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Molecule Description

Ziprasidone is an atypical antipsychotic agent useful to treat certain mental disorders (like schizophrenia).

Uses of Ziprasidone

For treatment of schizophrenia (a disorder that affects a person’s ability to think, feel and behave clearly).

Contraindications of Ziprasidone

When should one not use Ziprasidone

  • Do not take this medicine if you are allergic to Ziprasidone or any ingredient of this medicine
  • Do not take this medicine if you have a history of irregular heart rhythm
  • Do not take this medicine if you have prolonged Q-T interval on ECG
  • Do not take this medicine if you have an account of recent heart attacks or heart failure

Side effects of Ziprasidone

Common side effects of this drug are:

  • Nausea
  • Vomiting
  • Sleepiness
  • Headache
  • The rise in blood sugar levels
  • Lightheadedness
  • Running nose
  • Cough
  • Weakness
  • Difficulty in breathing during sleep
  • Respiratory tract infection
  • Abnormal, uncontrolled movements
  • Vision problems

Precautions and Warnings of Ziprasidone


Can I take Ziprasidone during pregnancy?
It is unsafe to use Ziprasidone during pregnancy. Take only when specifically prescribed by your doctor.

Breast Feeding

Can I take Ziprasidone while breastfeeding?
It is unsafe to use Ziprasidone during breastfeeding. Take if found essential by your doctor.


Can I drive if I have consumed Ziprasidone?
Taking this medicine may cause unsteadiness, blurred vision or headache. It is not recommended to drive or operate heavy machinery when taking this medicine.


Can I consume alcohol with Ziprasidone?
Alcohol may worsen the side effects. It is not advised to consume alcohol when taking this medicine.

Other General Warnings

Talk to your doctor if
  • You have diabetes
  • You have any allergy or any significant changes in behaviour
  • You have heart-related problems

Mode of Action of Ziprasidone

How Does It Work?

Ziprasidone regulates certain chemical activities within the brain, which are responsible for thoughts, behaviour and mood.

Interactions of Ziprasidone

Interactions with other medicines

  • It may reduce the effects of Levodopa and Dopaminergic medicines given to patients of Parkinson’s disease
  • It may cause altered metabolism if given with Carbamazepine and Ketoconazole
  • Metoclopramide
  • Saquinavir
  • Muscle relaxants
  • Cough syrups
  • Sotalol
  • Tacrolimus
  • Quinidine
  • Moxifloxacin

Interactions with food items

No information is available on interactions of Ziprasidone when taken with food, consult your doctor or pharmacist for further details.

Dosage of Ziprasidone


Ziprasidone overdose can lead to symptoms such as sedation, slurred speech, an increase in blood pressure, trouble in breathing, tremors, unconsciousness and anxiety. If you suspect an overdose, seek emergency medical care immediately.
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Missed a Dose

Take the missed dose as early as you remember. Skip the missed dose if it is already time for the next dose. Do not take extra medicine to compensate for the missed dose.

Content Details


Dr. Arpit Verma

MBBS, MD (Pharmacology)


Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)


Q: What should be discussed with my health care provider before taking Ziprasidone?

  • Tell your doctor if you have diabetes
  • Any allergy
  • Any significant changes in behaviour
  • Heart-related problems
  • Pregnancy

Q: Are there any precautions that I must consider?

  • One must avoid alcohol when taking this medicine
  • Do not drive or operate heavy machinery
  • This medicine leads to increased sleepiness, impaired judgment, thinking ability and altered control over body movements
  • It may cause symptoms of high blood glucose even if you do not have diabetes
  • Inform your doctor if you experience any unusual muscle movements in the arms, jaws, tongue, limbs, etc.
  • Inform your doctor if you are pregnant or planning to be pregnant
Last Updated on: 05 Oct 2020 | 10:47 PM (IST)

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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts. Please click here for detailed T&C.
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