Eltrombopag

• Severe Aplastic Anemia
• Chronic Immune Thrombocytopenia
• Chronic Hepatitis C-associated Thrombocytopenia
• Thrombocytopenic Purpura (ITP)

When should one not use Eltrombopag

• If you are allergic to this medicine
• If you have liver problems
• If you have cataracts (the lens of the eye-getting cloudy)
• If you have another blood condition such as Myelodysplastic Syndrome (MDS)

Common side effects of this drug are:

• Common side effects:
• Common cold
• Nausea
• Diarrhea
• Abdominal pain
• Cough
• Infection in the nose, sinuses, throat and upper airways, common cold (upper respiratory tract infection)
• Muscle pain, muscle spasm, muscle weakness
• Back pain, bone pain
• Heavy menstrual period
• Sore throat and discomfort when swallowing
• Eye problems like dry eye, eye pain, and blurred vision
• Vomiting
• Flu (influenza)
• Pneumonia
• Hair loss
• Loss of appetite
• Swelling in the hands or feet
• Serious side effects
• High risk of blood clots
• Liver problems- yellowing of the skin or eyes (jaundice), unusually dark-coloured urine, increased of liver enzymes
• Bleeding or bruising after stopping treatment
• Disturbances of heart rhythm (QT prolongation)

Other General Warnings

• Inform doctor:
• If you feel swelling, pain or tenderness in one leg
• If you experience sudden shortness of breath especially together with sharp pain in the chest or rapid breathing
• If you feel abdominal (stomach) pain, enlarged abdomen, blood in your stools

How Does It Work?

Interactions with other medicines

• Antacid medicines to treat indigestion, heartburn or stomach ulcers
• Medicines called Statins - to lower cholesterol
• Medicines to treat HIV infection, such as Lopinavir and Ritonavir
• Ciclosporin used in the context of transplantations or immune diseases
• Minerals such as iron, calcium, magnesium, aluminium, zinc which may be found in vitamin and mineral supplements
• Medicines such as Methotrexate and Topotecan, to treat cancer

Interactions with food items

Overdose

• If you overdose on the medicine, you may see symptoms such as severe disorders of blood cells and harmful effects of the bone marrow. Contact your doctor immediately.

Missed a Dose