Quetiapine

Molecule Description

Quetiapine is an antipsychotic medicine used in the treatment of schizophrenia,

mood swings (bipolar disorder) and depressive disorder.

Uses

Contraindications

Side effects

Precautions and Warnings

Uses of Quetiapine

Mental disorder that affects a person’s ability to think or behave properly (Schizophrenia)
Mood swings ranging from feeling low (depression) to very high (maniac) – a condition known as bipolar disorder
To treat patients suffering from major depressive disorders (MDDs) who are not responsing to regular medicines
For prevention of repeat episodes of depression

Contraindications of Quetiapine

When should one not use Quetiapine

If you are allergic to the medicine or any other substances used to make this medicine
Do not take Quetiapine if you are taking any of the following:
If you are taking some medicines for HIV (Protease inhibitors – Atazanavir, Lopinavir)
If you are taking medicines used to treat fungal infections (Ketoconazole, Posaconazole, Itraconazole, etc.)
If you are taking Erythromycin or Clarithromycin (for infections)
If you are taking Nefazodone (for depression)

Side effects of Quetiapine

Common side effects of this drug are:

Dizziness, weakness, feeling sleepy
Symptoms of discontinuation when you stop taking Quetiapine (nausea, vomiting, diarrhea, feeling irritated)
Low blood pressure, swelling of hands and legs
Unpleasant dreams & nightmares, suicidal thoughts
Blurred vision, difficulty in speaking
Rapid heartbeat
Weight gain, increased appetite
Changes in the blood levels of following – fats, triglycerides, thyroid hormones, decreased blood cells, increased blood sugar levels, elevated liver enzymes, high prolactin levels
Seizures (fits)
Combination of flu-like symptoms, fever, sore throat
Unpleasant sensation in the legs (restless legs syndrome)
Difficulty in passing urine
Fainting
Stuffy nose
Allergic symptoms - itching, hives, rash and swelling of lips, face, throat, etc.
High fever, muscle stiffness, fever, drowsiness (neuroleptic malignant syndrome)
Yellowing of the skin (jaundice), liver disease
Worsening symptoms, e.g. anxiety, panic attacks, irritability, agitation, aggressiveness, etc.
Formation of blood clots (severe)
Low body temperature (hypothermia)
A combination of any 3 of the following – increase in fat around abdomen, decrease in good cholesterol (HDL-C), high blood pressure, elevated blood glucose and triglyceride levels (metabolic syndrome)

Precautions and Warnings of Quetiapine

Pregnancy

Can I take Quetiapine during pregnancy?

If you are pregnant or think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before Quetiapine. Though there is no evidence of the potential to harm the baby, Quetiapine is recommended to be used in pregnant women only if no alternatives exist.

Breast Feeding

Can I take Quetiapine while breastfeeding?

Studies indicate that Quetiapine is secreted in breast milk, but the quantity is not established. Hence, it is recommended not to continue with the medication if you are breastfeeding, to prevent any harmful effects to the baby.

Driving

Can I drive if I have consumed Quetiapine?

Do not drive while on Quetiapine as it acts on the brain and you may feel drowsy.

Alcohol

Can I consume alcohol with Quetiapine?

Be careful of how much alcohol you drink. This is because the combined effect of Quetiapine and alcohol can make you sleepy, as alcohol also affects the brain. Only mild drinking may be permitted.

Other General Warnings

Talk to your doctor if

Low blood pressure
Brain stroke, especially if you are an elderly patient (above 65 years)
Any liver problems
Fits (seizures)
Diabetes or at risk

Mode of Action of Quetiapine

How Does It Work?

It works by helping to restore the balance of certain natural substances (neurotransmitters) such as Serotonin and Dopamine in the brain. Increased levels of these substances may cause depression or m...

