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Ematra 10Mg Bottle Of 100 Capsules

100 Capsule(s) in Bottle

MRP ₹9631.00

₹7704.80

20% OFF

₹77.05/capsule (Inclusive of all taxes)
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  • Ematra 10Mg Bottle Of 100 Capsules

Made by

EMCURE PHARMACEUTICALS LTD

Dosage

CAPSULE

Expiry

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Product Summary

Uses
Acute promyelocytic leukemia
Therapy
Anti-acne
Side effects
Headache, fever, dry skin, dry mouth or lips, skin redness, bone pain, tiredness, nausea, vomiting, and temporary digestive upset.
Salt Content
Tretinoin(10.0 Mg)
3 Step Quality
Assurance
Cash on delivery
available
NPPA
Regulated

Medical Description

Ematra capsule contains tretinoin, a natural retinoic acid compound used as a differentiating agent in cancer therapy. It acts in the body to help immature, cancerous blood cells mature into more mature, functional white blood cells.

It attaches to target sites inside cells to restore normal gene regulation and differentiation, helping immature leukemic cells mature normally and eventually die. This helps reduce cancerous cells and restore normal blood cell production without using cytotoxic chemotherapy mechanisms.

Common side effects of Ematra capsule include headache, fever, dry skin, dry mouth or lips, skin redness, bone pain, tiredness, nausea, vomiting, and temporary digestive upset.

Contact your doctor immediately if you experience signs of an allergic reaction (such as a skin rash, itching, or swelling of the face, lips, or throat), sudden shortness of breath, severe chest pain, persistent high fever, rapid weight gain, swelling in your legs, or severe headache with visual disturbances.

Ematra capsule is taken orally as capsules, as specifically prescribed by your doctor.

Uses

Used for the induction of remission in acute promyelocytic leukemia (APL), a blood cancer.

Contraindications

Ematra capsule should not be used:
  • If you have a known severe hypersensitivity or systemic allergic reaction to tretinoin, retinoids, or any of its ingredients (including soybean oil or gelatin).
  • During pregnancy. Tretinoin is highly teratogenic and must not be used during pregnancy.

Side effects

Common Side Effects
  • Headache and tiredness
  • Dry skin, dry lips (cheilitis), and dry nose or mouth
  • Nausea, vomiting, and stomach discomfort
  • Bone, joint, or muscle pain
  • Dizziness and lightheadedness
  • Skin rash, itching, or redness
  • Temporary hair thinning
  • Mild fever or chills
Serious Side Effects (Seek Immediate Medical Care)
  • APL Differentiation Syndrome: Sudden high fever, severe shortness of breath, chest pain, lung fluid buildup, rapid weight gain, or swelling of legs and feet.
  • Increased pressure in the brain: Severe, persistent headache with nausea, vomiting, or blurred/double vision.
  • Severe Allergic Reaction (Anaphylaxis): Severe rash, skin blistering, swelling of the face, low blood pressure, or sudden trouble breathing.
  • Severe liver or blood-fat problems: Tretinoin may significantly increase liver enzymes or blood fats, especially triglycerides, so regular blood tests are needed.

Precautions and Warnings

Pregnancy

Pregnancy

No. Ematra capsule must not be used during pregnancy, as tretinoin can cause severe birth defects. Women who can become pregnant should use effective contraception before and during treatment and for the period advised by their oncologist. Pregnancy testing is required as directed by the treatment protocol.

Breast Feeding

Breast Feeding

Breastfeeding is not recommended during treatment with Ematra capsule. It is not known whether tretinoin passes into human milk, but because of potential serious adverse reactions in nursing infants, discuss alternative feeding options with your oncologist.

Driving

Driving

Avoid driving or operating machinery if you experience severe headaches, fatigue, dizziness, or visual changes during your treatment.

