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Chlorpheniramine / Chlorphenamine

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Molecule Summary

Uses
Anti-allergic
Therapy
Cough Cold Preparation
Side Effects
Sleepiness, irritation, dryness of nose, mouth or throat, anxiety
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Molecule Description

Chlorpheniramine / Chlorphenamine is an antiallergic medicine used in common cold and allergy including allergy to pollen or dust. It belongs to the antiallergic group of medicines. It works by opposing the action of histamine, formed in the body in certain allergic conditions. Take as prescribed by a doctor. Chlorpheniramine / Chlorphenamine should not be used in pregnancy, breastfeeding, and children below 6-years of age. Inform the doctor about other medicines you are consuming, especially the medicines for brain diseases or to induce sleep, as concomitant use of the medicines with Chlorpheniramine / Chlorphenamine, causes excessive sleepiness.

Uses

Chlorpheniramine / Chlorphenamine is used to relieve symptoms of common cold, allergy, and hay fever, an allergy caused by pollen or dust. The symptoms may include runny nose, sneezing, itching of eyes, nose or throat, red eyes, and watering from eyes.

Contraindications

When should one not use Chlorpheniramine / Chlorphenamine

  • If you have a stomach or duodenal ulcer.
  • If you have glaucoma, a condition where eye pressure is increased.
  • If you may have a urinary bladder or prostate problem.
  • If you are taking medicines for psychiatric disorders (MAO inhibitors).
  • The medicine should not be given to a child less than 6-years of age.

Side effects

Common side effects of this drug are:

  • Sleepiness
  • Irritation
  • Dryness of nose, mouth or throat
  • Anxiety
  • Constipation
  • Fast heartbeat

Precautions and Warnings

Pregnancy

Pregnancy

Components of Chlorpheniramine / Chlorphenamine are known to be harmful to the unborn baby. Thus, it should be avoided in pregnant women. If you become pregnant while on the treatment with the medicine, then immediately inform the doctor.

Breast Feeding

Breast Feeding

There is limited information available on the use of Chlorpheniramine / Chlorphenamine in breastfeeding mothers. However, as a component of the medicine is known to be excreted in milk, the medicine should be avoided if you are breastfeeding.

Driving

Driving

Chlorpheniramine / Chlorphenamine causes sleepiness. If you are taking the medicine, then avoid driving.

Alcohol

Alcohol

Consuming alcohol along with Chlorpheniramine / Chlorphenamine increases sleepiness. Therefore, alcohol drinking should be avoided while taking the medicine.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You may develop an allergic reaction after taking Chlorpheniramine / Chlorphenamine
  • You have liver or kidney diseases.
  • You have asthma or other breathing problems.
  • Your blood pressure is high.
  • You have an overactive thyroid.
  • You have an allergy to other medicines or food.
  • You are taking medicines for sleeplessness.

Mode of Action

How Does It Work?

Chlorpheniramine / Chlorphenamine works by opposing the action of histamine, a chemical formed in the body in certain allergic conditions.

Interactions

Interactions with other medicines

  • Certain medicines can interfere with the action of Chlorpheniramine / Chlorphenamine or Chlorpheniramine / Chlorphenamine itself may affect the action of other medicines taken at the same time.
  • Always inform the doctor about medicines you are taking, that includes prescribed or non-prescribed herbal medicines, dietary supplements as well as other treatment if you are taking for other disorder.
  • If you are on medications like antipsychotic medicine, antiepileptic medicines such as phenytoin, medicines used to induce calmness etc.
  • Other medicines that should be used with caution are moclobemide, Phenelzine, and Tranylcypromine, as they may interfere with the action of Chlorpheniramine / Chlorphenamine when given together.

Dosage

Overdose

  • Symptoms of an overdose of Chlorpheniramine / Chlorphenamine include sleepiness, dry mouth, flushing, fever, confusion, weakness, ringing sensation in ears, blurring of vision, sleeplessness, and rarely seizures.
  • If you have taken too much of the medicine, then contact the doctor or reach out to the nearest hospital immediately.

Missed a Dose

If you have missed a dose of Chlorpheniramine / Chlorphenamine, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and follow the regular dosing schedule.

Frequently Asked Questions (FAQs)

Yes, sleepiness is the main side effect of Chlorpheniramine / Chlorphenamine. It belongs to a group of medicines called sedating antihistamines.

Chlorpheniramine / Chlorphenamine works by opposing the action of a substance called histamine, a chemical formed in the body in certain allergic conditions.

Taking Chlorpheniramine / Chlorphenamine with other cold or allergy medicine should be avoided, as it may increase sleepiness or may cause other untoward side effects.

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