Migranil Ec Strip Of 10 Tablets
Medical Description
Migranil EC tablet is a combination medicine containing ergotamine and caffeine as active ingredients. It is used to relieve migraine attacks and related headaches. Take this medicine in the exact dose and duration as suggested by your doctor. Do not stop taking this medicine on your own. Do not smoke or consume alcohol when taking this tablet. Migranil EC tablet is not recommended for use in children. Before using this medicine, inform your doctor if you are pregnant, planning a pregnancy, or are breastfeeding and about your detailed medical history.
Product Summary
Offer Price | ₹72.38 |
You Save | ₹9.87 (12% on MRP) |
Contains | Ergotamine(1.0 Mg) + Caffeine(100.0 Mg) |
Uses | Migraine |
Side effects | Muscle pain, weakness, nausea, vomiting |
Therapy | MIGRAINE DRUGS |
Uses of MIGRANIL EC STRIP OF 10 TABLETS
Contraindications of MIGRANIL EC STRIP OF 10 TABLETS
- If you are allergic to ergotamine, caffeine, or any of the other ingredients in Migranil EC tablet.
- If you are suffering from kidney or liver disease.
- If you are suffering from chest pain, coronary heart disease, or high blood pressure.
- If you are suffering from inflammation of the arteries located in the head (temporal arteritis).
- If you are suffering from a blood disorder called porphyria which affects the liver, skin, or blood.
- If you have impaired blood circulation or cramp-like pains in the leg caused by bad circulation.
- If you have an overactive thyroid (hyperthyroidism).
- If you are taking medicines used to treat bacterial infections like quinupristin, dalfopristin, azithromycin, erythromycin, or clarithromycin.
- If you are taking medicines used to treat viral infections like protease inhibitors e.g. amprenavir, ritonavir, nelfinavir, or indinavir.
- If you are taking medicines used to treat fungal infections like ketoconazole or itraconazole.
- If you are taking medicines used to treat ulcers like cimetidine. If you are not sure what these medicines are, please confirm with your doctor.
- If you are pregnant, planning a pregnancy, or are breastfeeding.
Side effects of MIGRANIL EC STRIP OF 10 TABLETS
- Muscle pain
- Nausea
- Vomiting
- Weakness
- Itching
Precautions and Warnings of MIGRANIL EC STRIP OF 10 TABLETS
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
- You are allergic to ergotamine or other ingredients of Migranil EC tablet.
- You are pregnant or breastfeeding.
- You are planning for surgery.
- You have any pre-existing medical condition such as hepatitis, anaemia, heart disease, swollen prostate gland, glaucoma etc.
- You are having problems while urinating.
- You develop cold, tingling, numbness of hands and feet.
- You are addicted to alcohol.
- You are already taking other medications like medicines for hypertension, migraine, brain-related medicines, antifungal medicines, anti-HIV medicines, etc.
- You are elderly..
Directions for Use of MIGRANIL EC STRIP OF 10 TABLETS
- Migranil EC tablet should be taken as directed by your doctor.
- Swallow it as a whole with a glass of water.
- Do not cut, break or chew the medicine.
- Take it at a fixed time for optimal results and do not consume more than the dose prescribed by your doctor.
Storage and disposal of MIGRANIL EC STRIP OF 10 TABLETS
- Store Migranil EC tablets at room temperature in a clean and dry place, protected from moisture, sunlight and heat.
- Keep the medicine out of the reach of children and pets.
Quick Tips of MIGRANIL EC STRIP OF 10 TABLETS
- Migranil EC tablet is used to provide relief in migraine and related headaches. It contains ergotamine and caffeine as main components. In combination it acts by reducing blood flow to the head region, thereby decreasing pain in the head....
- This medicine should not be used for treating any other condition unless specified by the doctor.
- Before starting Migranil EC, inform your doctor if you are pregnant, planning on becoming pregnant, or breastfeeding. Your doctor may recommend you to avoid using this tablet.
- If you notice unusual effects like vomiting, nausea, weakness, or muscle pain, talk to your doctor immediately.
- Inform your doctor if you have hypertension, heart disease, or hepatitis, and about all your other medicines and complete medical history.
- Use of certain medicines like ritonavir, mexiletine, macrolide antibiotics, or quinoline antibacterial along with this medicine must be avoided. Take your doctor's advice before using it.
