Dapagliflozin
Description
Dapagliflozin is an anti-diabetic medication used for the treatment of type 2 d
iabetes, alongside diet and exercise. Its mechanism of action involves helping the kidneys excrete excess blood sugar (glucose) through the urine, thereby lowering high blood sugar levels. The medication's effectiveness is optimized when combined with a healthy diet and regular exercise. Before starting treatment, patients must inform their healthcare provider about their complete medical history, previous health conditions, and any other medications, including their pregnancy and breastfeeding status. Uncontrolled diabetes poses a high risk of serious health complications, including problems with the eyes, kidneys, and nerves, as well as heart diseases and stroke. Potential side effects include low blood sugar (Hypoglycemia), genital infections, increased frequency of urination, painful urination, back pain, dizziness, and rash.
Uses
This medicine is prescribed along with diet and exercise program to control high blood sugar in people with Type 2 diabetes.
Contraindications
When should one not use Dapagliflozin
If you are allergic to this medicine.
Side effects
Common side effects of this drug are:
- Infection (thrush) of your penis or vagina (like irritation, itching, unusual discharge or odour)
- Back pain and frequent urination
- Changes in the amount of cholesterol or red blood cells in your blood
- Dizziness
- Rash
Precautions and Warnings
Pregnancy
Q:
Can I take Dapagliflozin during pregnancy?
A:
It is not safe in pregnancy as it may cause to harm to unborn baby. Inform your doctor if you are pregnant while taking this medicine. Seek for more reliable alternative medicine to control your sugar.
Breast Feeding
Q:
Can I take Dapagliflozin while breastfeeding?
A:
It is not recommended during breastfeeding, as it is not known if Dapagliflozin passes into human breast milk. Talk to your doctor before continuing this treatment if you are breastfeeding.
Driving
Q:
Can I drive if I have consumed Dapagliflozin?
A:
If you are taking Dapagliflozin along with other antidiabetic medicines, there are chances of low blood sugar levels. You may experience faintness, confusion, and increased sweating. These are the signs of low blood glucose levels. Keep juice or chocolate handy while driving. In case you start experiencing any of these symptoms, immediately have it.
Alcohol
Q:
Can I consume alcohol with Dapagliflozin?
A:
Alcohol may cause a fall in blood glucose levels in patients with diabetes. Avoid alcohol consumption on this treatment.
Other General Warnings
Talk to your doctor if
- You feel sick, stomach pain, excessive thirst, fast and deep breathing, confusion, tiredness
- You have diabetic ketoacidosis (increased levels of 'ketone bodies' in your urine or blood) seen in tests
- You are suffering from kidney or liver problems
- You have high blood pressure or very high levels of sugar in your blood
- You feel nausea, vomiting or fever
- You have any severe urinary infection
- You have no production of insulin (Type 1 diabetes)
Mode of Action
How Does It Work?
Dapagliflozin works by helping the kidneys remove excess glucose (sugar) and calories in the urine, which then helps lower the blood sugar level.
Interactions
Interactions with other medicines
It is essential to let your doctor know about all the medicine you are taking. Some medications that may interact with Dapagliflozin, include Acetaminophen, Albuterol, Celecoxib, Cholecalciferol, Exenatide, and Glucose....
Interactions with food items
No information is available on interactions of Dapagliflozin when taken with food, consult your doctor or pharmacist for further information.
Dietary Restrictions
No information is available on dietary restrictions while you are taking Dapagliflozin, consult your doctor or pharmacist for further details.
Dosage
Overdose
Dapagliflozin overdose can make you dehydrated, or you can develop nausea, vomiting, or fever. Low blood sugar levels can be present as varied symptoms, tremors, slurred speech, or fainting. You can often get infections of the urinary tract. Seek emergency medical attention immediately....
Missed a Dose
If you miss any dose of this medicine, take it as soon as possible. If it is the time for your next dose, skip the missed dose, and go back to your regular dose schedule. Do not take two dosages at once....
Content Details
WRITTEN BY
Dr. Mansi Savla
B. Pharm, PharmD
REVIEWED BY
Dr. Ritu Budania
MBBS, MD (Pharmacology)
Frequently Asked Questions (FAQs)
Q: What special precautions should I follow?
A: Check your blood sugar levels as directed by your doctor. Take medicine as directed and consult a doctor if your condition worsens.
Q: What should I discuss with my healthcare expert before starting on this medicine?
A: Give a detailed account of your medical and surgical history. Also, mention to your doctor all the prescription and non-prescription medicines, herbal preparations, and nutritional supplements that you may be taking before you start this medicine. Women should give details of their pregnancy and breastfeeding status.
Q: What are the most common side effects I should watch out for?
A: The most common side effects are genital yeast infections (in both men and women) and urinary tract infections (UTIs), as well as urinating more often. Drinking enough water and practicing good hygiene can help.
Q: How does Dapagliflozin work in my body?
A: It works by helping your kidneys remove excess sugar (glucose) from your blood and pass it out through your urine (pee).
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Disclaimer
The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here for detailed T&C.
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