Jardiance Met Tablet

• Jardiance MetTablet is used to manage type 2 diabetes mellitus along with diet and exercise:
• in adults whose diabetes is not adequately controlled by metformin alone or metformin with other medicines for diabetes.
• in patients already being treated with a combination of empagliflozin and metformin as separate medicines.

• If you are allergic to empagliflozin, metformin or any of the other ingredients of Jardiance MetTablet.
• If you have any type of metabolic acidosis (a condition where there is too much acid in the body fluids) like lactic acidosis or diabetic ketoacidosis.
• If you had a diabetic pre-coma.
• If you have kidney failure or liver problems.
• If you have any condition which may affect your kidneys like severe infection, dehydration (due to severe vomiting/diarrhoea or less fluid intake) or shock.
• If you have any disease which may cause a deficiency of oxygen supply to the tissues, like heart failure, respiratory failure, recent heart attack or shock.
• If you drink large amounts of alcohol.

• Nausea
• Vomiting
• Abdominal pain
• Diarrhoea
• Loss of appetite

Other General Warnings

• You have a kidney or liver disorder.
• You have uncontrolled diabetes or a serious infection.
• You have been fasting for a long duration or you consume alcohol.
• You are dehydrated (due to severe vomiting/diarrhoea, fever, excessive heat or reduced fluid intake).
• You have a disease in which a part of the body has a reduced supply of oxygen.
• You develop any symptoms of lactic acidosis like vomiting, stomach pain, muscle cramps, a general feeling of not being well, tiredness, difficulty in breathing and reduced body temperature.
• You experience symptoms like rapid weight loss, nausea, vomiting, stomach pain, excessive thirst, fast and deep breathing, confusion, unusual sleepiness or tiredness, a sweet smell to your breath, a sweet or metallic taste in your mouth or a different odour to your urine or sweat after taking this medicine.
• You have type 1 diabetes – a condition where your body does not produce any insulin.
• You are not able to eat or drink.
• You are taking medicines called diuretics that increase the production of urine or lower blood pressure.
• You are elderly (over 75 years old).
• You have a serious infection of the kidney or the urinary tract with fever.
• You need to undergo an examination with iodination contrast agents (such as an X-ray or scan).
• You develop symptoms like pain, tenderness, redness, swelling of the genitals or the area between the genitals and the anus with fever or feeling generally unwell.

• Take Jardiance MetTablet as a whole with sufficient water.
• Always take this medicine exactly as prescribed by your doctor.
• Take this medicine at the same time every day, preferably with meals for optimal benefits.
• Do not cut, break or chew the medicine.
• Do not consume more than the prescribed dose.
• Do not discontinue the medicine on your own without consulting your doctor.

• Store Jardiance MetTablet in a cool and dry place away from direct sunlight.
• Keep it out of reach of children and pets.

Overdose

• If you think you have taken too much of Jardiance MetTablet, contact your doctor immediately or visit the nearest hospital.

Missed a Dose

• You should never miss your blood sugar medicines as they may lead to fluctuations in your blood sugar level.
• However, if you missed any dose of Jardiance MetTablet, take it as soon as you remember.
• If it's time for your next dose, then skip the missed dose and continue with your regular dosing schedule.
• Do not take a double dose to compensate for the missed one.

How Does It Work?

Interactions with other medicines

• Some medicines can affect the way Jardiance MetTablet works or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
• Inform your doctor about all the medicines, supplements or herbals you are currently taking or might take to avoid any possible interaction.
• Particular care should be taken if you are taking medicines for treating fluid accumulation (diuretics), medicines that lower blood sugar levels (insulin, sulphonylurea), irregular/abnormal heartbeat (verapamil), tuberculosis (rifampicin), ulcers/stomach acidity (cimetidine), HIV (dolutegravir), heart-related chest pain (ranolazine), bacterial infections (trimethoprim), cancer (vandetanib, crizotinib, olaparib), fungal infections (isavuconazole), asthma (beta-2 agonists like salbutamol), inflammation (corticosteroids like prednisone), pain and inflammation (NSAID and COX-2-inhibitors like ibuprofen and celecoxib), high blood pressure (ACE inhibitors like enalapril and angiotensin II receptor antagonists like losartan), medicines that contain alcohol, iodinated contrast agents (medicines used during an X-ray or scan).
• Jardiance MetTablet may lower the levels of lithium (used to treat mental disorders) in the blood.