Colistin

Uses	Serious bacterial infection
Therapy	Antibiotic
Side Effects	Injection site reactions, skin rash, dizziness

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Molecule Description

Colistin is an antibiotic medicine. It is used in the treatment of certain types of severe bacterial infections. It is also called polymyxin E or colistimethate. It will be given to you in a hospital or clinic by a doctor or nurse as an injection. You should avoid self-injecting.

Uses

For the treatment of severe bacterial infections

Contraindications

When should one not use Colistin

If you are allergic to colistin or any other ingredient of this medicine

Side effects

Common side effects of this drug are:

Injection site reaction
Skin rash
Dizziness

Precautions and Warnings

Pregnancy

Colistin should be used during pregnancy only if considered essential by the doctor after assessing the benefits over risks, as limited safety data is available in pregnant women.

Breast Feeding

Colistin should be used while breastfeeding only if considered essential by the doctor

Driving

Colistin may cause dizziness, confusion, visual disturbance. Caution is needed while driving or operating machines.

Alcohol

Although there is no known interaction between alcohol and this medicine, it is essential to consult your physician if you have a habit of consuming alcohol regularly.

Other General Warnings

Talk to your doctor if

You have problems with your kidneys
You have asthma
You are suffering from a condition that causes muscle weakness (myasthenia gravis)
You have porphyria (a rare inherited metabolic disorder)

Mode of Action

How Does It Work?

Colistin is an antibiotic that kills the bacteria by damaging the cell membrane and thus stops the growth of bacteria

Interactions

Interactions with other medicines

Some medicines can affect the way Colistin works, or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
Tell your doctor about all the medicines, supplements, or herbals you are currently taking or might take to avoid any possible interaction.
Especially if you are taking antibiotics, muscle relaxants, medicines to treat a condition called myasthenia gravis (muscle weakness).

Dosage

Overdose

Colistin will be given to you by a doctor or nurse. Therefore, it is less likely that you may get an overdose on this medicine. If you experience any symptoms right after receiving this medicine, seek medical help.

Missed a Dose

The doctor or nurse usually gives Colistin in the hospital or clinic. Therefore, the chances of missing a dose are less. However, if you feel that a dose has been missed, please inform your doctor and nurse.