Bosutris 100Mg Bottle Of 120 Tablets

• If you have a known hypersensitivity or severe allergic reaction to bosutinib or any of the inactive excipients in the tablet formulation.
• If you have pre-existing severe liver impairment or acute liver disease.

• Diarrhea, nausea, vomiting, and abdominal pain
• Low red blood cell count (anemia), causing fatigue and weakness
• Low platelet count (thrombocytopenia), leading to easy bruising or bleeding
• Low white blood cell count (neutropenia), increasing infection risk
• Elevated liver enzymes (transaminases)
• Fatigue, weakness, and fever
• Edema (fluid retention and swelling in the limbs) and rash

• Decreased appetite and weight loss
• Headache, dizziness, and back pain
• Respiratory tract infections, cough, and shortness of breath
• Joint pain and muscle pain
• Changes in Kidney function test

• Severe liver injury and significant liver enzyme elevations
• Severe fluid retention (such as pleural effusion, pericardial effusion, or pulmonary edema)
• Severe gastrointestinal toxicity, bleeding, or perforation
• Severe myelosuppression and prolonged cytopenias
• Cardiac arrhythmias or heart dysfunction

Other General Warnings

• You have liver problems or develop yellowing of the skin or eyes, dark urine, or other signs of liver problems.
• You have a history of heart disease, fluid retention, or breathing difficulties, as careful cardiac monitoring is required.
• You experience severe diarrhea, abdominal pain, or signs of bleeding, which require prompt medical evaluation.
• You are taking antacids, stomach acid reducers, or other medications that may interact with bosutinib absorption.

• Take Bosutris tablet orally once daily exactly as prescribed by your doctor.
• Swallow the tablets whole with a glass of water; do not crush, split, or chew them.
• Take this medication with food, preferably at the same time each day.
• Continue your treatment course as long as you see clinical benefit or until your doctor advises discontinuation.

• Store the tablets at room temperature away from excessive heat, moisture, and direct sunlight.
• Keep the medication container tightly closed and out of the reach of children and pets.
• Do not keep expired or unwanted tablets; return unused medicine to your pharmacist for safe disposal.

• Keep all scheduled blood test appointments to check your liver enzymes, kidney function, and blood cell counts regularly.
• Stay well hydrated and report severe or persistent diarrhea to your doctor
• Watch for signs of unusual bruising, bleeding, or infection symptoms like fever or chills.
• Take your medication with food at the same time every day to minimize stomach upset and maintain steady drug levels.
• Inform all your healthcare providers that you are taking this medication before undergoing any scheduled surgeries or dental procedures.

Overdose

Missed a Dose

Interactions with other medicines

• Avoid strong and moderate CYP3A inhibitors (such as ketoconazole and clarithromycin), as they can increase bosutinib blood levels and the risk of side effects.
• Avoid strong and moderate CYP3A inducers (such as rifampicin, carbamazepine, or St. John's wort), as they can significantly decrease blood levels and the medicine's effectiveness.
• Proton pump inhibitors (PPIs) can reduce bosutinib absorption. Talk to your doctor before taking PPIs.

Interactions with food items

• Avoid consuming grapefruit, grapefruit juice, or Seville oranges during your treatment, as they can increase drug levels.
• Take your daily dose with food to help reduce common gastrointestinal side effects like nausea and diarrhea.
• Try to avoid alcohol consumption during treatment. Talk to your doctor about alcohol consumption during treatment, particularly if you have liver problems.