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Ibuprofen

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Molecule Description

Ibuprofen is a medicine classified as a Non-Steroidal Anti-Inflammatory Drug (NSAID). It is commonly used to relieve pain, reduce inflammation, and lower fever. It works by blocking chemicals in the body that cause pain and swelling. Ibuprofen should be taken exactly as directed by your doctor or as indicated on the label to minimise the risk of side effects, such as stomach upset or irritation.

Uses

  • It is used in the treatment of rheumatic and muscular pain, backache, headache, dental pain, migraine, neuralgia and periods pain
  • It can also provide relief in fever and the symptoms of colds and flu

Contraindications

When should one not use Ibuprofen

  • If you have a stomach ulcer or bleeding
  • If you are allergic to Ibuprofen or any ingredient of this medicine
  • If you have severe kidney, heart or liver disorder

Side effects

Common side effects of this drug are:

  • Stomach pain
  • Allergic reactions like rashes
  • Stomach pain, heartburn, indigestion
  • Diarrhea, flatulence
  • Nausea

Precautions and Warnings

Pregnancy

Pregnancy

It is not safe during pregnancy, especially in the last three months of pregnancy. You should consult with the doctor as he/ she will tell you about the usage of Ibuprofen after assessing the benefits over risks.

Breast Feeding

Breast Feeding

It is advised to consult a doctor, especially in the first six months of breastfeeding. It passes into the mother’s milk in small amounts, so it may affect the newborn baby.

Driving

Driving

It does not usually affect your ability to drive.

Alcohol

Alcohol

Ibuprofen should not be taken with alcohol. It increases the side effects like dizziness and difficulty in concentration. It also causes severe stomach pain.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You have heart problems including heart failure, angina
  • You have high blood pressure, diabetes, high cholesterol or you smoke
  • You have asthma, allergic reactions
  • You are in the age group of 12-18 years

Mode of Action

How Does It Work?

Ibuprofen acts by hindering the release of certain chemical substances in the body, which cause pain or swelling.

Interactions

Interactions with other medicines

  • Blood thinners like Warfarin
  • Medicines used to treat high blood pressure like Captopril, beta-blockers such as Atenolol
  • Antiplatelet agents, cardiac glycosides, selective Serotonin Reuptake Inhibitors, Lithium, Methotrexate, Ciclosporin, Mifepristone, Tacrolimus, Zidovudine or Quinolone antibiotics

Interactions with food items

No known food interaction has been reported.

Dosage

Overdose

Symptoms of overdose include nausea, stomach pain, vomiting, headache, ringing in the ears and confusion. At high dosages, drowsiness, chest pain, palpitations, loss of consciousness, convulsions (mainly in children), weakness and dizziness, blood in urine, cold body feeling and breathing problems can occur. If you think you have taken too much Ibuprofen, contact your doctor immediately or visit the nearest hospital.

Missed a Dose

Do not take a double dose if you have missed the dose; take the next dose as soon as you remember.

Frequently Asked Questions (FAQs)

Give a detailed account of your medical and surgical history. The doctor should know if you have an allergy, asthma, stomach ulcers or are pregnant.

The dosage regimen of the drug should be followed regularly. Do not use this drug for an extended period. It is known to be toxic to the kidney on prolonged use.

Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) used to relieve pain, reduce inflammation, and lower fever. It is commonly used to treat headaches, muscle pain, joint pain, menstrual cramps, toothaches, arthritis, and injuries. It helps make daily activities more comfortable by reducing swelling and pain.

Ibuprofen works by blocking certain chemicals in the body called prostaglandins, which are responsible for causing pain, inflammation, and fever. By reducing prostaglandins, Ibuprofen lowers pain and swelling, helping the body feel more comfortable.

Common side effects include stomach pain, heartburn, nausea, mild headache, or dizziness. Rare but serious side effects include stomach ulcers, bleeding, kidney problems, high blood pressure, or allergic reactions. Seek immediate medical help if you notice severe stomach pain, black stools, swelling, or shortness of breath.

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