Bryxta 400Mg Vial Of 16Ml Suspension For Infusion
16ml Suspension For Infusion in VialMRP ₹63995.00
₹8959.30
86% OFF
Made by
ZYDUS LIFESCIENCES LIMITED
Dosage
SUSPENSION FOR INFUSION
Expiry
Product Summary
| Uses | Anti-cancer |
| Therapy | Anti-neoplastic |
| Side effects | Nausea Vomiting Weakness Diarrhoea Stomach pain |
| Salt Content | Bevacizumab(400.0 Mg/16ml) |
Assurance
available
Regulated
Medical Description
Bryxta suspension for infusion is an anticancer medication used to treat various types of cancer in adults. It contains bevacizumab, the active ingredient, which inhibits the growth of new blood vessels that supply nutrients to cancer cells.
This medication will be administered in a hospital setting by a doctor or nurse as a slow intravenous infusion. The first dose will be given over 90 minutes, which may be shortened to 60 and then 30 minutes for subsequent doses if tolerated well. Do not attempt to self-inject this medication, and ensure it is never given as an IV push or bolus, or mixed with glucose or dextrose solutions.
Bryxta suspension for infusion is strictly contraindicated for pregnant women. Women who are capable of becoming pregnant should use effective birth control during treatment and for up to 6 months after finishing Bryxta suspension for infusion. Breastfeeding must also be stopped during therapy and for at least 6 months after the final dose. This medication is not approved for use in children under 18 years of age.
Before starting treatment, please inform your doctor if you have high blood pressure, diabetes, liver or kidney problems, or a known hypersensitivity to products derived from Chinese Hamster Ovary (CHO) cells. If you have undergone major surgery, you should not take this medication for at least 28 days, or until your wound is completely healed, as it can cause serious complications with wound healing.
Uses
- Non-Small Cell Lung Cancer (NSCLC): Given as a first-line treatment alongside platinum-based chemotherapy for advanced, metastatic, or recurrent non-squamous lung cancer.
- Colorectal Cancer: Combined with fluoropyrimidine-based chemotherapy to treat metastatic cancer of the colon or rectum.
- Kidney Cancer (Renal Cell Cancer): Used as a first-line treatment in combination with Interferon alfa-2a for advanced or metastatic kidney cancer.
- Cervical Cancer: Combined with paclitaxel and cisplatin, or paclitaxel and topotecan, to treat persistent, recurrent, or metastatic cancer of the cervix.
- Brain Cancer (Glioblastoma): Used as a single agent to treat progressive glioblastoma following prior therapies.
- Breast Cancer (Metastatic): Given as a first-line treatment in combination with paclitaxel, or in combination with capecitabine when other standard chemotherapies are not appropriate.
- Used as a front-line treatment alongside carboplatin and paclitaxel.
- Used for the first recurrence of platinum-sensitive cancer in patients who have not previously received VEGF-targeted drugs.
- Combined with paclitaxel, topotecan, or pegylated doxorubicin for platinum-resistant cases where the patient has received no more than two prior chemotherapy regimens.
Contraindications
- If you are allergic to bevacizumab or any other ingredient of Bryxta suspension for infusion.
- If you are allergic to any other recombinant human or humanized antibodies. If you are not sure what these medicines are, please confirm with your doctor.
- If you are pregnant.
Side effects
- Nausea
- Vomiting
- Weakness
- Diarrhoea
- Stomach pain
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
- You have any condition that causes inflammation of the abdomen, like stomach ulcer, or diverticulitis.
- You have cervical cancer.
- You recently had or have surgery scheduled soon, including dental surgery.
- You have problems with wound healing or have an unhealed wound after surgery.
- You have high blood pressure, diabetes, blood clots or bleeding problems.
- You have infections that occur frequently.
- You have or had pain in the mouth, teeth, jaw, swelling or sores inside the mouth, numbness or a feeling of heaviness in the jaw or loose tooth.
- You have a weak blood vessel or a tear in the blood vessel.
- You have cancer of the brain or have ever coughed or spitted blood.
- You are above 65 years of age.
- You have heart disease, received X-ray therapy to your chest or have used medicines called anthracyclines (doxorubicin).
- You have previously experienced symptoms like dizziness, swelling or skin rashes, after injection.
- You develop symptoms like headaches, and changes in vision, after taking this medicine.
Directions for Use
- Bryxta suspension for infusion will be given in the hospital by your doctor or nurse.
- Do not self-inject this medicine. Follow any aftercare instructions given by the doctor or nurse.
Storage and disposal
- Store in a refrigerator at 2 - 8°C.
- Do not freeze.
- Keep out of reach of children and pets.
Dosage
Overdose
Missed a Dose
How does BRYXTA 400MG VIAL OF 16ML SUSPENSION FOR INFUSION work?
Interactions
Interactions with other medicines
- Tell your doctor about all medicines, supplements or herbals you are currently taking or might take to avoid any possible interaction.
- Bryxta suspension for infusion when used along with sunitinib malate may cause a type of anaemia called microangiopathic haemolytic anaemia (MAHA).
- Particular care should be taken if you are taking platinum-based cancer medicines (cisplatin) or taxane-based cancer medicines (paclitaxel).
References:
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Manufacturer Details
Brand:BRYXTA
Manufacturer Name:ZYDUS LIFESCIENCES LIMITED
Address:ZYDUS LIFESCIENCES LIMITED. Zydus Corporate Park, Scheme No.63,Survey No 536, Khoraj(Gandhinagar),Near Vaishnodevi Circle, Ahmedabad, Gujarat -382481
Country of Origin:India
Vendor Details
Fulfillment Information: Bryxta 400 MG/16ML Suspension For Infusion (16) will be delivered by a licensed retail pharmacy nearest to your location. Order acceptance and fulfillment are dependent upon the verification of your doctor's valid prescription (where applicable) and the current stock of this medicine.
In Case of Any Issues Contact Us
Email Id:care@pharmeasy.in
Phone Number:7666100300
Address:D-37/1, Opp. Sandoz, TTC Industrial Area, MIDC Industrial Area, Turbhe, Navi Mumbai, Maharashtra 400703
Disclaimer
The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here for detailed T&C.
