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Cofryl Cough Syrup 100ml
Cofryl Cough Syrup 100ml

Cofryl Cough Syrup 100ml

100ml Syrup in Bottle
MRP 90.75
15% OFF
Inclusive of all taxes
Non ReturnableRead More
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Cofryl Cough Syrup 100ml Description

Cofryl Syrup is a cough and cold medicine. It is used to reduce cough associated with thick sputum. It also reduces runny or stuffy nose, sneezing, watery eyes, and congestion. Cofryl Syrup is a comb

ination medicine containing diphenhydramine, ammonium chloride, and sodium citrate as active substances. If you experience drowsiness after taking this medicine, do not drive vehicles or operate machinery for 4 to 6 hours after taking the last dose. Talk to your doctor if coughing persists for more than 4 days or if you have any medical condition, or are pregnant or breastfeeding. Before starting the treatment with Cofryl Syrup, inform the doctor about your detailed medical history. Shake well before use.


Product Summary

Offer Price₹77.14
You Save₹13.61 (15% on MRP)
ContainsDiphenhydramine(14.08 Mg) + Ammonium Chloride(138.0 Mg) + Sodium Citrate(57.03 Mg)
UsesCough and cold
Side effectsDrowsiness, tiredness, nausea, vomiting
Check more medicines with composition as Diphenhydramine(14.08 Mg) + Ammonium Chloride(138.0 Mg) + Sodium Citrate(57.03 Mg)

Uses of Cofryl Cough Syrup 100ml

  • Cofryl Syrup is used to treat cough and cold, especially associated with phlegm.
  • It is also used to relieve symptoms like sneezing, runny nose, watery eyes, and stuffy nose.

Contraindications of Cofryl Cough Syrup 100ml

  • If you are allergic to diphenhydramine, ammonium chloride, sodium citrate, or any of the ingredients of Cofryl Syrup.
  • If you are taking medicines like MAO inhibitors (Selegiline, Phenelzine, etc) which are used for psychiatric illness.
  • If you have glaucoma (increased pressure in the eye which produces painful, red eyes and gradual vision loss).
  • If you have ulcers in the stomach and intestine (symptoms like vomiting, acidity, indigestion, bleeding, black stool) or any problems related to your stomach.
  • If you have prostate problems (conditions like benign prostatic hyperplasia which is characterized by difficulty in urination, frequent urge to go to urination and dribbling of urine).
  • If you have liver or kidney problems.
  • If you have an asthma attack.
  • If you are breastfeeding.
  • If you are taking other sedating antihistamines medicines like Promethazine and Chlorpheniramine.

Side effects of Cofryl Cough Syrup 100ml

  • Drowsiness
  • Dizziness
  • Tiredness
  • Nausea
  • Vomiting

Precautions and Warnings of Cofryl Cough Syrup 100ml



Can I take Cofryl Syrup during pregnancy?
If you are pregnant or think you may be or are planning for a baby, you should consult your doctor before starting Cofryl Syrup.

Breast Feeding

Can I take Cofryl Syrup while breastfeeding?
Components of Cofryl Syrup passes into breast milk thus consult your doctor before using it while breastfeeding.


Can I drive if I have consumed Cofryl Syrup?
Cofryl Syrup may cause blurring of vision and drowsiness as a side effect. It is advisable to avoid driving, operating heavy machinery or any activity that needs alertness or clear vision during the treatment.


Can I consume alcohol with Cofryl Syrup?
You should not consume alcohol while taking Cofryl Syrup as it may worsen the side effects of this medicine.

Other General Warnings

Talk to your doctor if
  • You have any breathing problems, pneumonia, asthma or any other disease.
  • You have glaucoma or fit.
  • You have any problems with your liver or kidney.
  • You consume alcohol regularly.
  • You are above 65 years of age as older individuals should be cautious while using this medicine as they are more prone to develop dizziness and urination problems with this medicine.
  • Do not use this medicine to make a child sleepy.
  • In young children, this medicine may produce excitement instead of drowsiness. So, be cautious while using it.
  • Stop using this medicine and ask a doctor if the cough lasts more than 7 days, comes back or is accompanied by fever, rash or persistent headache. These could be the signs of a serious condition.
  • Do not share Cofryl Syrup with another if they have similar symptoms.

Mode of Action of Cofryl Cough Syrup 100ml

How Does It Work?

  • Cofryl Syrup is a combination medicine containing diphenhydramine, ammonium chloride, and sodium citrate which helps in reducing cough with phlegm.
  • Diphenhydramine blocks the effects of allergic chemicals and provides relief from allergic symptoms such as running nose and watery eyes.
  • Ammonium chloride is an expectorant agent which increases the water content in the windpipe. Therefore, cough associated with thick mucus (phlegm) is relieved by making the mucus easy to expel.
  • Sodium citrate is a mucolytic agent which decreases the consistency of this mucus and makes it thin. Thus, these agents help to remove this mucus from the windpipe and lungs and improve the patient’s ...
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Directions for Use of Cofryl Cough Syrup 100ml

  • Take Cofryl Syrup as instructed by your doctor.
  • Shake well before use.
  • Use a measuring cup, spoon, or dropper for the exact quantity.
  • Do not stop taking Cofryl Syrup on your own.
  • Do not take more than the recommended dose.

Interactions of Cofryl Cough Syrup 100ml

Interactions with other medicines

  • Some medicines can affect the way Cofryl Syrup works, or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
  • Tell your doctor about all the medicines, supplements, or herbals you are currently taking or might take to avoid any possible interaction
  • Cofryl Syrup should not be used concomitantly with MAO inhibitors like Selegiline and Isocarboxazid (used for psychiatric illness). It produces a condition called serotonin syndrome which is a life-th...
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  • Concomitant use of this medicine with other anti-allergic medicines like Cetirizine, medicines like Atropine, Benztropine (used to treat travel or motion sickness, stomach cramps, Parkinson’s disease)...
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  • Other medicines like Amitriptyline, Doxepin and Ephedrine should be used with caution.

Storage and disposal of Cofryl Cough Syrup 100ml

  • Store Cofryl Syrup below 30°C in a cool and dry place.
  • Keep this medicine out of the sight and reach of children and pets.

Dosage of Cofryl Cough Syrup 100ml


In case of an overdose of Cofryl Syrup, contact your doctor immediately or visit the nearest hospital.

Missed a Dose

If you missed any dose of Cofryl Syrup, take it as soon as you remember it. If it’s time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double d...
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Content Details


Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)


Q: Can I take Cofryl Syrup with other anti-allergic medicines?

A: Cofryl Syrup already contains an anti-allergic medicine. If you use it with other anti-allergic medicine, it will increase the side effects of this medicine which can be serious and needs emergency treatment so always avoid using other medicines with it or inform your doctor about that.

Q: Can Cofryl Syrup be used for anxiety?

A: No, this medicine should not be used for anxiety. Cofryl Syrup is used to treat cough, cold and relieve symptoms like sneezing, runny and stuffy nose, watery eyes, etc.

Q: How often can I take Cofryl Syrup?

A: You should take Cofryl Syrup in doses and duration as recommended by your doctor. You should not take more than 4 doses in a day.

Q: Is Cofryl Syrup an antibiotic?

A: No, Cofryl Syrup is not an antibiotic. It is a cough and cold preparation. It is a combination of diphenhydramine which is an anti-allergic medicine, ammonium chloride which is an expectorant agent, and sodium citrate which is a mucolytic agent.
Product Details
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Last Updated on: 01 Dec 2022 | 12:48 PM (IST)

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The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here  for detailed T&C.
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