Ibuprofen
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Molecule Description
Ibuprofen is a medicine classified as a Non-Steroidal Anti-Inflammatory Drug (NSAID). It is commonly used to relieve pain, reduce inflammation, and lower fever. It works by blocking chemicals in the body that cause pain and swelling. Ibuprofen should be taken exactly as directed by your doctor or as indicated on the label to minimise the risk of side effects, such as stomach upset or irritation.
Uses
- It is used in the treatment of rheumatic and muscular pain, backache, headache, dental pain, migraine, neuralgia and periods pain
- It can also provide relief in fever and the symptoms of colds and flu
Contraindications
When should one not use Ibuprofen
- If you have a stomach ulcer or bleeding
- If you are allergic to Ibuprofen or any ingredient of this medicine
- If you have severe kidney, heart or liver disorder
Side effects
Common side effects of this drug are:
- Stomach pain
- Allergic reactions like rashes
- Stomach pain, heartburn, indigestion
- Diarrhea, flatulence
- Nausea
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
Talk to your doctor if
- You have heart problems including heart failure, angina
- You have high blood pressure, diabetes, high cholesterol or you smoke
- You have asthma, allergic reactions
- You are in the age group of 12-18 years
Mode of Action
How Does It Work?
Ibuprofen acts by hindering the release of certain chemical substances in the body, which cause pain or swelling.
Interactions
Interactions with other medicines
- Blood thinners like Warfarin
- Medicines used to treat high blood pressure like Captopril, beta-blockers such as Atenolol
- Antiplatelet agents, cardiac glycosides, selective Serotonin Reuptake Inhibitors, Lithium, Methotrexate, Ciclosporin, Mifepristone, Tacrolimus, Zidovudine or Quinolone antibiotics
Interactions with food items
No known food interaction has been reported.
Dosage
Overdose
Symptoms of overdose include nausea, stomach pain, vomiting, headache, ringing in the ears and confusion. At high dosages, drowsiness, chest pain, palpitations, loss of consciousness, convulsions (mainly in children), weakness and dizziness, blood in urine, cold body feeling and breathing problems can occur. If you think you have taken too much Ibuprofen, contact your doctor immediately or visit the nearest hospital.
Missed a Dose
Do not take a double dose if you have missed the dose; take the next dose as soon as you remember.
Frequently Asked Questions (FAQs)
Articles
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References:
- Anadin. Ibuprofen – Patient Information Leaflet [Internet]. London: electronic Medicines Compendium (emc); [cited 2025 Sep 16].
- WebMD LLC. Ibuprofen (oral) [Internet]. [cited 2025 Sep 16].
- Amneal Pharmaceuticals of New York LLC. Ibuprofen (NSAID) Pain Reliever/Fever Reducer – Drug Label Information [Internet]. Bethesda (MD): U.S. National Library of Medicine; [cited 2025 Sep 16].
- National Institute of Child Health and Human Development. Ibuprofen [Internet]. In: Drugs and Lactation Database (LactMed®). Bethesda (MD): National Library of Medicine; [cited 2025 Sep 16].
- Central Drugs Standard Control Organization. Drugs [Internet]. New Delhi: Directorate General of Health Services, Ministry of Health & Family Welfare, Government of India; [cited 2025 Sep 16].
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