Alcohol

Alcohol

There is no specific established alcohol interaction with tretinoin. However, alcohol may worsen symptoms such as dizziness, nausea, or headache. Discuss alcohol consumption with your oncologist.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • Have previously had a serious allergic reaction to tretinoin or retinoid formulations.
  • Develop sudden breathing difficulty, high fever, chest discomfort, or swelling in your limbs.
  • Experience severe, continuous headaches accompanied by nausea, vomiting, or vision changes.
  • Have a history of liver disease, high lipid levels, or kidney impairment.
  • Develop severe or persistent headache, nausea, vomiting, visual changes, or symptoms suggesting increased pressure inside the skull.

Directions for Use

  • Ematra capsule must be taken strictly as prescribed by your doctor.
  • Swallow the capsule whole with a glass of water.
  • Do not chew, crush, break, or open the capsule.

Storage and disposal

  • Store capsules according to the manufacturer's instructions, away from direct light, heat, and moisture at controlled room temperature.
  • Keep out of reach of children and pets
  • Dispose of unused or expired medication following standard clinical waste procedures.

Quick Tips

  • Use lip balm and gentle moisturizers daily to manage dry lips and dry skin.
  • Report any sudden shortness of breath, severe headache, fever, or weight gain to your oncology team immediately.
  • Attend regular blood tests as advised to monitor blood counts, liver function, and blood lipid levels.

Dosage

Overdose

Because Ematra capsule dosage is prescribed based on body surface area, accidental overdose is uncommon. In case of an overdose, symptoms may include severe headache, nausea, vomiting, dizziness, or other symptoms associated with excessive retinoid exposure. Seek immediate emergency medical care.

Missed a Dose

If you miss a dose, take it as soon as you remember on the same day. If it is almost time for your next scheduled dose, skip the missed dose and continue your regular timing. Do not double the dose to make up for a missed capsule.

How does this medicine work?

Ematra capsule helps immature leukemia cells develop into mature white blood cells.It acts on specific receptors in these abnormal cells and removes the block that prevents them from maturing. As the cells mature, they eventually die naturally, helping control the leukemia.

Interactions

Interactions with other medicines

  • Tetracycline antibiotics, such as doxycycline or minocycline, may increase the risk of high pressure inside the skull, causing severe headache or vision problems. Tell your doctor before using them.
  • Vitamin A supplements: Avoid high doses, as they may increase the risk of side effects.
  • Tell your doctor about all prescription medicines, OTC medicines, vitamins, supplements, and herbal products you take, especially antifungals and medicines that affect the liver.

Interactions with food items

No specific food interactions have been reported.

Frequently Asked Questions (FAQs)

No. Oral Ematra capsule capsules are indicated for treating a specific type of leukemia (acute promyelocytic leukemia). The oral formulation used for APL is different from topical tretinoin products used for certain skin conditions.
Differentiation Syndrome is a severe reaction that can occur when leukemic cells differentiate rapidly during treatment. Report symptoms like fever, shortness of breath, chest pain, and sudden weight gain to your healthcare team immediately, as it requires prompt treatment.
Ematra capsule is a retinoid related to Vitamin A. Taking additional Vitamin A supplements can increase the risk of retinoid-related adverse effects, such as headache, skin dryness, and other toxic effects.
A4. Yes. Regular blood tests are necessary to monitor your blood cell counts, liver function, and blood lipid levels, particularly triglycerides, to make sure your treatment remains safe and effective during your therapy cycles.

References:

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Manufacturer Details

Brand:EMATRA

Vendor Details

Fulfillment Information: Ematra 10 MG Capsule (100) will be delivered by a licensed retail pharmacy nearest to your location. Order acceptance and fulfillment are dependent upon the verification of your doctor's valid prescription (where applicable) and the current stock of this medicine.

In Case of Any Issues Contact Us

Email Id:care@pharmeasy.in

Phone Number:7666100300

Address:D-37/1, Opp. Sandoz, TTC Industrial Area, MIDC Industrial Area, Turbhe, Navi Mumbai, Maharashtra 400703

Disclaimer

The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here  for detailed T&C.

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