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Estadep Plus Strip Of 10 Tablets

10 Tablet(s) in Strip
We do not sell this product

Made by

GNOSIS PHARMACEUTICAL PVT LTD

Dosage

TABLET

Expiry

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Product Summary

Uses
Treatment of anxiety disorder and comorbid depression
Therapy
Anti-anxiety and anti-depressant
Side effects
Nausea, Fatigue, Confusion, Drowsiness, Increased sweating, Insomnia, Sexual dysfunction
3 Step Quality
Assurance
Cash on delivery
available
NPPA
Regulated

Medical Description

Estadep Plus tablet is used to treat comorbid depression and anxiety disorders. It contains clonazepam and escitalopram as active ingredients. Estadep Plus Tablet helps relax mood by lowering the excess activity of nerves in the brain. It also has sedative effects that relieve anxiety and improve sleep. Depression is a mood disorder characterised by episodes of sadness, loss of interest, mood swings, hopelessness, etc. In contrast, anxiety is characterised by episodes of excessive, unrealistic worry and fear that can interfere with daily activities. Estadep Plus tablet should only be taken after a doctor’s consultation. The dose of the Estadep Plus tablet should be carefully monitored, as there are many side effects associated with this medicine, especially in older patients and persons with liver and kidney disorders.

Uses

  • As per CDSCO, the Estadep Plus tablet is used for the following cases:
  • Treatment of comorbid depression (depression associated with other disorders)
  • Treatment of anxiety disorder

Contraindications

  • Estadep Plus Tablet is contraindicated in the following cases:
  • If you are allergic to any active component of Estadep Plus tablet, i.e. Clonazepam, Escitalopram
  • If you are already taking Monoamine Oxidase Inhibitors (MAOIs): linezolid, methylene blue, Selegiline, antipsychotic medicine-pimozide, anti-anxiety or sedative medications
  • If you are diagnosed with acute angle glaucoma (an eye condition that increases the fluid pressure in the eyes)
  • If you have a seizure disorder and taking antiepileptic (anti-seizure) medications
  • If you have liver or kidney disease
  • If you have respiratory issues
  • If you have a severe heart condition
  • If you are pregnant or breastfeeding

Side effects

  • The side effects of the Estadep Plus tablet includes the following:
  • Nausea
  • Fatigue
  • Confusion
  • Drowsiness
  • Increased sweating
  • Insomnia
  • Sexual dysfunction

Precautions and Warnings

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Pregnancy

No, the Estadep Plus tablet is not recommended during pregnancy. Clinical research data have shown harmful effects of the medicines on the developing baby inside the womb. Pregnant women are advised to take this medicine only if it is recommended by their doctor or in some life-threatening condition. The doctor will weigh the benefits versus risks before prescribing these medications.

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Breast Feeding

The Estadep Plus tablet is not recommended during breastfeeding as it may pass into breast milk and can affect the baby. Consult your doctor and discuss the potential risks and benefits of taking this tablet.

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Driving

Consumption of Estadep Plus tablets may cause side effects that could hamper your driving ability. These medications may decrease your alertness and affect your vision, and cause dizziness while driving. Therefore, it is better to avoid driving if you are experiencing these side effects.

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Alcohol

No, do not consume alcohol with Estadep Plus Tablet as it exaggerates the severity of side effects like drowsiness, confusion, sedation, blurred vision, lethargy, etc. It may also interfere with medicine efficacy.

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Other General Warnings

Talk to your doctor if
  • You have any allergic reactions after taking the Estadep Plus tablet.
  • You experience sudden mood or behaviour changes.
  • You have any suicidal ideation or self-harming thoughts.
  • You notice a sudden loss of vision.
  • You feel there is worsening of the symptoms.
  • You have trouble breathing or talking.
  • You have mild or severe liver or kidney disease; this medicine may need a dose adjustment.
  • You are taking medication for other conditions or any health supplements.

Directions for Use

  • Take the Estadep Plus tablet as per the doctor’s prescription.
  • Take the medicine with or without food or as prescribed. In the case of any stomach illness, take it after meals.
  • Take Estadep Plus tablet preferably at the same time every day to maintain its constant level in the body.
  • Do not break/crush the tablet or chew this medicine; take it as a whole with a glass of water.
  • Do not take Estadep Plus tablet with other medications; consult your doctor first.
  • Do not stop taking this medication in between, as it may lead to withdrawal side effects.
  • Do not exceed the dosage on your own without consulting a doctor.

Storage and disposal

Store Estadep Plus tablet away from sunlight. Keep it at room temperature in a cool and dry area. Keep it away from children and pets. Keep the medicine within its original packaging. Do not flush Estadep Plus tablets down into the toilet or throw them into the dustbin unless instructed to do so. Medicines disposed of in this manner may contaminate the environment. Properly dispose of this product when it is expired or no longer required.

