Nifedipine+Lidocaine / Lignocaine

When should one not use Nifedipine+Lidocaine / Lignocaine

• If you have a history of allergy to Nifedipine+Lidocaine / Lignocaine or any of the content of the medicine.
• If you feel increased pressure in the brain.
• If you are pregnant or breastfeeding, unless advised by your doctor.

Common side effects of this drug are:

• Allergy at the application site
• Irritation on the rectal area

Other General Warnings

• You feel that symptoms are getting worse instead of getting better.
• You do not feel any improvement within a week.
• If you feel any adverse effects like rectal bleeding, pain, burning sensation, blistering, etc., report to your doctor immediately.
• You should discuss your complete medical history and ongoing medications with your doctor before using this medicine.
• You are pregnant or breastfeeding.
• You should try to avoid having constipation, as it may exaggerate the symptoms.
• You have medical conditions like anaemia, low blood pressure, dehydration or heart-related disorders.

How Does It Work?

• Contraction of the anal sphincter and muscle spasm around the fissure prevents the healing process of anal fissures. This muscle contraction is dependent on calcium. Nifedipine is a calcium channel blocker that works by blocking this calcium from entering the blood vessels, thus relaxing blood vessels so that blood can flow more easily and relaxing the muscles around the anal canal.
• Lidocaine is a local anaesthetic. It acts on nerves and blocks the conduction of pain sensations for a short duration of time. Thereby helping in reducing pain sensation.
• A combination of this medicine helps in better healing of the anal fissure.

Interactions with other medicines

• Since this medicine is to be used externally on the skin it is less likely to interact with other medicines. However, you should always consult your doctor if you are taking other medicines for treating other health conditions.
• Avoid simultaneous application of any other medicine on the affected area after applying Nifedipine+Lidocaine / Lignocaine.

Overdose

Missed a Dose