Extensior 0.25Mg Pre Filled Pen Of 1.5Ml Solution For Injection

• As an adjunct to diet and exercise to improve glycaemic control in adults with type 2 diabetes mellitus
• Risk reduction in adults with type 2 diabetes mellitus and heart disease
• Risk reduction in adults with type 2 diabetes mellitus and chronic kidney disease

• As an adjunct to diet and exercise to improve glycaemic control in adults with type 2 diabetes mellitus

• Risk reduction in adults with type 2 diabetes mellitus and heart disease

• Risk reduction in adults with type 2 diabetes mellitus and chronic kidney disease

• Extensior solution for injection is contraindicated in patients with:
• A personal or family history of medullary thyroid carcinoma (MTC) or in patients with Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).
• A known allergy to semaglutide or any of the excipients in Extensior solution for injection.

• Nausea
• Diarrhea
• Vomiting
• Constipation
• Abdominal pain
• Decreased appetite
• Fatigue

Other General Warnings

• You have a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).
• You experience symptoms of thyroid tumors (e.g., a mass in the neck, difficulty swallowing, difficulty breathing, persistent hoarseness).
• You experience persistent severe abdominal pain, sometimes radiating to the back, and which may or may not be accompanied by vomiting (symptoms of acute pancreatitis).
• You experience symptoms of gallbladder disease, such as cholelithiasis or cholecystitis.
• You have diabetes and experience signs or symptoms of hypoglycemia (low blood sugar), especially if you are taking insulin or a sulfonylurea.
• You experience severe gastrointestinal reactions (nausea, vomiting, or diarrhea) that could lead to dehydration.
• You have kidney impairment and experience any adverse reactions that could lead to volume depletion.
• You experience signs or symptoms of a serious allergic reaction (e.g., anaphylaxis, angioedema).
• You have a history of diabetic retinopathy.
• You experience palpitations or a racing heartbeat at rest.
• You experience the emergence or worsening of depression, suicidal thoughts or behavior, and/or any unusual changes in mood or behavior.
• You have a history of suicidal attempts or active suicidal ideation.
• You planning any elective surgeries or procedures requiring general anaesthesia or deep sedation?

• Use the medicine exactly as prescribed by your doctor. It is administered as a subcutaneous
• injection on the abdomen, thigh, or upper arm, usually once a week. Use a new needle for each
• injection and do not change the dose unless advised by your doctor.

• Store the Extensior solution for injection in the refrigerator between 2°C to 8°C.
• Do not freeze Extensior solution for injection.
• Keep Extensior in the original carton to protect it from light.

• Administer Extensior 0.25mg Injection on the same day each week. Set a reminder to help you stay on track.
• To prevent skin irritation or lumps, administer the medication to different areas of the abdomen, thigh, or upper arm.
• Check your blood sugar levels regularly to prevent hypoglycemia (low blood sugar) if you are taking concurrent medications such as insulin or sulfonylureas, and address any unexpected symptoms.
• Eat small, frequent, balanced meals, and avoid greasy, high-fat foods to reduce nausea.
• Drink plenty of water to counteract dehydration caused by nausea, vomiting, or diarrhea.
• Be watchful for symptoms such as severe stomach pain, signs of pancreatitis (such as severe upper abdominal pain that may radiate to the back, along with nausea, vomiting, or fever), or allergic reactions, and consult a doctor immediately if they occur.
• Let doctors know you are using Extensior 0.25mg Injection before surgeries, as it may delay stomach emptying.

Overdose

Missed a Dose

• Extensior 0.25mg Injection (injectable rDNA semaglutide) mimics a naturally occurring hormone called GLP-1 (Glucagon-Like Peptide-1), which plays a key role in regulating blood sugar levels.
• It stimulates insulin release when needed, reduces excess liver sugar production, and slows stomach emptying, thereby improving blood sugar control. By supporting these processes, Extensior 0.25mg Injection helps improve overall blood sugar management. It also helps reduce the risk of certain heart and kidney complications associated with type 2 diabetes.

Interactions with other medicines

• Extensior solution for injection can slow stomach emptying, which may affect the absorption of certain oral medications.
• The risk of hypoglycemia is increased when Extensior solution for injection is used with insulin or insulin secretagogues (e.g., sulfonylureas). A lower dose of insulin or the insulin secretagogue may be needed.
• It is not recommended to use Extensior solution for injection with other semaglutide-containing products or other GLP-1 receptor agonists.

Interactions with food items