Interactions of Quetiapine

Interactions with other medicines

Anti-seizure medications (Phenytoin, Carbamazepine, etc.)
Medicines used to treat high blood pressure (BP)
Sleeping pills (Barbiturates)
Other anti-psychotic or anti-depression medicines (Lithium, Thioridazine)
Medicines for heart diseases
Medicines that may block your nerve impulses (anticholinergics-Atropine, Dicyclomine, etc.)
Antibiotics or any other medicines used to treat infections
Medicines used to treat HIV/ AIDS (Protease inhibitors – Atazanavir, Lopinavir)
Medicines used to treat fungal infections (Ketoconazole, Posaconazole, Itraconazole, etc.)
Antibiotics (Erythromycin, Clarithromycin, etc.)
Nefazodone (for depression)

Interactions with food items

Quetiapine may interact with food, and you are advised to take your tablets at least one hour before a meal or before going to bed.

Dietary Restrictions of Quetiapine

Do not drink grapefruit juice while you are taking Quetiapine.

Dosage of Quetiapine

Overdose

The effects of an overdose may be lethal and need immediate medical attention. The symptoms of overdose can be – seizures, breathing difficulty, shallow breathing, rapid heart rate, confusion, drowsin...

Missed a Dose

If you miss a dose, take medicine when you remember the missed dose. If it is almost time for your next dose (less than 6-8 hours), do not take the missed dose and continue with the regular dosing sch...

Content Details

WRITTEN BY

Dr. Mahesh Muthe

MBBS

REVIEWED BY

Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)

Q: Are there any other precautions I need to follow while taking Quetiapine?

Do not stop the medicine suddenly. It may cause discontinuation symptoms like sleeplessness (insomnia), dizziness, irritability, nausea, vomiting, headache or diarrhea
Speak to your doctor if you do not want to take this medicine and he will reduce the dose gradually
Self-medication and adjusting the dose on your own is strictly not recommended with this medicine

References

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Last Updated on: 05 Oct 2020 | 10:47 PM (IST)

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परिचय: “बिना मशरूम के खाना बिना बारिश के दिन जैसा होता है”। मशरूम या अगरिकस बिस्पोरस न तो सब्ज़ी है और न ही फल, बल्कि यह खाई जाने वाली एक फंगस है। बाजार में इसकी अलग-अलग किस्में (ताजा व सूखा) उपलब्ध हैं; जिसमे ओएस्टर , पोर्सिनी और बटन सबसे आम किस्में हैं। आमतौर पर, मशरूम

आंवला (Gooseberry in Hindi) के उपयोग, फ़ायदे और न्यूट्रिशनल वैल्यू

परिचय वानस्पतिक नाम एम्ब्लिका ऑफिसिनैलिस आमतौर पर आंवला को इंडियन गूजबेरी (भारतीय करौंदा) कहा जाता है। इन पेड़ों की बेरी को इनके औषधीय गुणों के कारण औषधीय फार्मूलेशन में प्रयुक्त किया जाता है। आंवला के पेड़ पर छोटी बेरीज़ होती हैं जो गोल और पीले-हरे रंग की होती है। इसके कई स्वास्थ्य फ़ायदों के कारण

केला (Banana in Hindi): उपयोग, लाभ और न्यूट्रिशनल वैल्यू

परिचय: “एक दिन में एक केला (बनाना) खाने से मेरा एंडोर्फिन लेवल बना रहता है।” बनाना (मूसा प्रजाति) या केला एक लंबा, पीला फल है जो वास्तव में एक बेरी है। यह मुसासी (मुसासेई) परिवार से संबंधित हैं और इसमें मूसा एक्यूमिनाटा, मूसा बालबिसियाना आदि किस्में शामिल हैं। यह दक्षिणी एशिया के उष्णकटिबंधीय क्षेत्रों (ट्रॉपिकल

सौंफ (Fennel Seed in Hindi) : उपयोग, लाभ और न्यूट्रिशनल वैल्यू

परिचय: सौंफ (फेनल सीड) का वैज्ञानिक नाम फीनीकुलम वल्गारे है और यह एपोकिनेसी परिवार से संबंधित एक सुगंधित पौधा है।1 सौंफ (फेनल सीड) की एक अलग आकृति, आकार और रंग होता है; यह लंबी, पतली होती है और हल्के हरे या भूरे रंग की होती है। सौंफ (फेनल सीड) का पौधा इसके बीजों, पत्तियों और

