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Gemfibrozil

Molecule Description

Gemfibrozil is used to treat high cholesterol and triglyceride levels in the blood. High levels of cholesterol may result in blockage of arteries (atherosclerosis), which leads to heart diseases.

Uses of Gemfibrozil

  • To treat high cholesterol levels and triglyceride levels
  • To reduce the risk of stroke, heart attack and other heart problems

Contraindications of Gemfibrozil

When should one not use Gemfibrozil

  • Allergic to Gemfibrozil or any of the other ingredients of it
  • You have liver, kidney or gall bladder disease
  • You have a history of gall stones, photoallergy
  • You are currently taking any medicine called Repaglinide

Side effects of Gemfibrozil

Common side effects of this drug are:

  • Indigestion
  • Spinning (vertigo)
  • Headache, stomach pain
  • Diarrhoea, constipation

Precautions and Warnings of Gemfibrozil

Pregnancy

Q:
Can I take Gemfibrozil during pregnancy?
A:
The effect of Gemfibrozil on the fetus is not known, consult your doctor if you are pregnant, your doctor will tell you on the use of this medicine after assessing the benefits over risks.

Breast Feeding

Q:
Can I take Gemfibrozil while breastfeeding?
A:
It is not safe to use this medicine during breastfeeding.

Driving

Q:
Can I drive if I have consumed Gemfibrozil?
A:
This medicine may sometimes cause dizziness or tiredness. You may drive if you feel comfortable.

Alcohol

Q:
Can I consume alcohol with Gemfibrozil?
A:
Alcohol may interfere with treatment. It is better to avoid drinking alcohol while taking this medicine.

Other General Warnings

Talk to your doctor if
  • You have a history of muscle breakdown (rhabdomyolysis)
  • Kidney impairment
  • Gall bladder diseases
  • Liver disorders
  • Excessive use of alcohol
  • Diabetes

Mode of Action of Gemfibrozil

How Does It Work?

Gemfibrozil reduces cholesterol levels by increasing the activity of an enzyme, which breaks down triglycerides.

Interactions of Gemfibrozil

Interactions with other medicines

  • Colchicine (medicine for gout)
  • Dasabuvir (treatment of Hepatitis C)
  • Paclitaxel (treatment for cancer)
  • Montelukast (treatment for asthma)
  • Repaglinide, Pioglitazone (Anti-diabetic medication)
  • Cholesterol-lowering drugs- ‘statins’
  • Warfarin (blood thinner)
  • Loperamide (treatment of diarrhea)
  • Enzalutamide (medicine for prostate cancer)
  • Selexipag (medicine for the treatment of pulmonary hypertension)

Interactions with food items

No interactions with food have been observed yet.

Dietary Restrictions of Gemfibrozil

Stick to a low-fat diet. Avoid oily food.

Dosage of Gemfibrozil

Overdose

Abdominal cramps, diarrhea, nausea, vomiting, joint, and muscle pain are some of the effects of overdose. Call your doctor immediately in case you suspect an overdose.

Missed a Dose

Take the missed dose as early as you remember. Skip the missed dose if it’s already the time for next scheduled dose. Do not take extra medicine to compensate for the missed dose.

Content Details

WRITTEN BY
REVIEWED BY
doctor

Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)

^

Q: What should I discuss with my healthcare expert before taking Gemfibrozil?

A: You must inform your doctor if you are suffering from any kidney, liver diseases or gall stones or if you are taking blood thinners (like Warfarin) if you are already taking any statin cholesterol medicine.

Q: What else should I keep in mind while I take Gemfibrozil?

A: Follow a healthy diet involving less fat and cholesterol, weight control program, and exercise along with Gemfibrozil for optimum benefits.
Last Updated on: 05 Oct 2020 | 10:47 PM (IST)

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Disclaimer
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts. Please click here for detailed T&C.
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