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Valsartan

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Molecule Description

Valsartan belongs to a class of medicines known as Angiotensin II Receptor Antagonists, which help to control high blood pressure and reduces the chance of heart failure in the future.

Uses

Mild to moderate hypertension.

Contraindications

When should one not use Valsartan

  • Do not take this medicine if you are:
  • Pregnant
  • Allergic to Valsartan
  • Suffering from liver disease
  • Diabetic or with an impaired kidney function

Side effects

Common side effects of this drug are:

  • Swollen face, lips, tongue or throat
  • Difficult to swallow or breathe
  • Low blood pressure
  • Dizziness
  • Low blood pressure
  • Decreased kidney function

Precautions and Warnings

Pregnancy

Pregnancy

Valsartan is not recommended in early pregnancy as it may cause serious harm to your baby if used at that stage. It is advised to consult the doctor.

Breast Feeding

Breast Feeding

This medicine is not advised for breastfeeding mothers.

Driving

Driving

This medicine is not known to affect your driving ability. If you experience dizziness or drowsiness with Valsartan, avoid driving.

Alcohol

Alcohol

Be careful while drinking alcohol along with this medicine as it may cause a sudden drop in the blood pressure level.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You are known to have narrowing or blockage of the blood vessels of kidneys or recently had a kidney transplant
  • You have liver disease
  • You suffer from heart failure with or without kidney disorders
  • You have high blood pressure and diabetes, related to kidney problems
  • You feel swelling of the face, lips, throat, tongue, excessive vomiting or diarrhea

Mode of Action

How Does It Work?

Angiotensin II is a substance in the body that causes the blood vessels to tighten, thus causing an increase in your blood pressure level. Valsartan works by obstructing the effect of Angiotensin II. As a result, blood vessels relax and blood pressure level is lowered down to normal.

Interactions

Interactions with other medicines

  • All enzyme inhibitors (ACE-inhibitors like Ramipril, Enalapril, etc.)
  • Azathioprine
  • Lithium
  • Aspirin
  • Aliskiren
  • NSAIDs (Non-Steroidal Anti-Inflammatory Drugs such as Ibuprofen, Naproxen, etc.) may decrease the effectiveness of Valsartan
  • Medicines which are known to  increase potassium levels like Diuretics

Interactions with food items

Avoid high potassium-containing foods. A low-salt diet is preferred. High levels of potassium in your food will cause irregular heartbeat, tingling of the extremities, weakness, confusion, or a sense of heaviness in the legs.

Dosage

Overdose

Overdose symptoms would be low blood pressure and fast heartbeats. In a few cases, a slow heart rate could also be encountered. Dizziness, loss of consciousness, and sudden acute kidney failure may also occur. Seek emergency medical attention immediately.

Missed a Dose

Take the missed dose as early as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosage schedule. Do not take a dosage twice to compensate for a missed one.

Frequently Asked Questions (FAQs)

It is given for oral intake and usually prescribed as per standard dose. To be strictly taken under a physician’s guidance. May or may not be taken with food but it is advised to take this medicine at a fixed time every day.

Try to avoid getting up suddenly from a sitting or lying position or you may feel dizzy. Get up slowly and stabilize yourself to prevent a fall.

Tell your doctor if you are allergic to Valsartan or any other medicine of the same group (e.g., Telmisartan, Olmesartan, Losartan, etc.). If you have diabetes, do not use Valsartan together with any medication that contains Aliskiren, especially if you have kidney disease. To make sure you can safely take Valsartan, tell your doctor if you have any history of liver, kidney disease or heart ailments and inform about all your ongoing medications.

It would be best if you stored Valsartan in a cool, dry place away from sunlight and heat.

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