ड्रैगन फ्रूट (Dragonfruit in Hindi): उपयोग, लाभ और न्यूट्रिशनल वैल्यू

ड्रैगन फ्रूट कैक्टस प्रजाति का फल होता है जिसके स्वास्थ्य से जुड़े कई लाभ होते हैं जैसे कि रक्त शर्करा (ब्लड शुगर) के जोखिम को कम करना, पाचन (डाइजेशन) में मदद करना आदि। यह एक ड्रैगन की तरह दिखता है और इस वजह से इसका यह नाम पड़ा। अब आप सोच रहे होंगे कि इस

तेजपत्ता (Bay Leaves in Hindi)– उपयोग, फायदे और न्यूट्रिशनल वैल्यू

परिचय तेजपत्ता सिनामोमम तमाला नामक पौधे की सूखी पत्तियां होती हैं। यह सिनामोमम वंश के लौरेसी परिवार का पौधा होता है जिसकी 270 प्रजातियां हैं और प्रमाणिक रूप से ये सभी एशिया और ऑस्ट्रेलिया में पाई जाती हैं। तेजपत्ता को भारतीय बे-लीफ़ भी कहा जाता है जो छोटे सदाबहार या बारहमासी वृक्ष पर होते हैं

नाशपाती (Pear in Hindi): उपयोग, फ़ायदे, न्यूट्रिशनल वैल्यू आदि!

परिचय: नाशपाती का वैज्ञानिक नाम पायरस कमिनिस एल है। यह रोज़ेसी फ़ैमिली से संबंधित है। नाशपाती को सेब के बाद सबसे ज्यादा पौष्टिक फल माना जाता है। यह विटामिन आहार फाइबर, एमिनो एसिड, एवं क्वेरसेटिन का बढ़िया स्रोत होता है। नाशपाती अपने मिठास, सुगंध, कुरकुरेपन और ख़ास खुशबू के लिए जाना जाता है। मूल रूप

सीए 125 टेस्ट (महिलाओं के लिए) (CA 125 Test (For Women) in Hindi): क्या है, खर्च, नॉर्मल रेंज, कैसे होता है, क्यों और कब

विवरण: सीए 125 टेस्ट का इस्तेमाल शरीर में सीए 125 प्रोटीन के स्तर का पता लगाने के लिए किया जाता है, जो कैंसर का पता लगाने में मददगार साबित हो सकता है। नमूना प्रकार खून उपवास \ खाली पेट रहना जरूरी: नहीं उपनाम: कैंसर एंटीजन 125 टेस्ट, सीए-125 ट्यूमर मार्कर, सीए 125 ब्लड टेस्ट। सीए

सीरम इलेक्ट्रोलाइट्स (Serum Electrolytes): क्या है, खर्च, नॉर्मल रेंज, कैसे होता है, क्यों और कब

विवरण: एक सीरम इलेक्ट्रोलाइट परीक्षण आपके खून में मौजूद इलेक्ट्रोलाइट्स के स्तर को मापने की एक विधि है। इससे किडनी या दिल की समस्याओं जैसी कई बीमारियों का निदान करने में मदद मिल सकती है। आपको यह परीक्षण कितनी बार लेना चाहिए? कोई विशिष्ट आवृत्ति नहीं है। डॉक्टर आमतौर पर सीरम इलेक्ट्रोलाइट परीक्षण को मेटाबोलिक

हींग (Asafoetida in Hindi): उपयोग, फ़ायदे, न्यूट्रिशनल वैल्यू और अन्य बातें!

परिचय दुनिया के बहुत से हिस्सों में, हींग (ऐसाफ़ेटिडा) को खाने का स्वाद बढ़ाने वाले तत्व के रूप में और विभिन्न प्रकार की बीमारियों का पारंपरिक रूप से उपचार करने के लिए किया जाता है। हींग (फ़ेरुला ऐसाफ़ेटिडा), एक ओलिओ-गम-रेज़िन है जो अंबेलीफेरा फ़ैमिली के फ़ेरुला पौधों के तनों में बनती है। फ़ेरुला के पौधे

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