Permethrin

Description

Permethrin is an antiparasitic molecule widely used for the treatment of scabie

s, a skin infestation caused by the mite Sarcoptes scabiei. It works by paralysing and killing the mites and their eggs, helping relieve symptoms such as intense itching and a pimple-like rash. Permethrin is intended for external use only and should be applied only to unbroken skin as directed by a doctor or pharmacist. Care must be taken to avoid contact with the eyes, mouth, and mucous membranes. Washing hands before and after use ensures proper application and prevents the spread of infection.

Uses

Contraindications

Side effects

Precautions and Warnings

Uses

Infections of head louse (pediculus humanus capitis)
Scabies (skin itching and rashes caused by mites)

Contraindications

When should one not use Permethrin

In patients with known allergic reaction to Permethrin.

Side effects

Common side effects of this drug are:

Skin and scalp irritation such as itching, swelling, stinging, mild burning, tingling, numbness and redness
Any symptoms of a serious allergic reaction, especially of the face/ tongue/ throat, severe dizziness, trouble breathing (rare, but serious)

Precautions and Warnings

Pregnancy

Can I take Permethrin during pregnancy?

Data available on usage of Permethrin in pregnant women is inadequate. Pregnant women are advised to use Permethrin only if it is necessary and alternatives are not available.

Breast Feeding

Can I take Permethrin while breastfeeding?

It is unknown if Permethrin passes into breast milk, but it is advisable not to use the medicine while breastfeeding. Do not decide on your own. Consult your doctor before breastfeeding.

Driving

Can I drive if I have consumed Permethrin?

As Permethrin is a topical cream rinse used for external application, it is unlikely to affect the ability to drive.

Alcohol

Can I consume alcohol with Permethrin?

Interaction with alcohol is not known but it is advised not to drink too much alcohol while on Permethrin.

Mode of Action

How Does It Work?

This medicine works by attacking the nervous system of lice and paralyzing them. It also kills head lice and their eggs attached to your scalp. It can be used for all age groups starting from 6 months...

Interactions

Interactions with other medicines

This medicine may interact with Cortisol.

Interactions with food items

No specific food interactions are available.

Dietary Restrictions

You should not use this medicine if you are allergic to it
Permethrin is for external use so do not consume it as it may be life-threatening
Avoid contact with eyes, mouth and tongue

Dosage

Overdose

As it is a topical cream rinse, overdose is not expected. But if you apply the cream more times than necessary, allergic reactions such as rashes, itching, redness may develop. Call your doctor if the...

Missed a Dose

Permethrin cream rinse comes in a container and should be used wholly once opened. If you are prescribed to use again, you need to buy a new box.

Content Details

WRITTEN BY

Dr. Ravi Kakarla

MBBS, MBA

REVIEWED BY

Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)

Q: Are there any special precautions or warnings for using Permethrin?

A: You should not use Permethrin if you are allergic to it. Permethrin is for external use only so do not consume it as it may be life-threatening. Avoid contact with eyes, mouth and tongue.

Q: What is Permethrin used for?

A: Permethrin is used to treat scabies, a skin infestation that causes itching and rash due to tiny mites under the skin. It kills the mites by paralysing them, helping clear the infection. It is applied externally on the skin as directed. Using it correctly ensures the best results. Always follow your doctor’s instructions for proper application.

Q: Can Permethrin cause side effects?

A: Some people may experience mild redness, tingling, itching, or dryness after applying. These effects are usually temporary and often improve as the mites die. If you notice severe irritation, rash, or worsening symptoms, consult your doctor.

Q: How long does it take for Permethrin to work?

A: Permethrin starts working quickly, but itching may continue for a few weeks as the skin heals. This does not mean the treatment failed. Your doctor may recommend a second application if needed. Avoid scratching to prevent skin damage or infection. Consult your doctor if symptoms persist or worsen after treatment.

Q: In what dosage forms is Permethrin available?

A: Permethrin is available in several forms depending on the condition being treated. The most common form is a cream used for scabies. It is also available as a lotion or cream rinse for treating head lice. Some regions may offer topical solutions or sprays for specific uses. Always use the form and strength recommended by your doctor.

References

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Last Updated on: 05 Dec 2025 | 07:53 PM (IST)

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Disclaimer

The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here for detailed T&C.