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molecule

Milnacipran

Molecule Description

Milnacipran is used in the treatment of chronic pain caused by Fibromyalgia alt

hough it works as an antidepressant.

uses

Uses of Milnacipran

  • Chronic pain caused by Fibromyalgia (that affects the muscles, tendons, ligaments and supporting tissues)
  • Depression
contraindications

Contraindications of Milnacipran

When should one not use Milnacipran

  • It is advisable to avoid taking Milnacipran in:
  • If you are allergic to this medicine
  • Child below 18 yrs of age
  • Kidney disease
  • Heart disease, high BP
  • Blood cell disorder e.g. sickle cell or haemophilia
  • Glaucoma
  • Low sodium levels in the body
  • Problems in urination
  • Bipolar disorder
  • Liver disorder
  • Convulsions or epilepsy
sideEffects

Side effects of Milnacipran

Common side effects of this drug are:

  • Nausea, vomiting
  • Dry mouth
  • Constipation
  • Increased sweating
  • Headache
  • Dizziness
  • Insomnia
  • High blood pressure
  • Serious side effects:
  • Allergic symptoms - itching, hives, rash, swelling of lips, face, etc.
  • Liver complaints – stomach pain, nausea, vomiting, jaundice, dark urine
  • Blurred vision, tunnel vision
  • Convulsion
  • Easy bruising, bleeding
  • Manic episodes – increased energy, extreme happiness, talkative etc.
  • High serotonin signs - hallucination, fever, agitation, nausea, vomiting, diarrhea, fainting, etc.
  • Low sodium signs – headache, confusion, slurred speech, loss of coordination, severe weakness, etc.
  • High BP – severe headache, chest pain, breathlessness, irregular heartbeats, nosebleed, etc.
precautionsAndWarnings

Precautions and Warnings of Milnacipran

pregnancy

Pregnancy

Q:
Can I take Milnacipran during pregnancy?
A:
It is advisable to avoid taking Milnacipran during pregnancy. It may affect the unborn baby.
breastfeeding

Breast Feeding

Q:
Can I take Milnacipran while breastfeeding?
A:
It is not recommended in breastfeeding. It is still not known if it passes into breast milk. Doctor's consultation is advised.
driving

Driving

Q:
Can I drive if I have consumed Milnacipran?
A:
It may impair your thinking or reactions and this in turn, may affect your ability to drive. Be cautious while driving if you are on this medication.
alcohol

Alcohol

Q:
Can I consume alcohol with Milnacipran?
A:
Milnacipran may cause excessive drowsiness and calmness with alcohol. It may worsen existing liver damage. It is advised to avoid excess intake of alcohol with this medicine.
otherGeneralWarnings

Other General Warnings

Talk to your doctor if
  • You notice abrupt mood changes or develop suicidal thoughts
  • You have any liver, kidney or heart problems
  • You have any psychiatric conditions or you're on a medication for that
modeOfAction

Mode of Action of Milnacipran

How Does It Work?

This medicine is Serotonin-Norepinephrine Reuptake Inhibitor (SNRI). It works by helping to restore the balance of certain natural substances present in the brain (neurotransmitters), thereby reducing...
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interactions

Interactions of Milnacipran

Interactions with other medicines

  • Narcotic pain medicine, sleeping pills, muscle relaxants, medicine for anxiety, depression, fits, etc.
  • Certain medicine, when taken along with Milnacipran, can cause Serotonin syndrome – e.g., Medicine for Parkinson’s disease, migraine, ADHD, etc.
  • Blood thinners e.g., Warfarin

Interactions with food items

No adequate information.
dosage

Dosage of Milnacipran

Overdose

  • The symptoms of overdose can be – slow heart rate, weak pulse, fainting, slow breathing, etc.
  • Seek medical emergency help in case of overdose

Missed a Dose

If you miss a dose, take medicine when you remember the missed dose. If it is almost time for your next dose, don’t take the missed dose and go back to the regular dosing schedule. Do not take a doub...
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Content Details

WRITTEN BY
REVIEWED BY
doctor

Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)

^

Q: What should I discuss with my healthcare expert before taking Milnacipran?

  • Inform the doctor about your detailed medical & surgical history
  • Inform your physician if you have any of the following conditions -
  • Liver disease
  • Kidney disease
  • Heart disease, high BP
  • Blood cell disorder e.g. sickle cell or haemophilia
  • Glaucoma
  • Low sodium levels in the body
  • Problems in urination
  • If you drink alcohol
  • If you are taking blood thinners, e.g. warfarin
  • If you are pregnant, lactating or planning a pregnancy

Q: How is this medicine removed from the body?

A: About 58% of medicine is removed through urine.

Q: How long this medicine stays in the body after taking it?

A: Half-life of this medicine is around 8-10 hours; hence, it can stay up to 16-20 hours in the body.
Last Updated on: 05 Oct 2020 | 10:47 PM (IST)

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Disclaimer
The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here  for detailed T&C.
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