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Elagolix

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Molecule Summary

Uses
Endometriosis
Therapy
Analgesic For Severe Pain
Side Effects
Night sweats, headaches, nausea, trouble sleeping, missed periods, anxiety, joint pain, depression, and mood fluctuations.
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Molecule Description

Elagolix is a medicine used to treat moderate to severe pain associated with endometriosis. It works by lowering the hormone levels that cause tissue to grow in the uterus, which helps reduce pain and discomfort. Take the medicine exactly as prescribed by your doctor. Take it at the same time every day. It can be taken with or without food. This medicine is not meant for use in children. Do not take Elagolix if you are pregnant, have osteoporosis, or have severe liver disease. Common side effects of this medicine are night sweats, headaches, nausea, trouble sleeping, missed periods, anxiety, joint pain, depression, and mood swings.

Uses

Elagolix is used for the management of moderate to severe pain associated with endometriosis.

Contraindications

When should one not use Elagolix

  • If you are or may be pregnant.
  • If you have osteoporosis.
  • If you have severe liver disease.
  • If you are taking medicines such as cyclosporine, gemfibrozil, some statins, antibiotics, and antiretroviral drugs. Ask your doctor if you are not sure if you are taking one of these medicines.

Side effects

Common side effects of this drug are:

  • Night sweats
  • Headaches
  • Nausea
  • Trouble sleeping
  • Missed periods
  • Anxiety
  • Joint pain
  • Depression
  • Mood fluctuations

Precautions and Warnings

Pregnancy

Pregnancy

Do not take Elagolix if you are trying to conceive or are already pregnant, as it may heighten the risk of early pregnancy loss. If you suspect that you are pregnant, discontinue use immediately and contact your healthcare provider.

Breast Feeding

Breast Feeding

Consult your doctor if you are using Elagolix while breastfeeding.

Driving

Driving

It remains unclear if Elagolix influences driving capabilities. Avoid driving if you notice any symptoms impacting your concentration or reaction times.

Alcohol

Alcohol

It is not known whether it is safe to consume alcohol with Elagolix. Please consult your doctor.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You have or have had broken bones.
  • You have other conditions or take medicines that may cause bone problems.
  • You have or have had depression, mood problems or suicidal thoughts or behavior.
  • You have liver problems.
  • You think you may be pregnant. You should avoid becoming pregnant while taking this medicine.
  • You are breastfeeding or plan to breastfeed. It is not known if this medicine passes into breast milk. Talk to your healthcare provider about the best way to feed your baby if you take Elagolix.
  • Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Mode of Action

How Does It Work?

Elagolix works by decreasing the amount of certain hormones in the body that cause endometriosis. It stops the signals that trigger the production of luteinising hormone (LH) and follicle-stimulating hormone (FSH). This leads to lower levels of oestrogen and progesterone, which can ease symptoms such as menstrual cramps and pelvic pain.

Interactions

Interactions with other medicines

  • It is advised to monitor clinical levels of digoxin when used alongside Elagolix.
  • The combined use of Elagolix and rifampin is discouraged.
  • If midazolam is being taken with this medicine, your doctor may adjust the dosage according to the patient's response.
  • Notify your doctor if you are taking rosuvastatin.

Dosage

Overdose

If you have taken too much of this medicine, then contact your doctor or reach out to the nearest hospital immediately, as an overdose may result in side effects.

Missed a Dose

If you have missed taking any dose of this medicine, then take it as soon as you remember. If it's already time for the next dose, then skip the missed dose and follow your regular dosing schedule.

Frequently Asked Questions (FAQs)

No, you should never abruptly discontinue Elagolix without your doctor's guidance. Stopping it suddenly might lead to a rapid return of symptoms. Always adhere to your doctor's recommendations regarding the treatment duration.

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