Daratumumab
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Molecule Summary
| Uses | Multiple myeloma |
| Therapy | Anti-Neoplastic |
| Side Effects | Chills, sore throat, cough, feeling nauseous, vomiting, itchy, runny, or blocked nose, shortness of breath, infusion-related reactions, and reduced blood cell counts. |
Medicines
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19k pincodes
Molecule Description
Daratumumab is used in the treatment of multiple myeloma, which is a type of cancer that affects plasma cells. It is an anticancer medication that targets abnormal cell growth. Daratumumab can be administered alone or in combination with other cancer treatments.
Infusion reactions, such as a swollen face, lips, mouth, tongue, or throat, along with difficulty swallowing or breathing, are common side effects of this medication. Daratumumab may decrease the number of blood cells, particularly white blood cells, increasing the risk of infections. Therefore, regular blood tests are necessary to monitor blood cell levels while you are taking this medication. Daratumumab is not recommended for individuals under the age of 18.
It's important to inform your healthcare team about all medications you are currently using, as many other medicines can interact with this one. This medicine is not recommended for use during pregnancy or while breastfeeding. To prevent pregnancy, it is essential for both males and females to use effective contraception throughout the treatment.
Uses
Daratumumab is a prescription medicine used to treat adults diagnosed with multiple myeloma, a form of cancer that affects plasma cells in the bone marrow.
Contraindications
When should one not use Daratumumab
If you are allergic to daratumumab or any of the other ingredients in this medicine.
Side effects
Common side effects of this drug are:
- Chills
- Sore throat
- Cough
- Feeling sick (nausea)
- Vomiting
- Itchy, runny, or blocked nose
- Feeling short of breath or other breathing problems
- Infusion-related reactions
- Reduced number of blood cells (including white blood cells), which can increase the risk of infections
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
Talk to your doctor if
- You have a history of breathing problems.
- You have had shingles (herpes zoster).
- You have ever had or might now have a hepatitis B infection.
- You get worsening tiredness or yellowing of your skin or white part of your eyes.
- You have hereditary fructose intolerance (HFI).
- You are pregnant or plan to become pregnant.
- You are breastfeeding or plan to breastfeed.
- You have kidney disease or have had a kidney transplant or liver disease.
Mode of Action
How Does It Work?
Daratumumab is a targeted cancer medicine known as a monoclonal antibody. Monoclonal antibodies specifically target proteins located on the surface of cancer cells. It targets a protein called CD38 found on myeloma cells, enabling your immune system to recognize these cells. This recognition allows the immune system to attack and destroy the myeloma cells effectively.
Dosage
Overdose
Your doctor or nurse will give Daratumumab. Therefore, the chances of overdose are very rare. If you experience the symptoms right after receiving the medicine, seek medical help.
Missed a Dose
Your doctor or nurse will carefully monitor and schedule your medicine, making it unlikely for a dose to be missed. However, if you suspect a dose might have been overlooked, let them know immediately.
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