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Hyoscyamine

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Molecule Summary

Uses
Stomach and intestinal related conditions
Therapy
Anti-Spasmodics
Side Effects
Dry mouth, nausea, constipation, urine retention, blurred vision
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Molecule Description

Hyoscyamine is an anti-secretory medicine that mainly acts by decreasing the secretion of body fluids and their movement. Hyoscyamine is used to treat various conditions of the stomach and intestine. It should not be used if you have an obstructive condition, hence inform your doctor about all the medical conditions you have or had. Take this medicine as prescribed by your doctor to gain optimal benefits. Some forms of Hyoscyamine are meant to be kept under your tongue until they dissolve; use it exactly as directed by your doctor. Before taking Hyoscyamine, discuss all the medication, supplements and disease conditions with your doctor.

Uses

  • Hyoscyamine is used to treat various stomach and intestinal problems such as cramps, peptic ulcers, irritable bowel syndrome.
  • It is also used to treat other conditions such as bladder and bowel control problems, pain due to cramps caused by kidney stones and gallstones, control gastric secretions, diverticulitis, colic, cystitis and pancreatitis.

Contraindications

When should one not use Hyoscyamine

  • If you are allergic to hyoscyamine or any other component of this medicine.
  • If you have or had glaucoma.
  • If you have an obstructive condition such as bladder neck obstruction due to prostatic hypertrophy.
  • If you have an obstruction of the stomach and intestine.
  • If you have inflammation of the large intestine (colon).
  • If you have unstable heart status including internal bleeding.
  • If you have myasthenia gravis.

Side effects

Common side effects of this drug are:

  • Dry mouth
  • Nausea
  • Constipation
  • Urine retention
  • Blurred vision
  • Increased heart rate
  • Mydriasis (dilated pupil)
  • Loss of taste
  • Headache
  • Drowsiness
  • Dizziness

Precautions and Warnings

Pregnancy

Pregnancy

The use of Hyoscyamine is not recommended during pregnancy as it may cause harm to the unborn baby unless prescribed by the doctor after considering it to be safe and necessary during the pregnancy.

Breast Feeding

Breast Feeding

Hyoscyamine passes into breast milk and it may cause harm to the newborn baby. Hence, you should not consume this medicine if you are breastfeeding, unless considered safe and necessary by your doctor.

Driving

Driving

No, you should not drive after taking Hyoscyamine as it may cause dizziness, sleepiness, drowsiness or blurred vision, which alters the ability to drive.

Alcohol

Alcohol

Do not drink alcohol with Hyoscyamine as it may cause excessive drowsiness.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You are allergic to this or any other medicine.
  • You have kidney, liver or heart disease.
  • You have a neuronal disorder.
  • You have hyperthyroidism (overactive thyroid).
  • You have any other medical condition and on any other medicine.
  • You experience a severe side effect.
  • Hyoscyamine should be used with caution in elderly people.

Mode of Action

How Does It Work?

Hyoscyamine works by decreasing the acid production in the stomach and also decreases secretion of certain body fluids by altering their motility.

Interactions

Interactions with other medicines

  • Concomitant use of Hyoscyamine with dicyclomine, atropine (other antimuscarinics), amantadine, haloperidol (antiparkinson medicine), phenothiazines (anti-fit), isocarboxazid, selegiline (monoamine oxidase (MAO) inhibitors), amitriptyline, nortriptyline (mood elevator) or cetirizine, fexofenadine (anti-allergic medicine) may increase the risk of side effect.
  • Antacids such as aluminium hydroxide alter the effect of Hyoscyamine.
  • Discuss with your doctor about any other medicine, herbal preparation and supplements you are taking currently to avoid any possible drug interactions.

Dosage

Overdose

  • Excess Hyoscyamine may cause headache, nausea, vomiting, blurred vision, dilated pupils, hot dry skin, dizziness, dryness of the mouth, difficulty in swallowing and CNS stimulation (increased alertness, attention, energy and physical activity).
  • If you have taken too much of this medicine then contact your doctor or reach out to the nearest hospital immediately.

Missed a Dose

If you have missed taking any dose of Hyoscyamine then take it as soon as you remember. If it's already time for the next dose then skip the missed dose and follow the regular dosing schedule.

Frequently Asked Questions (FAQs)

No, Hyoscyamine is not a habit-forming medicine.

Hyoscyamine is not a pain killer, it relieves abdominal pain by reducing the muscle contractions.

No, weight gain is not a known side effect of Hyoscyamine.

No, Hyoscyamine is not being used to treat urinary tract infections.

Yes, constipation is the common side effect of Hyoscyamine. It is because it reduces the motility of the intestine and decreases secretion.

Some forms of Hyoscyamine are meant to be kept under your tongue and left to dissolve in your mouth. Use it exactly as directed by your doctor.

Hyoscyamine is itself the active medicine. It is an anti-secretory medicine.

Dry mouth is one of the common side effects that an individual might experience after taking this medicine. But that usually resolves with time. It is advised to frequently rinse your mouth with water or keep having water.

Hyoscyamine starts showing its effect within 1-2 hours of taking it. However, it can vary among patients based on different biological parameters including physiology.

Hyoscyamine is used to treat various stomach and intestinal problems such as cramps, peptic ulcers, irritable bowel syndrome. It is also used to treat other conditions such as bladder and bowel control problems, pain due to cramps caused by kidney stones and gallstones, control gastric secretions, diverticulitis, colic, cystitis and pancreatitis.

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