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Glyfix 1mg Tab

10 Tablet(s) in Strip
15% OFF
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Therapeutic classification:


Medical Description

Glyfix 1mg Tab contains Glimepiride, which is a diabetes medicine.

Uses of Glyfix 1mg Tab

  • It is used for Type 2 diabetes mellitus when diet and exercise have not been able to control your blood glucose levels.

Contraindications of Glyfix 1mg Tab

  • If you have an allergy to Glimepiride or Sulfonylureas or Sulfonamides or any other ingredients of this medicine
  • If you have Type1 diabetes
  • If you have some of the following signs like fatigue, nausea, frequent urination and muscle stiffness (due to diabetic ketoacidosis)
  • If you have severe kidney or liver disease

Side effects of Glyfix 1mg Tab

  • Abnormal taste sensation
  • Weight gain
  • Lightheadedness or dizziness
  • Severe low blood sugar level (hypoglycaemia) including loss of consciousness, fits or coma
  • Allergic reactions like skin rash, breathing difficulty, drop in blood pressure
  • Abnormal liver function including yellowing of the skin and eyes (jaundice), itchy skin, dark colored urine, pale stool or tar-colored stool

Precautions and Warnings of Glyfix 1mg Tab


Can I take Glyfix 1mg Tab during pregnancy?
This medicine should not be used during pregnancy. Inform your doctor if you are pregnant, think you may be pregnant or planning to have a baby, your doctor may switch to insulin therapy.

Breast Feeding

Can I take Glyfix 1mg Tab while breastfeeding?
  • Glimepiride may pass into breast milk and should not be taken during breastfeeding
  • If you are on Glimepiride medication (prescribed by a physician), then monitor your breastfed baby for signs of low blood glucose levels such as irritation, sleepiness, poor feeding, fits, low body temperature
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Can I drive if I have consumed Glyfix 1mg Tab?
  • Glyfix 1mg Tab can cause low blood sugar levels which can lead to drowsiness, unconsciousness, confusion. These can be dangerous while driving
  • Consult your doctor whether you can drive a car if you have frequent episodes of hypoglycaemia
  • Keep a juice or a bar of chocolate in the car close to you while driving, in case you start feeling any of the above symptoms of hypoglycaemia, immediately drink the juice or eat the chocolate bar
  • Note that artificial sweeteners are not of any use in such scenarios


Can I consume alcohol with Glyfix 1mg Tab?
Be cautious not to drink alcohol on an empty stomach. Alcohol increases the risk of low blood sugar.

Other General Warnings

Talk to your doctor if
  • You experience extreme hunger, headache, nausea, vomiting, sleepiness, restlessness, aggression, reduced alertness and reaction time, confusion, shakiness, dizziness. These could be signs of low blood sugar. If you have any of these, immediately have sugar or sweet juice
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  • You are suffering from severe liver disease or kidney disease
  • You have G6PD deficiency, and Glimepiride can cause hemolytic anaemia (destruction of red blood cells)

Mode of Action of Glyfix 1mg Tab

How Does It Work?

  • Your pancreas produces a hormone called insulin
  • Insulin moves sugar (glucose) from the blood into the cells
  • The cells then use it as fuel for energy
  • In Type 2 diabetes, your body doesn’t make enough insulin or doesn’t utilize insulin properly, so the sugar is not able to enter the cells and stays in your bloodstream
  • Glimepiride increases the amount of insulin released from your pancreas. This insulin then lowers your blood sugar levels

Directions for Use of Glyfix 1mg Tab

  • Take this medicine with or after a meal to reduce its side effects
  • Take the tablet as a whole with a glass of water

Interactions of Glyfix 1mg Tab

Interactions with other medicines

  • These medicines along with Glimepiride can cause drastic fall in blood glucose levels: Fluconazole, Aspirin, antidiabetic products like Metformin, Insulin, Warfarin, Ramipril, Lisinopril, Allopurinol
  • These medicines can interfere with Glimepiride and cause increase in blood glucose: Oestrogens, Progestogens, Diuretics, Levothyroxine, Rifampicin, Glucocorticoids, Chlorpromazine
  • Beta-blockers (e.g., Propranolol) pose the risk of excessive fall in blood sugar levels. They may also hide sure signs of low blood sugar

Interactions with food items

You should have a diabetic diet as advised by your doctor or dietician. This medicine works best along with a proper diet and exercise. Exercise is known to decrease insulin resistance.

Storage and disposal of Glyfix 1mg Tab

This medicine does not require any special storage conditions. Try to keep it out of the reach of children.

Dosage of Glyfix 1mg Tab


  • Overdose can cause low blood sugar levels which can cause nausea, vomiting, restlessness, tremor, visual disturbances, sleepiness, coma
  • Immediately consume some sugar or sugar-containing drink
  • If the person has fainted, do not give food or drink
  • You must seek immediate emergency medical care if you suspect an overdose

Missed a Dose

  • If you missed any dose take it as soon as you remember
  • If it is time for the next dose, skip the missed dose and continue your regular dosing schedule
  • Do not take a double dose of medicine to compensate for a missed one
  • Taking a dual dose can lead to a dangerous fall in blood glucose level

Frequently Asked Questions (FAQs)


Q: Which blood tests should I do to check if my diabetes is under control?

  • You may do tests like fasting blood glucose, post-meal blood glucose (postprandial blood glucose), HbA1C
  • It is advisable to do tests like kidney/ renal function test, liver function test, an eye test, at least once a year as diabetes is known to affect your eyes, liver and even kidneys

Q: What diet should I follow along with the medicinal treatment?

  • Diet should include chapatis, multigrain bread, rice with vegetables, sprouts, roasted grams, plain cooked dal, soups, steamed vegetables, vegetables cooked with less oil, jamun berry, orange, guava, apple, watermelon, papaya, cow’s milk, curd, thin buttermilk, fish (grilled, baked or steamed), peanuts, cashew nuts, walnuts (handful)
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  • Drink at least 8-10 glasses of water daily
  • A diet should be high in fibre, low in fat with adequate protein, carbohydrates, vitamins and minerals
  • Avoid maida, white bread, potato, noodles, corn flakes, poori, biryani, naan, fried rice, etc.
  • Avoid cream soups, carrot juice, deep-fried vegetables, packaged food

Q: My blood sugar drops quite often. What should I do?

  • Talk to your doctor about these frequent episodes of low blood glucose, if need be your doctor may decrease the dose of your medicine or change its timing
  • Have your meals at fixed schedules, never skip or delay your meals
  • Do not drastically change your diet unless told by your doctor or dietician
  • Avoid excessive intake of alcohol
  • Do not over excercise
Last Updated on: 31 Jul 2020 | 07:00 PM (IST)

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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts. Please click here for detailed T&C.
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  • Uses
  • Contraindications
  • Side effects
  • Precautions and Warnings
  • Mode of Action
  • Directions for Use
  • Interactions
  • Storage and disposal
  • Dosage
  • FAQs
  • References
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