Dosage

Overdose

Estadep Plus tablet overdose can lead to side effects like irregular heartbeat, low blood pressure, slowing of heart rate, sleepiness, double vision, difficulty breathing, cardiac arrest, ECG changes (change in heart functioning) and coma. If you experience any of these symptoms or have taken an overdose of this medicine, immediately seek emergency medical treatment from a nearby hospital.

Missed a Dose

If you missed a dose of your Estadep Plus tablet, take it as soon as you remember. If you recall missing a dose when it is almost the time to take the next dose, skip the missed one and continue with your regular dosing schedule. Do not use them together, as this can lead to an overdose.

Mode of Action

How Does It Work?

Estadep Plus Tablet contains two active ingredients: Clonazepam and Escitalopram. Clonazepam is a benzodiazepine that acts as a GABA-A (Gamma Amino Butyric Acid) receptor agonist. GABA is an inhibitory neurotransmitter. By binding to the GABA-A receptor, it enhances the inhibitory effects of GABA, resulting in sedative, anti-anxiety and muscle relaxant properties and thus, relieving anxiety and depression symptoms. Escitalopram is an antidepressant belonging to the Selective Serotonin Reuptake Inhibitors (SSRIs) class of medicine. It works by preventing the reuptake of a chemical messenger called serotonin by the nerve cells, resulting in an increased serotonin level in the brain. Serotonin is a natural chemical messenger responsible for controlling behavioural processes such as mood, fear, anger, appetite, memory, etc.

Interactions

Interactions with other medicines

  • Many medicines can interact with the Estadep Plus tablet, making it less effective or increasing side effects.
  • Estadep Plus tablet should not be used concomitantly or within two weeks of using Monoamine Oxidase Inhibitors (MAOIs) like isocarboxazid, linezolid, methylene blue, selegiline, rasagiline, etc. It is potentially life-threatening.
  • Concomitant use of Estadep Plus tablet with antidepressants like Clomipramine, Desipramine, Imipramine, Amitriptyline, Amoxapine, etc.; opioids and other central nervous system depressants is contraindicated, as it may cause respiratory depression, coma and death.
  • Estadep Plus tablet interaction with metoprolol can lead to excessive bradycardia (slow heart rate).
  • Estadep Plus tablet interaction with antipsychotics (pimozide, haloperidol), tricyclic antidepressants and antihistamines can prolong QT interval on ECG and may alter heart rhythm.
  • Estadep Plus tablet interaction with NSAIDs, aspirin, and other medications that affect coagulation can increase the risk of bleeding and bruises.
  • Estadep Plus tablet may also interact with herbal medicine like St John’s wort and lead to life-threatening side effects.

Interactions with food items

  • Avoid consuming Estadep Plus tablets with cola drinks, chocolates, and caffeine-containing drinks like tea and coffee. It can result in serotonin syndrome (characterised by high blood pressure, confusion, and muscle rigidity). It would help if you also avoided tyramine-rich beverages like cheese, milk, beef, chicken liver, meat extract, soybeans and grapefruit.

Frequently Asked Questions (FAQs)

Generally, the Estadep Plus tablet is not recommended for children below ten years of age as the safety and efficacy of this medicine is not clinically established for this age. Also, this medicine should be used with caution in elderly patients because they may have other illnesses

Yes, abruptly stopping the consumption of Estadep Plus tablet causes withdrawal symptoms such as agitation, nausea, tremor, confusion, diarrhoea, vomiting and sweating. Consult your doctor before stopping the consumption of the medicine, as doses need to be tapered slowly to avoid undesirable side effects.

Estadep Plus tablet can cause decreased sexual drive, problems getting an erection and ejaculating, difficulty achieving orgasm in women. These side effects usually tend to resolve on their own after a couple of weeks. However, if you experience these side effects for a longer duration, consult your doctor.

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Manufacturer Details

Manufacturer Name:GNOSIS PHARMACEUTICAL PVT LTD

Address:<p>1. Via Lavoratori Autobianchi, 1, 20832 Desio (MB) - Italy</p>

Country of Origin:India

Vendor Details

Fulfillment Information: Estadep Plus Tablet (10) will be delivered by a licensed retail pharmacy nearest to your location. Order acceptance and fulfillment are dependent upon the verification of your doctor's valid prescription (where applicable) and the current stock of this medicine.

References:

In Case of Any Issues Contact Us

Email Id:care@pharmeasy.in

Phone Number:7666100300

Address:D-37/1, Opp. Sandoz, TTC Industrial Area, MIDC Industrial Area, Turbhe, Navi Mumbai, Maharashtra 400703

Disclaimer

The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here  for detailed T&C.

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