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Fexofenadine

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Molecule Summary

Uses
Allergic Rhinitis, Urticaria
Therapy
Anti-Allergic
Side Effects
Dizziness, Drowsiness, Headache, Nausea
3 Step Quality
Assurance
Cash on delivery
available
NPPA
Regulated

Molecule Description

Fexofenadine is a second-generation antihistamine used to treat various allergies. It acts as a highly selective antagonist of the H1 histamine receptor. This means it blocks histamine, a key chemical released by the body during an allergic reaction, from binding to its receptors. By inhibiting this process, Fexofenadine prevents histamine from causing common allergic symptoms such as sneezing, nasal congestion, a runny nose, itchy or watery eyes, and skin reactions like hives (urticaria), redness, and swelling. It is non-sedating in nature. Unlike older antihistamines, it does not easily cross the blood-brain barrier (BBB). This ensures that it relieves allergy symptoms without causing significant drowsiness, making it suitable for daytime use and helping maintain alertness. Fexofenadine is commonly prescribed to treat symptoms of Seasonal Allergic Rhinitis (hay fever), Perennial Allergic Rhinitis, and Chronic Idiopathic Urticaria (long-lasting hives). It is available in oral forms, including film-coated tablets and oral suspensions.

Uses

Fexofenadine is used to treat allergic rhinitis, symptoms include watery eyes, runny or blocked nose, itching and sneezing. It is also used to relieve symptoms of skin allergy (urticaria or hives).

Contraindications

When should one not use Fexofenadine

If you are allergic to fexofenadine.

Side effects

Common side effects of this drug are:

  • Nausea
  • Headache
  • Drowsiness
  • Dizziness

Precautions and Warnings

Pregnancy

Pregnancy

There is limited information available about the safety of this medicine in pregnancy. This medicine should be used during pregnancy only if prescribed by your doctor. Inform your doctor if you are pregnant, think you might be pregnant or are planning a pregnancy.

Breast Feeding

Breast Feeding

Fexofenadine passes into the breastmilk. Thus, it is recommended not to take this medicine while breastfeeding, unless advised by your doctor.

Driving

Driving

Fexofenadine does not affect the ability to drive or operate machinery. However, caution is advised while driving or doing anything that requires concentration, as it may cause dizziness and sleepiness in some.

Alcohol

Alcohol

No, you should avoid drinking alcohol while on this medicine as it may make you feel sleepy and increase side effects.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You are suffering from liver or kidney disease.
  • You are suffering from any heart disease as this medicine is known to increase your heartbeat.
  • You are an elderly person.
  • Fexofenadine should not be used by children below the age of 12 unless prescribed by their doctor.

Mode of Action

How Does It Work?

Fexofenadine blocks the release of natural substance histamine responsible for various allergic conditions. Thus, helps relieve symptoms of allergic conditions.

Interactions

Interactions with other medicines

  • Some medicines can affect the way Fexofenadine works or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
  • Tell your doctor about all the medicines, supplements or herbals you are currently taking or might take to avoid any possible interaction.
  • Especially, if you are taking medicines such as ketoconazole and erythromycin to treat infections.
  • Acidity medicines should be taken two hours before this medicine and not along with it.

Interactions with food items

  • You should avoid grapefruit juice, apple juice or orange juice while on this medicine, as it may increase the side effects of this medicine.

Dosage

Overdose

Symptoms of an overdose can lead to dizziness, drowsiness, fatigue and dry mouth. If you think you have taken too much of this medicine contact your doctor immediately or visit the nearest hospital.

Missed a Dose

If you have missed any dose of this medicine, take it as soon as you remember. If it's time for your next dose, then skip the missed dose and continue with your regular dosing schedule. Do not take a double dose of medicine to compensate for the missed one.

Frequently Asked Questions (FAQs)

Fexofenadine is a non-sedating antihistamine, meaning it is much less likely to make you feel sleepy than older types (first-generation antihistamines). However, while the risk is low, some people still report feeling sleepy or dizzy after taking it. It is always wise to see how your body reacts to the medication before driving, operating heavy machinery, or performing any task that requires full concentration. Also, avoid drinking alcohol, as it can increase the risk of feeling drowsy.

Patients who are allergic to any component of Fexofenadine should avoid taking this medicine or if you have experienced allergy after taking similar medicines.

Fexofenadine may interact with certain medicines or supplements taken at the same time. That can also lead to the altered desired action. Before initiating treatment with Fexofenadine, inform your doctor about all the medicines, supplements, or herbal products you are taking.

You should not drink grapefruit juice, apple juice or orange juice while you're taking Fexofenadine. It might make you more likely to get side effects.

It is advised to talk to your doctor if you're unsure how long you should take Fexofenadine. You should not to take it for longer than the prescribed duration without consulting a doctor.

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