Isosorbide Mononitrate

When should one not use Isosorbide Mononitrate

• Do not take if you are allergic to Isosorbide Mononitrate or any ingredient of this medicine
• Do not take if you are under medication of:
• Viagra (Sildenafil) used for male erectile dysfunction
• Do not take if you have decreased blood supply to the brain

Common side effects of this drug are:

• Severe headache initially but reduces as one continues the medicine
• Flushing
• Unsteadiness
• Nausea and Vomiting
• Pounding and rapid heartbeat
• Drop in blood pressure
• Elevation in level of Methemoglobin in blood, which has less affinity to oxygen, causing reduced oxygenation of tissues (Methemoglobinemia) - a rare, severe side effect

Other General Warnings

• You have recently had a heart attack
• You have an underactive thyroid gland
• You have a head injury or bleeding of the brain
• You have a poor diet or poor circulation
• You have a very low body temperature

How Does It Work?

• Angina is caused by constriction of the vessels supplying muscles of heart causing poor blood flow resulting in chest pain
• This medicine dilates the blood vessels which eases the blood flow in them and decreases the load on heart
• It also facilitates an increased amount of blood to flow to areas which need it

Interactions with other medicines

• Medicines used to treat high blood pressure
• Medicines used to treat heart failure
• Medicines used in the treatment of erectile dysfunction like Sildenafil
• Any medication which may cause a lowering of your blood pressure
• Medicines such as Histamine, which is used to treat allergic reactions
• Medicines used to treat migraines like Ergotamine

Interactions with food items

Overdose

Missed a Dose