Anobliss Cream
Description
Anobliss cream is a medication used to treat conditions such as anal fissures and haemorrhoids. Its action is based on a combination of two active ingredients: lidocaine and nifedipine. Lidocaine functions as a local anaesthetic, working on the nerves to block the conduction of pain sensations for a short duration, thereby helping to reduce pain. Nifedipine, a calcium channel blocker, works by relaxing the blood vessels and muscles around the anal canal. This relaxation is crucial because the contraction of the anal sphincter and muscle spasm around the fissure often impedes the healing process.
The dual mechanism of Anobliss cream promotes better healing of the anal fissure by addressing both pain and muscle spasm. By relaxing the muscles, it allows blood to flow more easily, aiding the healing process, and by numbing the area, it provides relief from the pain and inflammation associated with these conditions. You should apply this medicine to the affected area as directed by your doctor, making sure to wash your hands thoroughly before and after application, and ideally using gloves.
While this medicine is for external use and therefore less likely to interact with other medicines, you should still consult your doctor if you are taking any other medicines for other health conditions. It is important to continue using the cream as prescribed, even if you begin to feel better, as complete healing can take time. Avoid using any other medicine on the affected area simultaneously with Anobliss cream.
Do not use Anobliss cream if you have a history of allergy to any of its contents. It is also contraindicated if you have certain medical conditions like anaemia, low blood pressure, dehydration, heart-related disorders, or if you feel an increased pressure in the brain. If you are pregnant or breastfeeding, it is advised to consult your doctor before use. If you experience any adverse effects like rectal bleeding, pain, burning sensation, or blistering, you should report this to your doctor immediately.
Anorelief cream and Fidonal cream also have lidocaine and nifedipine as their active ingredient.
Product Summary
| Offer Price | ₹115.22 |
| You Save | ₹38.41 (25% on MRP) |
| Contains | Nifedipine(0.3 %)+Lidocaine / Lignocaine(1.5 %) |
| Uses | Anal fissure |
| Side effects | Allergy at the application site, irritation on the rectal area |
| Therapy | DRUG FOR ANAL FISSURE |
Uses
Contraindications
- If you have a history of allergy to Anobliss cream or any of the content of the medicine.
- If you have certain medical conditions like anaemia, low blood pressure, dehydration, heart-related disorders etc.
- If you feel an increased pressure in the brain.
- If you are pregnant or breastfeeding.
Side effects
- Allergy at the application site
- Irritation on the rectal area
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
- You feel that symptoms are getting worse instead of getting better.
- You do not feel any improvement within a week.
- If you feel any adverse effects like rectal bleeding, pain, burning sensation, blistering etc. report to your doctor immediately.
- You should discuss your complete medical history and ongoing medications with your doctor before using this medicine.
- You are pregnant or breastfeeding.
- You should try to avoid constipation, as it may exaggerate the symptoms.
Directions for Use
- Wash your hands thoroughly. Wear gloves while using Anobliss cream to reduce the possibility of side effects.
- Lie down on your left side in a comfortable position with your left leg flat and your right leg bent with your knee in the air.
- Put a required quantity on your finger and spread the ointment around the anus and just inside the rectum.
- Remove gloves and wash hands.
- Follow the doctor's advice.
- Use this medicine for the duration your doctor has advised.
- It may take several weeks to heal the fissure, so your doctor may advise frequent follow-ups to check the clinical condition.
- Your doctor may advise adding fibre to your diet and may ask you to increase your water intake and take relaxing baths or sitz baths.
Storage and disposal
- Anobliss cream should be stored below 25°C.
- Keep it out of the sight and reach of children.
- Do not use it after the expiry date.
- Do not throw away any medicines via wastewater or household waste.
Quick Tips
- Anobliss cream is a combination medicine used in the treatment of anal fissures, anal sphincter spasms, and painful haemorrhoids.
- Do not use more than the recommended amount of this medicine or do not use it for longer periods of time than directed.
- Before starting Anobliss cream, inform your doctor if you are pregnant, planning on becoming pregnant, or breastfeeding.
- Inform your doctor if you have certain medical conditions like anaemia, low blood pressure, dehydration, heart-related disorders, etc.
- Talk to your doctor if you feel that symptoms are getting worse instead of getting better
- You should try to avoid constipation, as it may exaggerate the symptoms.
- Drinking plenty of water can help keep your stools soft and prevent constipation, which can make anal fissures worse.
Dosage
Overdose
Missed a Dose
Mode of Action
How Does It Work?
- Contraction of the anal sphincter and muscle spasm around the fissure prevents the healing process of the anal fissure. This muscle contraction is dependent on calcium.
- Nifedipine is a calcium channel blocker that works by blocking this calcium from entering the blood vessels, thus relaxing blood vessels so that blood can flow more easily and relaxing the muscles around the anal canal. ...
- Lidocaine is a local anaesthetic. It acts on nerves and blocks the conduction of pain sensations for a short duration of time. Thereby helping in reducing pain sensation.
- A combination of this medicine helps in better healing of the anal fissure.
Interactions
Interactions with other medicines
- Since this medicine is to be used externally on the skin it is less likely to interact with other medicines. However, you should always consult your doctor if you are taking other medicines for treating other health conditions....
- Avoid simultaneous application of any other medicine on the affected area after applying Anobliss cream.
Interactions with food items
Content Details
Dr. Nikita Toshi
BDS (Bachelor of Dental Surgery), WHO FIDES member
Dr. Ritu Budania
MBBS, MD (Pharmacology)
Frequently Asked Questions (FAQs)
Q: Can I take other medicines with Anobliss cream?
Q: Does Anobliss heal fissure?
Q: What should I do if I miss a dose of Anobliss cream?
Q: How should I store Anobliss cream?
References
- CDSCO [Internet]. Cdscoonline.gov.in. 2025 [cited 17th Oct 2025]
- NIFEDIPINE OINTMENT [Internet]. Medicine.umich.edu. 2025 [cited 17th Oct 2025]
- Germoloids Cream - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2025 [cited 17th Oct 2025]
- Germoloids Cream - Patient Information Leaflet (PIL) - (emc) [Internet]. Medicines.org.uk. 2025 [cited 17th Oct 2025]
- Nifedipine Gel with Lidocaine in the Treatment of Anal Fissure [Internet]. Pdfs.semanticscholar.org. 2025 [cited 17th Oct 2025]
- Lidocaine [Internet]. Pubchem.ncbi.nlm.nih.gov. 2025 [cited 17th Oct 2025]
- Nifedipine: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2025 [cited 17th Oct 2025]
- Benowitz NL, Meister W. Clinical pharmacokinetics of lignocaine. Clin Pharmacokinet. 1978 May-Jun;3(3):211-23. 2025 [cited 17th Oct 2025]
- ScienceDirect. Nifedipine [Internet]. 2025 [cited 17th Oct 2025]
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