Nexbolic Injection Vet
Description
Nexbolic injection is used to control heavy bleeding from the uterus during childbirth, especially after the baby’s shoulder is delivered. It contains methylergometrine as an active ingredient. It works by helping your uterus tighten and contract strongly, which in turn squeezes the blood vessels and helps stop the bleeding. It also slightly narrows blood vessels, reducing blood loss and preventing heavy bleeding.
You should not take this medicine if you are allergic to it, have high blood pressure, have blood poisoning (toxaemia), or are pregnant. Common side effects may include high blood pressure, headache, seizures, stomach pain from uterine contractions, nausea, and vomiting. Your doctor or nurse will give you this medicine at the hospital, so you don’t need to inject it yourself.
This medicine can interact dangerously with some antibiotics, HIV medications, antifungal drugs, and other medicines that affect blood vessels or the heart. It’s essential to inform your doctor about all medications you are taking. If you have liver, kidney, or heart problems, or risk factors like smoking or diabetes, be extra careful when using this medicine. Also, keep it away from newborn medicines to avoid accidental mix-ups.
You should not breastfeed while using this medicine and for at least 12 hours after your last dose. Any breast milk collected during this time should be discarded. The medicine should be stored below 25°C, away from sunlight, children, and pets. Because the medicine is administered by a healthcare professional, missing a dose is unlikely. However, if you suspect a dose was missed, please notify your doctor or nurse immediately.
Product Summary
Offer Price | ₹73.72 |
You Save | ₹23.28 (24% on MRP) |
Contains | |
Uses | Uterine bleeding in the second stage of labour |
Side effects | Abdominal pain, nausea, vomiting |
Therapy | HAEMOSTATICS |
Uses
Contraindications
- If you are allergic to methylergometrine or any other ingredients of Nexbolic injection.
- If you have hypertension.
- If you have toxaemia ( blood poisoning ).
- If you are pregnant.
Side effects
- The most common side effect is hypertension associated in several cases with seizure and/or headache.
- Abdominal pain (caused by uterine contractions)
- Nausea
- Vomiting
Precautions and Warnings
Other General Warnings
- You have liver or kidney problems, be extra cautious with Nexbolic injection, as your body may not handle the drug well.
- You are breastfeeding; do not breastfeed while taking Nexbolic injection. Pumped milk during treatment should be thrown away, and you should wait at least 12 hours after your last dose before breastfeeding again....
- You have heart disease or risk factors like smoking, diabetes, obesity, or high cholesterol, you may have a higher risk of heart problems from Nexbolic injection.
- You store Nexbolic injection at home or in a clinical setting, keep it far away from medications meant for newborns, since giving it to a baby by mistake can be extremely dangerous.
Alcohol
Driving
Pregnancy
Breast Feeding
Directions for Use
Storage and disposal
- Store Nexbolic injection below 25°C, protect it from direct sunlight.
- Do not store above 25°C or freeze.
- Keep it away from children and pets.
- Discard the unused medicine.
Dosage
Overdose
Missed a Dose
Mode of Action
How Does It Work?
Interactions
Interactions with other medicines
- Avoid taking Nexbolic injection with strong antibiotics (such as erythromycin or clarithromycin), HIV medications (like ritonavir or indinavir), or antifungals (like ketoconazole or itraconazole), as these can dangerously increase Nexbolic injection’s effects and lead to serious complications, including narrowed blood vessels or poor blood flow....
- Use caution when taking medications that moderately interact with Nexbolic injection, such as fluconazole, fluoxetine, clotrimazole, and grapefruit juice, as they may still increase the risk of side effects....
- Some drugs, like nevirapine or rifampicin, may reduce how well Nexbolic injection works by speeding up how it is broken down in the body.
- Using beta-blockers with Nexbolic injection may increase the risk of high blood pressure or narrowing of blood vessels.
- Certain anaesthetics can make Nexbolic injection less effective in helping the uterus contract during surgery.
- Nexbolic injection may interfere with heart medications like glyceryl trinitrate, reducing their ability to relieve chest pain.
- Combining Nexbolic injection with other drugs that constrict blood vessels (such as other ergot drugs or prostaglandins) can increase the chance of harmful side effects.
Content Details

Ravindra Ghongade
B. Pharm

Dr. Nikita Toshi
BDS (Bachelor of Dental Surgery), WHO FIDES member
Frequently Asked Questions (FAQs)
Q: How quickly does Nexbolic injection work?
Q: Can Nexbolic injection be used to induce labour?
Q: Is it safe to take Nexbolic injection if I have diabetes?
References
Did you find this medicine information helpful?
Please rate your experience