Dolutegravir

When should one not use Dolutegravir

• If you (or your child) are allergic to dolutegravir or any other ingredient in the medicine.
• If you (or your child) are currently using another medication called fampridine (also known as dalfampridine), which is used to treat multiple sclerosis.

Common side effects of this drug are:

• Headache
• Diarrhoea
• Nausea
• Vomiting
• Rash
• Itching

Other General Warnings

• You have a history of depression or other mental health issues, as some side effects, such as suicidal thoughts or attempts, are more common in these individuals.
• You are a child under 6 years of age, weighing less than 14 kg, or with HIV that is resistant to similar medicines.
• You are taking antacids (for indigestion and heartburn), they can stop Dolutegravir from being properly absorbed by your body, making it less effective.

How Does It Work?

Interactions with other medicines

• Dolutegravir can interact with other medicines. Always inform your doctor if you (or your child) are taking, have recently taken, or plan to take any other medicines, including herbal remedies.
• Avoid taking this medicine with fampridine (dalfampridine), which is used for multiple sclerosis.
• Your doctor may need to monitor you more closely if you are taking metformin to treat diabetes.
• Antacids are for indigestion and heartburn.
• Supplements or multivitamins that contain calcium, iron, or magnesium.
• Etravirine, efavirenz, fosamprenavir/ritonavir, nevirapine, or tipranavir/ritonavir are used to treat HIV infection.
• Rifampicin is used to treat tuberculosis (TB) and other bacterial infections.
• Phenytoin and phenobarbital are used to treat epilepsy.
• Oxcarbazepine and carbamazepine are used to treat epilepsy or bipolar disorder.
• St. John's wort (Hypericum perforatum) is a herbal remedy for depression.

Overdose

Missed a Dose