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Busag 0.5Mg Injection

1 Injection(s) in Injection

MRP350.00

262.50

25% OFF

262.5/injection (Inclusive of all taxes)
15 days return policy Read More
Offer applicable on order above ₹1000
Out of Stock

Made by

ZYDUS HEALTHCARE LIMITED

Dosage

INJECTION

Expiry

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Product Summary

Uses
Anticancer
Therapy
Anti-neoplastic
Side effects
Hot flushes and excessive sweating
Salt Content
Buserelin(0.5 Mg)
3 Step Quality
Assurance
Cash on delivery
available
NPPA
Regulated

Medical Description

Busag injection is a prescription hormonal medication that belongs to a class of drugs known as gonadotropin-releasing hormone (GnRH) agonists. It is primarily used in female fertility treatments to achieve pituitary desensitization prior to ovulation induction regimens using gonadotropins for assisted reproductive techniques (such as IVF). The medication works by temporarily controlling the release of reproductive hormones from the pituitary gland, preventing premature ovulation and helping doctors precisely time the egg retrieval process.

This medicine is supplied as a sterile nasal spray solution or a subcutaneous injection, depending on the approved formulation, and is intended for regular use under medical guidance. Follow the clinical protocols established by your fertility specialist or reproductive endocrinologist to ensure the correct hormonal balance before stimulation begins.

Treatment with Busag injection requires careful monitoring by an experienced fertility team. Throughout therapy, regular clinical evaluations are vital, including blood hormone tests and transvaginal ultrasound scans to assess follicular development and ovarian response.

Patients receiving this therapy should be fully informed about potential side effects, including temporary estrogen-lowering symptoms, hot flushes, mood changes, and the risk of ovarian hyperstimulation syndrome (OHSS) when gonadotropins are subsequently administered. Close communication with your clinic ensures that any symptoms are managed promptly and your cycle remains safe and effective.

Uses

Pituitary desensitization in preparation for ovulation induction regimens using gonadotropins in assisted reproductive technology (ART) cycles.

Contraindications

  • If you have a known hypersensitivity or severe allergic reaction to buserelin acetate, other GnRH analogues, or any of the inactive ingredients.
  • If you are pregnant or breastfeeding.
  • If you have undiagnosed abnormal vaginal bleeding.
  • If you have ovarian cysts not related to polycystic ovary syndrome (PCOS).

Side effects

Very common side effects (occurring frequently):
  • Hot flushes and excessive sweating
  • Headache and fatigue
  • Sleep disturbances (insomnia) and mood changes
  • Vaginal dryness or mild spotting
  • Local irritation (if using injection formulations)
Other reported side effects:
  • Ovarian enlargement or transient ovarian cysts
  • Nausea, abdominal discomfort, or bloating
  • Joint pain and muscle stiffness
  • Decreased libido
Serious but less common side effects:
  • Ovarian Hyperstimulation Syndrome (OHSS), particularly when combined with gonadotropins, causing severe abdominal swelling, pain, and fluid retention
  • Severe hypersensitivity or allergic reactions
  • Severe depression or emotional lability

Precautions and Warnings

Pregnancy

Pregnancy

No. Busag injection must not be used during pregnancy. If you discover you are pregnant while using this medicine, stop use immediately and contact your doctor.

Breast Feeding

Breast Feeding

No. Breastfeeding is strictly not recommended while using Busag injection due to potential risks to the nursing infant.

Driving

Driving

Use caution. Busag injection can cause side effects such as fatigue, dizziness, or headache that may impair your alertness. Avoid driving if you feel unwell.

Alcohol

Alcohol

It is best to avoid alcohol during fertility treatment, as it can interfere with your overall health, hormone balance, and treatment success.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You experience severe abdominal pain, bloating, or rapid weight gain during your stimulation cycle (signs of OHSS).
  • You notice unexplained or persistent vaginal bleeding that has not been evaluated.
  • You develop signs of a severe allergic reaction, such as rash, itching, or breathing difficulties.
  • You experience severe depressive symptoms or significant emotional changes during treatment.

