Tyramine which is naturally present in some foods. This interaction may cause an increase in your blood pressure.
Dosage
Overdose
If you happen to take an overdose of the medicine, kindly seek emergency medical care immediately. The effects of an overdose may be lethal and need immediate medical attention. Overdose symptoms may be – nose or mouth bleeding, etc. easy bruising, vertigo, etc.
Missed a Dose
Take the forgotten tablet as early as you remember. Take the next pill 12 hours after this and continue taking your tablets every 12 hours.
Frequently Asked Questions (FAQs)
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