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Depsonil 25mg Tablet

10 Tablet(s) in Strip
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Depsonil 25 MG Description

Deponsil tablets belong to a class of medications called tricyclic antidepressants. These are benzodiazepines derivatives. It can treat depression and adjunctive therapy for bedwetting in children of

age six years or more. The composition of Deponsil contains a chemical called imipramine. This chemical works by increasing certain chemical substances in nerve cells which helps in lightening and elevating the mood. It is best to take Depsonil tablets before going to bed to reduce its side effects. It should strictly be taken only after a valid prescription by a doctor. Tell your doctor about the history of the diseases or medications you take before using Depsonil tablets. The amount of dose and duration of treatment by Depsonil tablets will be decided by your physician to get the right amount and to control your symptoms in the right way. Though this medication does not have a habit-forming tendency, its sudden discontinuity can cause some people to develop withdrawal symptoms. In that case, always consult your doctor before discontinuing the use of Depsonil tablets. These symptoms have only been reported in patients taking high doses of this medication. The doctor will guide you by decreasing the dose of medicine step by step to prevent the appearance of any withdrawal symptoms.


Product Summary

Offer Price₹11.10
You Save₹1.96 (15% on MRP)
ContainsImipramine(25.0 Mg)
UsesDepression, Bedwetting
Side effectsAbdominal pain, Nausea, Vomiting, Dizziness, Constipation, Retention of urine
Check more medicines with composition as Imipramine(25.0 Mg)

Uses of Depsonil 25 MG

  • Depression
  • Enuresis (temporary adjunctive therapy for children more than five years)

Contraindications of Depsonil 25 MG

  • You should avoid taking this medication in the following conditions:
  • Allergy
  • Heart attack
  • If you’re taking monoamine oxidase(MAO) inhibitors

Side effects of Depsonil 25 MG

  • Dry mouth
  • Skin rashes
  • Abdominal pain
  • Nausea
  • Vomiting
  • Weakness
  • Decreased frequency of urination
  • Tachycardia (fast heart rate)

Precautions and Warnings of Depsonil 25 MG



Can I take Depsonil tablets during pregnancy?
No, it isn’t recommended to use this medication during pregnancy as it may be harmful to the baby. It isn’t prescribed until it's an emergency or life-threatening to the life of the mother. In that case, consult your doctor immediately and discuss with him for proper guidance.

Breast Feeding

Can I take Depsonil tablets while breastfeeding?
No, it is not recommended to use this medication during milking a child until it's an emergency for the life of the mother. In that case, consult your doctor immediately and discuss the issue with him for proper guidance.


Can I drive if I have taken Depsonil tablets?
No, it isn’t recommended to drive after taking Depsonil tablets. This medication can cause symptoms like drowsiness which may affect the coordinating ability of an individual. Thus it’s never advised to drive any vehicle or machine after taking Depsonil tablets.


Can I consume alcohol with Depsonil tablets?
No, it is not advised to do so. Alcohol may reduce the effectiveness of depsonil tablets, and consuming it along with alcohol leads to loss of the coordinating ability of our mind and muscles to concentrate or focus on things. Thus it is advised to avoid alcohol while taking this medication.

Other General Warnings

Talk to your doctor if
  • You are planning or about to go for surgery soon.
  • You are breastfeeding or planning to get pregnant soon.
  • You are allergic to imipramine.
  • You have a pathology of kidney or liver disease.
  • You had any recent episodes of a heart attack.
  • Your blood pressure drops beyond normal.

Mode of Action of Depsonil 25 MG

How Does It Work?

Depsonil tablets belong to a derivative of benzodiazepines. It is a tricyclic antidepressant. It chiefly works by affecting our CNS( central nervous system). It acts on two neurotransmitters in our ne...
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Directions for Use of Depsonil 25 MG

  • Depsonil tablets are taken with a glass of water.
  • They are swallowed as a whole and can be taken on an empty stomach.
  • Do not chew or crush the tablet.
  • Check the expiry date of medicine diligently before taking it.
  • Avoid taking it with alcohol or any other liquor form to get the best results.

Interactions of Depsonil 25 MG

Interactions with other medicines

  • Depsonil interaction with other medicines include -
  • Benzodiazepines may result in depression of our central nervous system
  • Aceclofenac may result in gastrointestinal bleeding
  • Acemetacin may result in gastric bleeding
  • Acarbose, when combined with imipramine, may result in decreasing the effectiveness of acarbose.

Interactions with food items

  • No such adverse interactions are known yet with Depsonil tablets.

Storage and disposal of Depsonil 25 MG

It should be stored in an airtight container so that it remains away from light, heat and moisture. It should be kept away from the reach of children. Before ingesting, the expiry date should always b...
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Dosage of Depsonil 25 MG


It can be harmful if taken in high doses; however, consult your physician immediately in accidental overdosing.

Missed a Dose

In case you miss a dose, take it as soon as possible, but if in case it gets the time for the next dose, then it’s better to ignore the missed dose and continue the dosage as it is by consuming the ne...
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Content Details


Dr. Varsha Parihar

MBBS, MD (Community Medicine)

Frequently Asked Questions (FAQs)


Q: I am a patient with liver disease. Should I take Depsonil tablets?

A: People with a history of liver disease should be cautious while using this medication. Consultation by a doctor before taking Depsonil tablets is mandatory. Dosage adjustments are needed in such patients. Regular monitoring of liver health with the help of liver function tests is also recommended from time to time to avoid chances of any injury to the liver. Consult your doctor for more information.

Q: What is the best time to take Depsonil tablets?

A: The best time to take this medication is right before bedtime. Dizziness and drowsiness are the common symptoms of this medication. Thus proper rest is recommended after you take this medicine. Thus, nighttime is the best and do take Depsonil tablets at a fixed time only to maintain adequate amounts of this medication into your system at all times. Consult your physician for more information.

Q: How much time may it take to notice the effects of Depsonil tablets?

A: It can take about 1-3 weeks before you notice the effects of Depsonil tablets. However, if you want to discontinue its use, consult your doctor first.
Product Details
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Last Updated on: 14 Feb 2022 | 09:10 AM (IST)
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