Directions for Use

  • Use Busag injection exactly as prescribed by your doctor or fertility specialist, following your specific treatment cycle schedule.
  • Administer the medication via the prescribed route (e.g., nasal spray or subcutaneous injection) at the recommended times each day.
  • Do not alter your dosing schedule or stop treatment without consulting your fertility clinic.
  • Keep all scheduled appointments for ultrasound scans and blood hormone monitoring.

Storage and disposal

  • Do not store above 25°C. Do not freeze.
  • Keep the medication container in its original outer carton to protect it from light.
  • Once opened or in use, use it within the specified timeframe (typically 15 days).
  • Keep out of the reach of children and pets.
  • Ask your pharmacist or clinic about the proper disposal of used containers or expired medicine.

Quick Tips

  • Keep all scheduled clinic appointments for ultrasound scans and blood tests to closely monitor your ovarian response.
  • Report any sudden, severe pelvic pain, abdominal swelling, or rapid weight gain immediately, as these can be signs of OHSS.
  • Follow your clinic's instructions precisely regarding when to stop desensitization and start your next fertility medication.
  • Inform your healthcare providers that you are undergoing fertility treatment before any other medical procedures.
  • Store your medication correctly at room temperature (below 25°C) and protect it from light.

Dosage

Overdose

If an overdose is suspected, contact your fertility clinic or seek medical advice immediately. Symptoms of an overdose can include severe headache, dizziness, or prolonged hormonal suppression. Management involves supportive care and clinical observation under your doctor's supervision.

Missed a Dose

If you miss a scheduled dose of Busag injection, take it as soon as you remember, unless it is almost time for your next regular dose. Do not take a double dose to make up for a missed dose. Contact your fertility clinic immediately if you miss multiple doses, as this can affect your treatment cycle timing.

How does this medicine work?

Busag injection is a potent synthetic analogue of natural gonadotropin-releasing hormone (GnRH). When first administered, it stimulates the pituitary gland to release a surge of gonadotropins. However, with continuous use, it desensitizes the pituitary gland, shutting off the natural production of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This temporary downregulation prevents premature ovulation, allowing fertility specialists to control your cycle and stimulate follicle growth effectively using administered gonadotropins.

Interactions

Interactions with other medicines

  • Inform your doctor about all prescription drugs, over-the-counter medications, and herbal supplements you are taking, especially fertility treatments or hormone therapies.
  • Concomitant use with gonadotropins requires precise medical coordination to prevent complications like ovarian hyperstimulation.
  • Use caution with other hormonal medications that may interfere with your cycle desensitization.

Interactions with food items

  • No specific food restrictions are required for this medication.
  • Maintain a balanced, healthy diet and stay well-hydrated throughout your fertility treatment cycle.
  • Avoid alcohol consumption during your treatment, as it can worsen fatigue, mood swings, and potentially affect your overall well-being.

Frequently Asked Questions (FAQs)

It desensitizes the pituitary, temporarily shutting down your body's natural hormone signals. This prevents your body from releasing eggs prematurely, giving your fertility specialist total control over the timing of your IVF cycle.
OHSS is a medical condition that can occur when your ovaries respond too strongly to fertility medications like gonadotropins. Symptoms include severe abdominal pain, bloating, and nausea. Your clinic monitors you closely to prevent this.
Store it below 25°C, protect it from light in its original carton, and never freeze it. Once opened, use it within 15 days.
Contact your fertility clinic right away. Missing doses can disrupt your pituitary desensitization and affect the timing of your entire treatment cycle.
Because the drug lowers estrogen levels to prepare your body for the cycle, you may experience temporary menopausal symptoms like hot flushes or mild mood changes, which resolve after treatment ends.

References:

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Vendor Details

Fulfillment Information: Busag 0.5 MG Injection (1) will be delivered by a licensed retail pharmacy nearest to your location. Order acceptance and fulfillment are dependent upon the verification of your doctor's valid prescription (where applicable) and the current stock of this medicine.

In Case of Any Issues Contact Us

Email Id:care@pharmeasy.in

Phone Number:7666100300

Address:D-37/1, Opp. Sandoz, TTC Industrial Area, MIDC Industrial Area, Turbhe, Navi Mumbai, Maharashtra 400703

Disclaimer

The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here  for detailed T&C.

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