Ticagrelor

• Heart attack
• To reduce the risk of stroke in patients having a history of heart attack or chest pain
• In patients who have stents inserted (i.e. to prevent blocking of the stent with a blood clot)

When should one not use Ticagrelor

• You are allergic to Ticagrelor
• You have any active bleeding currently
• You have a history of intracranial bleeding or history of bleeding from ulcer in the stomach or intestine
• In patients in whom aspirin is contraindicated

Common side effects of this drug are:

• Allergic reaction like fever, chills, rash, hives, breathing difficulty, swelling over your face, lips, throat
• Bleeding from an unusual site (mouth, nose, rectum, vagina, gums)
• Easy bruising, pinpoint rash on the skin
• Easy weakness and fatigue
• Red or pink urine
• Diarrhea
• Itching
• Fainting
• Blood in the stool (red or black ), cough or vomit (coffee coloured vomit)
• Shortness of breath
• Sudden numbness or weakness on one side of the body with problems in speech, balance and vision and excessive headache indicating of stroke (serious side effect)
• Yellowing of eyes or skin, weakness, fever and anorexia (suggestive of liver problems)

Other General Warnings

• Have any liver disease
• Have any lung problem or difficulty in breathing
• Had any recent bleeding or injury or surgery or dental procedure
• Have an upcoming surgery
• Have a high uric acid level
• A sudden stoppage of medicine can increase the risk of heart attack or stroke

How Does It Work?

Interactions with other medicines

• Non-Steroidal Anti-Inflammatory Drugs like Naproxen, Ibuprofen, Diclofenac
• Taking medicine that contains more of Aspirin. Since Aspirin is already advised along with Ticagrelor. Consuming combination medicine that contains Aspirin can cause its overdose and result in bleeding
• Antibiotics like Clarithromycin
• Antiviral medicine (Anti HIV medicine like Ritonavir and Atazanavir)
• Antifungal medicine like Ketoconazole
• Anti-seizure medications
• Tuberculosis medicines like Rifampicin
• Do not take Ticagrelor if you are already taking blood thinner medicines like Warfarin

Interactions with food items

Overdose

Missed a Dose