Longacillin 12iu Injection 1ml
By HINDUSTAN ANTIBIOTICS LTD
1ml Injection
MRP ₹12.00
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Longacillin 12iu Injection 1ml Description
Longacillin 12 iu injection is an antibiotic. Treating and managing several different types of bacterial infections like syphilis, rheumatic fever, yaws, etc., is the primary use of the Longacillin 1
2 iu injection. This injection is also used to treat upper respiratory tract diseases. This injection should never be given intravenously or into the vein, as it can cause serious side effects and even death. The main component of this medication is Benzathine penicillin. It belongs to the penicillin group of antibiotics. The mode of action of Longacillin 12 iu injections is to kill the bacteria and lower the infection and symptoms associated with the infection, such as fever, lethargy, etc. This medication is not effective against infections caused by cold, flu, viruses or fungi. Diarrhoea, stomach pain, headache, weakness, nausea, and vomiting are some of the common side effects of Longacillin 12 iu injection. Most of them do not require any medical attention. However, it is best to consult the doctor in case of persisting or worsening symptoms. People allergic to benzathine penicillin should inform their doctor. There are a few contraindications of Longacillin 12 iu injections. For instance, these injections can make birth control pills less effective.
Product Summary
| Offer Price | ₹10.20 |
| You Save | ₹1.80 (15% on MRP) |
| Contains | Benzathine Penicillin |
| Uses | Erysipelas, Primary and secondary syphilis, Latent syphilis (except for neurosyphilis), Yaws (affects the skin, bone and cartilage), Rheumatic fever, Rheumatic carditis (affect the heart, joints, brain, and skin), Poststreptococcal glomerulonephritis |
| Side effects | Headache, Loose stools, Stomach discomfort, Joint pain, Vomiting, Skin rash |
| Therapy | ANTIBIOTIC |
Check more medicines with composition as Benzathine Penicillin
Uses of Longacillin 12iu Injection 1ml
- As per CDSCO and USFDA, Longacillin 12 iu injection is indicated
- For the treatment of:
- Erysipelas, a skin infection
- Primary and secondary syphilis
- Latent syphilis (except for neurosyphilis)
- Yaws (affects the skin, bone and cartilage)
- For the prophylaxis (prevention) of:
- Rheumatic fever; to manage chorea (involuntary movements), rheumatic carditis (affect the heart, joints, brain, and skin)
- Poststreptococcal glomerulonephritis, a rare kidney disorder that can develop after group A strep infections
Contraindications of Longacillin 12iu Injection 1ml
- If you have a history of serious hypersensitivity to Benzatheine penicillin or other similar antibiotics (e.g., penicillins or cephalosporins). Allergies to this medicine are common. So, hypersensitivity should be checked before giving this injection....
- If you want to give this medicine intravenously or into the vein.
- If you are using local numbing medicine, such as lidocaine, with this injection.
- If you are using Longacillin injection in areas with low blood flow.
- If you have a history of breathing disorders such as severe asthma. It increases the risk of an allergic reaction.
- If you have severe kidney impairment; the dose should be checked, or it should not be given.
- If you are at risk of encephalopathy.
- If you are diagnosed with bacteria-associated diarrhoea. It has been reported with the use of nearly all antibiotics, including Longacillin 12 iu injection and may range in severity from mild diarrhoea to fatal colitis. Treatment with antibiotics alters the colon's normal flora, leading to the overgrowth of bacteria....
- If you are not correctly diagnosed with a suspected bacterial infection. Using this medicine in such cases does not benefit the patient and increases the risk of developing treatment-resistant bacteria....
Side effects of Longacillin 12iu Injection 1ml
- Headache
- Loose stools
- Stomach discomfort
- Joint pain
- Nausea and vomiting
- Skin rash
Precautions and Warnings of Longacillin 12iu Injection 1ml
Pregnancy
Q:
Can I take the Longacillin 12 iu injection during pregnancy?
A:
There is no evidence of harm to the foetus due to Longacillin 12 iu injections. There are, however, no adequate information and well-controlled studies of Longacillin 12 iu injections in pregnant women. These injections should be used during pregnancy only if needed. Please consult your doctor before using them.
Breast Feeding
Q:
Can I take the Longacillin 12 iu injection while breastfeeding?
A:
Longacillin 12 iu injections are excreted in human milk. This medicine used by breastfeeding mothers may lead to the sensitisation of infants. Caution should be exercised when Longacillin 12 iu injections are given to a nursing woman. Please consult your doctor before using them.
Driving
Q:
Can I drive if I have taken the Longacillin 12 iu injection?
A:
These injections can cause side effects such as allergic reactions, dizziness and convulsions. These can make you unfit to drive. Do not drive or operate machinery if you are feeling unwell.
Alcohol
Q:
Can I consume alcohol with the Longacillin 12 iu injection?
A:
No, the safety of alcohol with Longacillin 12 iu injections is not established. It is better not to have alcohol with this injection.
Other General Warnings
Talk to your doctor if
- You have a kidney or liver illness.
- You have watery or bloody diarrhoea.
- You have a skin rash, itching, redness, and other allergic reactions.
- You have liver-related issues like jaundice (yellowing of skin and eyes), raised liver function test, etc.
- You have a history of kidney stones.
- You have a common cold or flu.
- You are using this injection for a long time or more than once a week.
