Open Up 300mg Strip Of 10 Tablets
Open Up 300 MG Description
Open Up Tablet is used to dissolve gallstones in various liver-related disorders such as cirrhosis, sclerosing cholangitis and liver dysfunction. Open Up Tablet contains ursodeoxycholic acid as its a
ctive ingredient. Gallstones are hardened deposits of digestive juices formed in the gall bladder (a small organ found under the liver). It mainly occurs due to increased cholesterol content in bile juice. Open Up Tablet acts as a dissolving agent, which reduces the cholesterol content in bile. Take this medicine as advised by your treating doctor, for the prescribed duration.
Product Summary
Offer Price | ₹341.88 |
You Save | ₹29.73 (8% on MRP) |
Contains | Ursodeoxycholic Acid / Ursodiol(300.0 Mg) |
Uses | Gallbladder stones and Liver dysfunction |
Side effects | Nausea, vomiting, diarrhoea, sticky stool |
Therapy | DRUGS FOR CHOLELITHIASIS |
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Uses of Open Up 300 MG
- Open Up Tablet is used to dissolve gallbladder stones that are made of cholesterol in various liver-related disorders such as cirrhosis and sclerosing cholangitis.
- Liver dysfunction is associated with cystic fibrosis (a hereditary disease that affects the lungs and digestive system).
Contraindications of Open Up 300 MG
- If you are allergic to ursodeoxycholic acid or any ingredient of Open Up Tablet.
- If you have stomach or intestinal ulcer or bleeding.
- If you have recently had surgery involving any part of your intestine.
- If you have a liver-related disorder and non-functional gall bladder.
- If you are suffering from a liver or intestinal condition which affects the circulation of bile substances like blockage of the bile duct.
- If you are suffering from inflammation/blockage of the gall bladder or biliary tract.
Side effects of Open Up 300 MG
- Nausea
- Vomiting
- Diarrhoea
- Sticky stool
Precautions and Warnings of Open Up 300 MG
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
- You have a history of liver disease or obstruction in bile passage, your doctor may ask you to do a liver function test regularly.
- You experience a persistent diarrhoea, your doctor may discontinue the therapy immediately.
- Women of childbearing age should use non-hormonal contraceptive measures (physical barrier) or low oestrogen oral contraceptive pills. Combination oral contraceptive pills should not be taken with Open Up....
- Your doctor may ask you for an ultrasound after six months of the treatment to check the therapeutic improvement.
- It would be best if you avoided a high cholesterol diet during the treatment as it may affect the effectiveness of Open Up.
Mode of Action of Open Up 300 MG
How Does It Work?
Directions for Use of Open Up 300 MG
- Open Up Tablet should be taken as directed by your doctor. Swallow it whole with a glass of water. Do not cut, break or chew the medicine.
- It should be taken after having your meal. It would be best if you took it at a fixed time for optimal results.
- You should not consume it more than that prescribed by your doctor.
Interactions of Open Up 300 MG
Interactions with other medicines
- Open Up Tablet may interact with other medications and provide an altered response to the treatment. Please notify your doctor if you are undergoing any other treatments, over-the-counter medications (that you buy without a prescription) and herbal preparations. Also, you should inform your doctor if you have a planned surgery or vaccination scheduled....
- Hormonal pills should not be used if you are on treatment with Open Up Tablets.
- Concomitant use of cholesterol-lowering medicines like cholestyramine or colestipol and some antacids may reduce the efficacy of Open Up. So, it should be taken between the gap of 2 hours at least.
- Other medicines that may affect this tablet's absorption are charcoal and antibiotics like Ciprofloxacin, immunosuppressants like Ciclosporin, cholesterol-lowering medicines like Atorvastatin and Dapsone used as an anti-infective. Hence, it should not be used concomitantly....
Interactions with food items
Storage and disposal of Open Up 300 MG
- Store Open Up Tablets in a cool and dry place, protected from direct sunlight, moisture and heat.
- Keep it away from children and pets.
- Discard any unused and expired medicine properly. Do not flush in the toilet or throw it into the drain.
Dosage of Open Up 300 MG
Overdose
Missed a Dose
Content Details
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Dr. Mansi Savla
B. Pharm, PharmD

Dr. Ritu Budania
MBBS, MD (Pharmacology)
Frequently Asked Questions (FAQs)
Q: Can Open Up reduce raised liver enzymes?
Q: Does high blood cholesterol level cause gallbladder stones?
Q: What is Open Up Tablet used for?
- Open Up Tablet is used to dissolve gallbladder stones that are made of cholesterol in various liver-related disorders such as cirrhosis and sclerosing cholangitis.
- It is also used in liver dysfunction associated with cystic fibrosis (a hereditary disease that affects the lungs and digestive system).
References
- DESTOLIT 150 mg tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2022 [cited 9 May 2022]
- CDSCO - Ursodeoxycholic acid [Internet]. Cdscoonline.gov.in. 2022 [cited 9 May 2022]
- URSO (ursodiol) tablets, for oral use, USP, [Internet]. Accessdata.fda.gov. 2022 [cited 9 May 2022]
- Lactmed - Ursodiol [Internet]. Ncbi.nlm.nih.gov. 2022 [cited 9 May 2022]
- DESTOLIT 150 mg tablets - Patient Information Leaflet (PIL) - (emc) [Internet]. Medicines.org.uk. 2022 [cited 9 May 2022]
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