Telmisartan+Metoprolol

When should one not use Telmisartan+Metoprolol

• If you have any allergic reaction to Metoprolol, Telmisartan or any of the ingredient of Telmisartan+Metoprolol
• If you are suffering from heart problems like heart block, heart failure or sick sinus syndrome (abnormal heart rhythms)
• If you have a specific type of angina called Prinzmetal's angina
• If you have reduced blood supply to your limbs (peripheral arterial disease)
• If you have asthma or chronic obstructive pulmonary disease (COPD)
• If you are suffering from an adrenal gland tumour (phaeochromocytoma)
• If you have a condition called metabolic acidosis (increased acidity in your body or are on medicines to treat irregular heart rhythm like disopyramide)
• If you have diabetes associated with frequent low blood sugar levels
• If you are suffering from low blood pressure (hypotension)
• If you are in the second or third trimester of pregnancy
• If you have blockage of any duct that carries bile from the liver to gallbladder (obstructive biliary disorders) or severe liver disease
• If you have diabetes and you are taking Aliskiren

Common side effects of this drug are:

• Dizziness
• Headache
• Nausea
• Vomiting
• Stomach pain
• Tiredness
• Slow heart rate
• Low blood pressure

Other General Warnings

• You have asthma
• You have diabetes, caution is required. Metoprolol may cause low blood sugar levels and also change the body's response to low blood sugar. You may experience warning signs of low blood sugar such as an increase in heart rate, sweating, hunger pangs, headache, etc.
• You have a tumour of adrenal gland tissue (Pheochromocytoma)
• You have an overactive thyroid (a condition when the thyroid gland produces too much of the thyroxine hormone)
• You are suffering from psoriasis
• You have a circulation related problem in the toes, arm, legs or fingers
• You are suffering from a type of chest pain (Prinzmetal's angina)
• You recently had any heart attack, chest pain or heart surgery
• You have kidney disease or have had a kidney transplant or liver disease
• You are known to have narrowed or blockage of the blood vessels of one or both kidneys
• You develop diarrhoea or vomiting, this dehydration can result in low blood pressure, have an adequate amount of water and fluids
• You are suffering from low blood pressure (hypotension)
• You have a high level of potassium in your blood
• You are taking medicines like Ramipril and Lisinopril

How Does It Work?

• Metoprolol works by slowing the heart rate and relaxing blood vessels and reduces high blood pressure.
• Angiotensin II is a substance produced in the body which causes the narrowing of blood vessels. It leads to an increase in blood pressure.
• Telmisartan prevents the binding of Angiotensin II to its receptors and causes the blood vessels to relax and lowers the blood pressure.

Interactions with other medicines

• Telmisartan+Metoprolol contains Metoprolol and Telmisartan, if any interactions seen with these two components when taken alone, may occur with this combination
• Do not take it with medicines like Amiodarone, Disopyramide or painkillers like Indomethacin, Sulindac, Diclofenac and Foctafenine as these can decrease the effect of this medicine
• If you have diabetes, dose adjustment may be needed as this medicine can cause a drop in blood glucose levels and close glucose monitoring is advised
• Medicines used to treat high blood pressure and benign prostatic hyperplasia (Prazosine, Tamsulosin, Terazosin and Doxazosin).
• If you have diabetes and you are on Aliskiren, do not take this medicine
• Caution is needed if you are taking Fluoxetine, Lithium, Paroxetine, Bupropion, Thioridazine (medicines for psychiatric illness), Diphenhydramine, Hydroxychloroquine and Mefloquine
• Medicines used to treat acidity or ulcers (antacids) like Cimetidine
• Medicines used to treat heart problems (Digoxin)
• Medicines used to treat depression and Parkinson's disease (Monoamine Oxidase inhibitors)
• Medicines used to lower down the blood pressure (Clonidine, Guanfacine, Moxonidine, Methyldopa and Rilmenidine)
• Medicines used to treat migraine (Ergotamine) or Nitroglycerine
• General anaesthetics or local anaesthetic (Lidocaine)
• Medicines that may increase blood potassium levels like salt containing potassium and potassium-sparing diuretics
• Blood thinners like Warfarin and Heparin
• Immunosuppressives (Cyclosporin or Tacrolimus)
• Medicines used to treat infections like Trimethoprim, Rifampicin or Terbinafine
• Medicines known as Diuretics (water pills) used to treat high blood pressure like Furosemide and Hydrochlorothiazide

Interactions with food items

Overdose

Missed a Dose