- You notice any central nervous system effects like dizziness, confusion, altered levels of consciousness, epilepsy or movement abnormalities, etc.
Mode of Action of Longacillin 12iu Injection 1ml
How Does It Work?
Longacillin 12 iu injection contains Benzathine penicillin. It is similar to penicillin in its antibacterial action against susceptible bacteria. It works during the stage of active multiplication of the bacteria. It acts by stopping the cell wall synthesis during the growth phase, which causes the death of the bacteria.
Some bacteria develop resistance to this medicine. The resistance mechanism works primarily through modifying the structure of proteins produced by the bacteria. When that happens, this medicine is not effective....
Directions for Use of Longacillin 12iu Injection 1ml
- Longacillin injection is given to the patient in the hospital by the treating doctor or a nurse.
- Do not take this injection by yourself.
- Do not stop using this injection in the middle of the treatment.
- This injection is given only into a muscle (IM) and never intravenously (IV)
- It is injected into the buttocks or thigh.
- A gap of a few days should be maintained between two doses or as your doctor prescribes.
- Follow the instructions given by the doctor during the injection and for aftercare.
- If you are having any breathing problems, rash, or swelling, inform your doctor immediately.
- Try to take Longacillin 12 iu injection with food to prevent any stomach pain or discomfort.
Interactions of Longacillin 12iu Injection 1ml
Interactions with other medicines
- It is not recommended to take Probenecid medication along with Longacillin 12 iu injections. Probenecid decreases the elimination of benzathine penicillin by the kidneys. It may result in increased and prolonged blood levels of amoxicillin....
- Using Longacillin 12 iu injections while you are on oral anticoagulants or blood thinners like warfarin is not advised. They may cause prolongation of prothrombin time (test measures how long it takes for a clot to form in a blood sample). It increases the risk of bleeding. Dose adjustment is necessary....
- Using methotrexate and Longacillin 12 iu injections at the same time can reduce the excretion of methotrexate, which can increase its toxicity.
- Intamax O injections lower the potency of oral contraceptive pills (combined estrogen and progesterone contraceptive pills). It is advised to use other modes of contraception.
- Using other types of antibiotics such as Chloramphenicol, macrolides, sulfonamides, and tetracyclines may interfere with the antibacterial effects of Longacillin 12 iu injections.
Interactions with food items
- There is no information available on the interaction of food with Longacillin 12 iu injection.
Storage and disposal of Longacillin 12iu Injection 1ml
Store Longacillin injection below 30 degrees celsius. Do not let the medicine freeze. Store it in the original container to keep them away from direct sunlight. Keep longacillin injection away from pets and children.
Dispose of the packaging carefully after use. Do not use the medicine if the package has been opened. Check the expiration date on the packaging before taking the injection. If the medicine is past the expiration date, do not use it. Dispose of unused/expired medicine as biomedical waste....
Dosage of Longacillin 12iu Injection 1ml
Overdose
In a small number of patients, an overdose of Longacillin 12 iu injections can cause symptoms such as twitching and seizures, headache, fast heartbeats, shortness of breath, feeling tired or light-headed, or skin that is pale, gray, or blue. It may also cause a serious condition called methemoglobinemia (red blood cells cannot carry oxygen). In case of an overdose of Longacillin injection, consult your doctor and seek treatment as soon as possible....
Missed a Dose
Longacillin injection is given at a hospital by the doctor or a nurse. If you forget to go to the hospital, take it as soon as you recall. Consult your doctor if you have any confusion regarding this. Do not take both doses at the same time to make up for the missed dose....
Content Details
WRITTEN BY
REVIEWED BY
Dr. Vijay Y
MBBS, MD in Clinical Pharmacology
Frequently Asked Questions (FAQs)
Q: Can we use Longacillin 12 iu injections in children?
A: This injection is given to children and neonates of all ages to treat very serious types of infection. The dosing of Longacillin 12 iu injections should be modified according to the child's age.
Q: Can persons older than 65 years use Longacillin 12 iu injections?
A: Older adults over 65 respond differently from younger people. Please consult your doctor for the appropriate dose of Longacillin 12 iu medicine.
Q: Can I take Longacillin 12 iu injection if I have a kidney condition?
A: This medicine is well tolerated in kidney failure, but the risk of toxic reactions to Longacillin 12 iu injection may be greater in persons with impaired kidney function. Consult your doctor in such cases. The dose should be carefully monitored.
References
View All
- Bicillin® L-A (penicillin G benzathine injectable suspension)[internet]. accessdata.fda.gov. [cited 31 Mar 2022] - Available from:
- Penicillin G Benzathine injection: Medlineplus Drug Information [Internet]. MedlinePlus. U.S. National Library of Medicine; [cited 31 Mar 2022]. Available from:
- Benzylpenicillin benzathine 2.4 million I.U. Powder and solvent for suspension for Injection [Internet]. Benzylpenicillin benzathine 2.4 Million I.U. powder and solvent for suspension for injection - Summary of Product Characteristics (SmPC) - (emc). [cited 31 Mar 2022]. Available from:
- CDSCO [Internet]. Cdscoonline.gov.in. 2022 [cited 31 Mar 2022]. Available from:
- Procaine penicillin G [Internet]. Drugs and Lactation Database (LactMed) [Internet]. U.S. National Library of Medicine; 2021 [cited 31 Mar 2022]. Available from:
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