Lacosamide
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Molecule Summary
| Uses | Epilepsy |
| Therapy | Anti-Epileptic |
| Side Effects | Headache, dizziness, nausea, vomiting |
Medicines
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Molecule Description
Lacosamide is an anti-epileptic medicine. It is used to manage epilepsy or seizures. Epilepsy is a brain disorder that causes a temporary fault in the brain's electrical activity. This causes people to have seizures and convulsions. It works by stabilizing the electrical activity of nerve cells in the brain, which decreases the frequency of seizures. Take this medicine in the exact dose and duration as prescribed by your doctor. Do not take more than the recommended dose. Do not stop taking this medicine on your own. Before starting Lacosamide, inform the doctor if you are pregnant, planning a pregnancy or breastfeeding and about your detailed medical history.
Uses
Lacosamide is used for the management of epilepsy or seizures.
Contraindications
When should one not use Lacosamide
- If you are allergic to lacosamide or any ingredient of Lacosamide.
- If you have a specific type of heartbeat problem.
Side effects
Common side effects of this drug are:
- Headache
- Dizziness
- Nausea
- Double vision
- Vomiting
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
Talk to your doctor if
- You are getting a feeling of killing or harming yourself after taking this medicine
- You have heart problems like heart failure or irregular heartbeat.
- You feel dizzy and pass out often. This could increase the chances of injury. You should be very careful until you get used to this medicine.
Mode of Action
How Does It Work?
- Lacosamide works by inactivating the voltage-gated sodium channels and stabilizing the electrical activity of nerve cells in the brain. Therefore, it helps in controlling fits or seizures.
Interactions
Interactions with other medicines
- Some medicines can affect the way Lacosamide works or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
- Tell your doctor about all the medicines, supplements or herbals you are currently taking or might take to avoid any possible interaction.
- A few medicines which can increase heart activity, such as medicines for epilepsy or pain called carbamazepine, lamotrigine or pregabalin, should be used with caution along with Lacosamide.
- Caution is recommended when this medicine is used along with antifungal and antibiotic medicines like fluconazole, itraconazole, ketoconazole, clarithromycin, rifampicin, anti-HIV medicine like ritonavir and St John's wort, a herbal medicine used to stabilize mood.
Dosage
Overdose
Symptoms of overdose of Lacosamide include dizziness, vomiting, nausea and convulsions. If you think you have taken too much of this medicine, contact your doctor immediately or visit the nearest hospital.
Missed a Dose
- If you missed any dose of Lacosamide, then take it as soon as you remember.
- If it's time for your next dose, then skip the missed dose and continue with your regular dose schedule.
- Do not take a double dose of medicine to compensate for the missed one.
Frequently Asked Questions (FAQs)
Articles
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References:
- VIMPAT® (lacosamide) [Internet]. Accessdata.fda.gov. 2022 [cited 7 June 2026]
- He Z, Li J. The therapeutic effects of lacosamide on epilepsy-associated comorbidities. Front Neurol. 2023 Mar 16;14:1063703.[cited 7 Jun 2026]
- Doty P, Rudd GD, Stoehr T, Thomas D. Lacosamide. Neurotherapeutics. 2007 Jan;4(1):145-8.[cited 7 Jun 2026]
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