Fexofenadine
Description
Fexofenadine is a second-generation antihistamine used to treat various allergi
es. It acts as a highly selective antagonist of the H1 histamine receptor. This means it blocks histamine, a key chemical released by the body during an allergic reaction, from binding to its receptors. By inhibiting this process, Fexofenadine prevents histamine from causing common allergic symptoms such as sneezing, nasal congestion, a runny nose, itchy or watery eyes, and skin reactions like hives (urticaria), redness, and swelling. It is non-sedating in nature. Unlike older antihistamines, it does not easily cross the blood-brain barrier (BBB). This ensures that it relieves allergy symptoms without causing significant drowsiness, making it suitable for daytime use and helping maintain alertness. Fexofenadine is commonly prescribed to treat symptoms of Seasonal Allergic Rhinitis (hay fever), Perennial Allergic Rhinitis, and Chronic Idiopathic Urticaria (long-lasting hives). It is available in oral forms, including film-coated tablets and oral suspensions.
Uses
Fexofenadine is used to treat allergic rhinitis, symptoms include watery eyes, runny or blocked nose, itching and sneezing. It is also used to relieve symptoms of skin allergy (urticaria or hives).
Contraindications
When should one not use Fexofenadine
If you are allergic to fexofenadine.
Side effects
Common side effects of this drug are:
- Nausea
- Headache
- Drowsiness
- Dizziness
Precautions and Warnings
Pregnancy
Q:
Can I take Fexofenadine during pregnancy?
A:
There is limited information available about the safety of this medicine in pregnancy. This medicine should be used during pregnancy only if prescribed by your doctor. Inform your doctor if you are pregnant, think you might be pregnant or are planning a pregnancy.
Breast Feeding
Q:
Can I take Fexofenadine while breastfeeding?
A:
Fexofenadine passes into the breastmilk. Thus, it is recommended not to take this medicine while breastfeeding, unless advised by your doctor.
Driving
Q:
Can I drive if I have consumed Fexofenadine?
A:
Fexofenadine does not affect the ability to drive or operate machinery. However, caution is advised while driving or doing anything that requires concentration, as it may cause dizziness and sleepiness in some.
Alcohol
Q:
Can I consume alcohol with Fexofenadine?
A:
No, you should avoid drinking alcohol while on this medicine as it may make you feel sleepy and increase side effects.
Other General Warnings
Talk to your doctor if
- You are suffering from liver or kidney disease.
- You are suffering from any heart disease as this medicine is known to increase your heartbeat.
- You are an elderly person.
- Fexofenadine should not be used by children below the age of 12 unless prescribed by their doctor.
Mode of Action
How Does It Work?
Fexofenadine blocks the release of natural substance histamine responsible for various allergic conditions. Thus, helps relieve symptoms of allergic conditions.
Interactions
Interactions with other medicines
- Some medicines can affect the way Fexofenadine works or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
- Tell your doctor about all the medicines, supplements or herbals you are currently taking or might take to avoid any possible interaction.
- Especially, if you are taking medicines such as ketoconazole and erythromycin to treat infections.
- Acidity medicines should be taken two hours before this medicine and not along with it.
Interactions with food items
- You should avoid grapefruit juice, apple juice or orange juice while on this medicine, as it may increase the side effects of this medicine.
Dosage
Overdose
Symptoms of an overdose can lead to dizziness, drowsiness, fatigue and dry mouth. If you think you have taken too much of this medicine contact your doctor immediately or visit the nearest hospital.
Missed a Dose
If you have missed any dose of this medicine, take it as soon as you remember. If it's time for your next dose, then skip the missed dose and continue with your regular dosing schedule. Do not take a double dose of medicine to compensate for the missed one....
Content Details
WRITTEN BY
Nancy Dixit
B. Pharm, M. Pharm
REVIEWED BY
Dr. Ritu Budania
MBBS, MD (Pharmacology)
Frequently Asked Questions (FAQs)
Q: Will Fexofenadine make me feel sleepy?
A: Fexofenadine is a non-sedating antihistamine, meaning it is much less likely to make you feel sleepy than older types (first-generation antihistamines). However, while the risk is low, some people still report feeling sleepy or dizzy after taking it. It is always wise to see how your body reacts to the medication before driving, operating heavy machinery, or performing any task that requires full concentration. Also, avoid drinking alcohol, as it can increase the risk of feeling drowsy.
Q: Who should avoid taking Fexofenadine?
A: Patients who are allergic to any component of Fexofenadine should avoid taking this medicine or if you have experienced allergy after taking similar medicines.
Q: Can I take Fexofenadine with my vitamin supplements?
A: Fexofenadine may interact with certain medicines or supplements taken at the same time. That can also lead to the altered desired action. Before initiating treatment with Fexofenadine, inform your doctor about all the medicines, supplements, or herbal products you are taking.
Q: What should you not take with Fexofenadine?
A: You should not drink grapefruit juice, apple juice or orange juice while you're taking Fexofenadine. It might make you more likely to get side effects.
Q: How long can Fexofenadine be taken?
A: It is advised to talk to your doctor if you're unsure how long you should take Fexofenadine. You should not to take it for longer than the prescribed duration without consulting a doctor.
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Disclaimer
The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here for detailed T&C.
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