Tobramycin

• Used to treat bacterial infection of the skin, heart, stomach, brain, spinal cord, lungs and urinary tract
• Used to treat Infection in eye
• Used in the treatment of cystic fibrosis

When should one not use Tobramycin

• Do not take this medicine if you are allergic to this medicine ingredient
• Taking with Ethacrynic Acid, Furosemide, Mannitol or Urea
• Taking the medicines that may damage your kidney

Common side effects of this drug are:

• Black, tarry stools
• Chest pain
• Chills
• Tinnitus (continuous ringing or buzzing noise in the ear)
• Painful or difficult urination
• Tiredness
• Diarrhea
• Headache
• Weakness
• Shortness of breath
• Sore throat; sores, ulcers or white spots on lips or in the mouth
• Swollen glands
• Hearing loss
• Unusual bleeding or bruising

Other General Warnings

• Hearing problems (noises in the ears and dizziness)
• Kidney problems
• Difficulty in breathing with wheezing or coughing
• Chest tightness
• Blood in your sputum (the substance you cough up)
• Muscle weakness that lasts or becomes worse over time, a symptom mostly related to conditions like myasthenia or Parkinson’s disease

How Does It Work?

Interactions with other medicines

• Some of the medicines which may interact with Tobramycin:
• Cephaloridine, Cephalosporins (such as Ceftizoxime), Cisplatin, Colistin, Cyclosporine, Fludarabine, loop diuretics (such as Furosemide, Ethacrynic Acid), Methoxyflurane, Nitrosoureas (such as Carmustine), NSAIDs (such as Ibuprofen), Polymyxin B, Vancomycin or Viomycin, nondepolarizing muscle relaxants (e.g. Atracurium) or Succinylcholine, etc. may increase the risk of Tobramycin side effects such as increased risk of kidney damage or hearing loss
• Beta-lactam antibiotics such as Penicillin, Imipenem, Sultamicillin may decrease Tobramycin effectiveness

Interactions with food items

Overdose

Missed a Dose