Clindamycin+Vitamin B3 / Nicotinic Acid / Niacin
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Molecule Summary
| Uses | Acne, pimples, whiteheads and blackheads |
| Therapy | Anti-Acne |
| Side Effects | Burning, redness, oily skin, swelling, skin irritation, hives, itching, dry skin |
Medicines
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19k pincodes
Molecule Description
Clindamycin+Vitamin B3 / Nicotinic Acid / Niacin is a topical medication designed to help manage and treat various skin conditions, including acne, blackheads, and whiteheads.
The medicine's effectiveness comes from its two main active ingredients: clindamycin and nicotinamide. Clindamycin is a potent antibiotic that targets and inhibits the growth of specific bacteria that cause acne. Reducing the bacterial population on your skin helps decrease inflammation and the overall number of pimples. Nicotinamide, a form of vitamin B3, acts as a strong anti-inflammatory agent. It helps to soothe irritated skin and reduce the redness and swelling that often accompany acne, working in harmony with clindamycin to calm and heal your skin.
To achieve the best results with Clindamycin+Vitamin B3 / Nicotinic Acid / Niacin, it is essential to use it exactly as your doctor has prescribed. After gently cleansing and drying the affected area, apply a very thin layer of the medicine. Remember, a little goes a long way, and using more than directed will not speed up the process. Consistency is key, so be sure to apply the medicine regularly as instructed, typically once or twice a day. Patience is also important, as it may take several weeks of consistent use before you begin to see significant improvements in your skin's condition.
Like most medications, Clindamycin+Vitamin B3 / Nicotinic Acid / Niacin may cause some temporary side effects. The most common ones include dryness, itching, and a mild burning or stinging sensation on the treated skin. These effects are usually mild and tend to subside as your skin gets accustomed to the medicine. If you experience severe or persistent side effects, it is essential to consult your doctor for guidance. Always inform your healthcare provider about any pre-existing medical conditions and all medications you are currently taking to ensure Clindamycin+Vitamin B3 / Nicotinic Acid / Niacin is a safe and suitable option for you.
Uses
Clindamycin+Vitamin B3 / Nicotinic Acid / Niacin is effectively used in the treatment of bacterial infection and inflammation of the skin such as acne, pimples, whiteheads and blackheads.
Contraindications
When should one not use Clindamycin+Vitamin B3 / Nicotinic Acid / Niacin
- If you are allergic to clindamycin, nicotinamide (vitamin B3) or any other components of Clindamycin+Vitamin B3 / Nicotinic Acid / Niacin.
- If you have experienced diarrhoea after using an antibiotic.
- If you have a history of inflammatory bowel disease.
Side effects
Common side effects of this drug are:
- Burning
- Redness
- Oily skin
- Swelling
- Skin irritation
- Hives
- Itching
- Dry skin
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
Talk to your doctor if
- You have a history of any allergic skin reaction
- You experience excessive dryness, irritation and peeling of skin
- You have a history of inflammation of the colon or antibiotic-associated diarrhoea
- You are allergic to any components of this medicine
- You should avoid contact with eyes, nose and mouth
Mode of Action
How Does It Work?
- Clindamycin is an antibiotic commonly used to treat various bacterial infections of the skin. It works by inhibiting the growth and multiplication of acne-causing bacteria.
- Nicotinamide, on the other hand, acts as an anti-inflammatory agent. It helps reduce the swelling and redness associated with acne. Additionally, it regulates the production of oil by the skin's oil glands, which can contribute to acne.
Interactions
Interactions with other medicines
- Clindamycin+Vitamin B3 / Nicotinic Acid / Niacin is applied externally on the skin, thus it is less likely to interact with other medicines taken orally. However, it may interact with other topically applied creams and gels. Discuss with your doctor if you are already on another topical gel or cream
- There is limited information available on the interaction of Clindamycin+Vitamin B3 / Nicotinic Acid / Niacin with other medicines. However, as this medicine contains clindamycin & nicotinamide, any interaction seen with these two components when taken alone may occur with this combination
- You need to be cautious if you are taking oral anticoagulants like Warfarin, Acenocoumarol and Fluindione as this medicine may interact with them. Regular monitoring of blood coagulation parameters is recommended
Interactions with food items
Clindamycin+Vitamin B3 / Nicotinic Acid / Niacin is for external use only.
Dosage
Overdose
Clindamycin+Vitamin B3 / Nicotinic Acid / Niacin is meant for external application. The cases of overdose are unlikely. However, upon accidental ingestion reach out to your doctor immediately or visit the nearest hospital. If you have overapplied it, wipe out excess gel with the help of a clean tissue or cotton.
Missed a Dose
Missing an application of Clindamycin+Vitamin B3 / Nicotinic Acid / Niacin may reduce the effectiveness of the treatment. If you have missed applying this medicine, use it as soon as possible. Do not overuse this medicine to compensate for the missed application.
Frequently Asked Questions (FAQs)
Articles
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References:
- Dalacin T Topical Lotion or Clindamycin Phosphate Topical Lotion - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2021 [cited 3 June 2026]
- Dalacin T Topical Lotion or Clindamycin Phosphate Topical Lotion - Patient Information Leaflet (PIL) - (emc) [Internet]. Medicines.org.uk. 2021 [cited 3 June 2026]
- MedlinePlus. Clindamycin. Accessed on: 14 Jan 2025.
- Murphy PB, Bistas KG, Patel P, et al. Clindamycin. [Updated 2024 Feb 28]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-.Accessed on: 14 Jan 2025.
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