Dosage of MIGRANIL EC STRIP OF 10 TABLETS
Overdose
Missed a Dose
Mode of Action of MIGRANIL EC STRIP OF 10 TABLETS
How Does It Work?
- Migranil EC tablet is a combination medicine containing ergotamine and caffeine as active ingredients.
- Ergotamine is a vasoconstrictor that works by constriction or narrowing the blood vessels in the head region and reducing the supply of blood to the head. This helps to ease the symptoms of migraine like headaches. ...
- Caffeine also has a similar effect on blood vessels, it also narrows the blood vessels, thereby reducing the blood flow. It is also said to help increase the absorption of ergotamine making it more effective....
Interactions of MIGRANIL EC STRIP OF 10 TABLETS
Interactions with other medicines
- Some medicines can affect the way Migranil EC tablet works or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
- Tell your doctor about all the medicines, supplements, or herbals you are currently taking or might take to avoid any possible interactions.
- Concomitant use of this medicine with liver enzyme (CYP 3A4) inhibitors (ritonavir, nelfinavir, indinavir, amprenavir, azithromycin, erythromycin, clarithromycin) can cause acute ergot toxicity.
- This medicine should be used cautiously along with the medicines used to treat irregular heartbeats (mexiletine).
- Macrolide antibiotics (e.g. clarithromycin, erythromycin) tend to increase the concentration of Migranil EC tablet in the system, thus concomitant use of macrolide antibiotics along with ergotamine containing medicines is contraindicated....
- Quinoline antibacterials such as ciprofloxacin, medicines used to treat fits (phenytoin), medicines used to treat mood disorders (fluvoxamine), medicines used to reduce alcohol addiction (disulfiram), hormonal supplements like oestrogen and progesterone may reduce the elimination of this medicine from the body....
- Other medicines used to treat brain and mood disorders increase the side effects like drowsiness and sleepiness of this medicine.
- Medicines such as atropine when used along with Migranil EC tablet lead to side effects like a dry mouth, blurred vision, constipation, irregular heartbeats, hot and flushed skin, and increased pressure in the eyes....
- Medicines used to treat irregular heartbeats (beta-blockers) when given along with Migranil EC tablet may lead to constriction of the blood vessels.
Interactions with food items
Content Details

Dr. Nikita Toshi
BDS (Bachelor of Dental Surgery), WHO FIDES member

Dr. Ritu Budania
MBBS, MD (Pharmacology)
Frequently Asked Questions (FAQs)
Q: Can Migranil EC tablet cause muscle ache?
Q: I have high blood pressure can I take Migranil EC tablet?
Q: Can Migranil EC tablet be taken by a breastfeeding mother?
Q: What foods do I need to avoid when I am taking Migranil EC tablet?
Q: Can Migranil EC tablets be used regularly to prevent migraine attacks?
Q: What are the contents present in Migranil EC?
Q: What are the side effects of Migranil EC tablets?
Q: Can I take Migranil EC every day?
Q: Why are Migranil EC tablets used?
Q: How to use Migranil EC?
- Migranil EC tablet should be taken as directed by your doctor.
- Swallow it as a whole with a glass of water.
- Do not cut, break or chew the medicine.
- Take it at a fixed time for optimal results and do not consume more than the dose prescribed by your doctor.
References
- Ergotamine and Caffeine: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2022 [cited 30 Apr 2022]
- LactMed - Ergotamine [Internet]. Ncbi.nlm.nih.gov. 2022 [cited 30 Apr 2022]
- CAFERGOT (ergotamine tartrate and caffeine) [Internet]. Accessdata.fda.gov. 2022 [cited 30 Apr 2022]
- Ergotamine [Internet]. Pubchem.ncbi.nlm.nih.gov. 2022 [cited 30 Apr 2022]
- Ergotamine - an overview | ScienceDirect Topics [Internet]. Sciencedirect.com. 2022 [cited 30 Apr 2022]
- CDSCO [Internet]. Cdscoonline.gov.in. 2022 [cited 30 Apr 2022]
- Arnold AC, Ramirez CE, Choi L, Okamoto LE, Gamboa A, Diedrich A, Raj SR, Robertson D, Biaggioni I, Shibao CA. Combination ergotamine and caffeine improves seated blood pressure and presyncopal symptoms in autonomic failure. Front Physiol. 2014 Jul 24 [cited Jan 2025]
- Health Canada. Amoxicillin [Internet]. 2023 [cited 2025 Jan 28]
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