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Chloramphenicol+Dexamethasone+Polymyxin B

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Molecule Summary

Uses
Bacterial eye infection
Therapy
Ocular Antibiotic And Steroid
Side Effects
Burning, itching and dryness of eye
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Molecule Description

Chloramphenicol+Dexamethasone+Polymyxin B is used to treat eye infections mainly caused by bacterial organisms. Chloramphenicol+Dexamethasone+Polymyxin B contains a combination of three medicines, polymyxin B, chloramphenicol and dexamethasone as the active ingredients. Polymyxin B and chloramphenicol are antibiotic medicines, while dexamethasone is a steroid medicine that reduces redness, pain and swelling of the eyes. Chloramphenicol+Dexamethasone+Polymyxin B should be used in a dose and duration prescribed by your doctor. Complete the course given by your doctor. If you find any discomfort after using this medicine or there is no improvement in your condition after using this medicine, then immediately inform your doctor. Chloramphenicol+Dexamethasone+Polymyxin B is meant for external use, and it should be used on the eyes and the area near the eye.

Uses

Chloramphenicol+Dexamethasone+Polymyxin B is used to treat the bacterial infection of the eyes.

Contraindications

When should one not use Chloramphenicol+Dexamethasone+Polymyxin B

  • If you are allergic to polymyxin B, chloramphenicol, dexamethasone or any component of this medicine.
  • If you have varicella, herpes, HIV, tuberculosis or any other viral or fungal infection of the eye.

Side effects

Common side effects of this drug are:

  • Itching
  • Burning sensation
  • Dryness
  • Loss of skin pigmentation
  • Allergic rashes, swelling

Precautions and Warnings

Pregnancy

Pregnancy

There is limited information about the effect of Chloramphenicol+Dexamethasone+Polymyxin B during pregnancy. However, a component of this medicine may cross the placenta if it is absorbed systemically. Thus, it is recommended to avoid this medicine during pregnancy unless advised by your doctor.

Breast Feeding

Breast Feeding

There is limited information about the effects of Chloramphenicol+Dexamethasone+Polymyxin B on breastfeeding. However, a component of this medicine may pass and appear in the breastmilk. Thus, it is recommended to avoid this medicine while breastfeeding unless advised by your doctor.

Driving

Driving

It is not known whether Chloramphenicol+Dexamethasone+Polymyxin B affects your driving ability or not. Drive if you feel you are alert and comfortable.

Alcohol

Alcohol

Alcohol is not known to interact with Chloramphenicol+Dexamethasone+Polymyxin B. However, avoid using alcohol as it can delay the healing or decrease the body's response to infection.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You do not find any improvement in your condition after using this medicine for 3-4 days.
  • You have a disorder of liver or kidney.
  • You notice any new infections or worsening of your problem.
  • You notice any fungal infection.
  • You should consult your doctor and take oral antibiotics if needed for severe infections.

Mode of Action

How Does It Work?

Chloramphenicol+Dexamethasone+Polymyxin B is a combination of two antibiotics (Polymyxin B and Chloramphenicol) and one steroid medicine (Dexamethasone). Antibiotics kill the bacteria and control infection, while the steroid component of this medicine reduces redness, pain, swelling and discomfort caused due to the infection.

Interactions

Interactions with other medicines

  • Since this medicine is to be used externally on the eyes it is less likely to interact with other medicines. However, you should always consult your doctor if you are taking other medicines for treating other health conditions.
  • Concomitant use of this medicine with atropine or phosphate-containing eye medicines should be done with caution.
  • Medicines such as Phenytoin, Phenobarbitone, Ephedrine and Rifampicin may reduce the effect of this medicine
  • Chloramphenicol+Dexamethasone+Polymyxin B can reduce the action of salicylate medicines.

Dosage

Overdose

  • As Chloramphenicol+Dexamethasone+Polymyxin B is meant for external application, cases of an overdose are unlikely. However, upon accidental ingestion, contact your doctor immediately or visit the nearest hospital.
  • If you have applied extra quantities of it, then wash/wipe out the excess of the medicine with tissue or cotton.

Missed a Dose

If you have missed applying Chloramphenicol+Dexamethasone+Polymyxin B, then apply it as soon as possible. Do not over-apply this medicine just to compensate for the missed application.

Frequently Asked Questions (FAQs)

Chloramphenicol+Dexamethasone+Polymyxin B contains a steroid component, which may increase the pressure of your eyes. You should avoid the use of this medicine if you have glaucoma. Consult your doctor and do not self medicate.

No, Chloramphenicol+Dexamethasone+Polymyxin B should not be used in case of eye ulcers, as it may worsen the condition. Consult your doctor and take proper treatment.

Chloramphenicol+Dexamethasone+Polymyxin B will not cause blindness if used on doctor's advice and in the proper way. However, if it is used for a wrong condition of the eye, which has not been advised by your doctor, it may lead to severe complications.

Do not use this medicine while you are wearing contact lenses. Remove contact lenses before the application of Chloramphenicol+Dexamethasone+Polymyxin B and wait at least 20 minutes or more before reinsertion.

Yes, Chloramphenicol+Dexamethasone+Polymyxin B consists of a combination of two antibiotics which is chloramphenicol & polymyxin B and a steroid called dexamethasone. The combined action of antibiotics and steroids effectively helps in treating eye infections.

The composition of Chloramphenicol+Dexamethasone+Polymyxin B includes a combination of three medicines, polymyxin B, chloramphenicol and dexamethasone.

Itching or burning sensations are a few common side effects of Chloramphenicol+Dexamethasone+Polymyxin B. However, these symptoms are usually mild and resolve with time.

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