Baricitinib
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Molecule Summary
| Uses | Rheumatoid arthritis |
| Therapy | Drugs For Rheumatoid Arthritis |
| Side Effects | Infection, cold sores, nausea, diarrhoea |
Medicines
available
19k pincodes
Molecule Description
Baricitinib is a medicine used for the treatment of rheumatoid arthritis. This medicine works by decreasing immune activity by inhibiting certain enzymes (janus kinase). Rheumatoid arthritis is an auto-immune disorder in which your body mistakenly attacks the healthy cells of the body causing inflammation and pain. It mainly occurs in joints (hands, wrists, and knees) causing pain, lack of balance, tenderness and misshapenness. This medicine relieves pain, swelling and tenderness in joints. The dose and duration of Baricitinib are decided by your doctor after careful assessment of your condition. Take it as advised and inform your doctor about your complete medical history before initiating the treatment.
Uses
For the treatment of rheumatoid arthritis.
Contraindications
When should one not use Baricitinib
- If you are allergic to any component of Baricitinib.
- If you are pregnant or think you may be pregnant.
Side effects
Common side effects of this drug are:
- Throat and nose infections
- Increased cholesterol levels
- Cold sores
- Diarrhoea
- Nausea
- Headache
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
Talk to your doctor if
- You have an infection or you are prone to get infections (weak immune system).
- You experience fever, wounds, feeling more tired than usual or dental problems.
- You have or had tuberculosis, herpes infection or hepatitis B or C.
- You have medical conditions, including kidney or liver problems, low blood cell counts, diabetes, lung disease, HIV.
- You are supposed to take any vaccine.
- You have cancer or liver function problems.
- You have inflammation in your intestine or any stomach problem.
- You have blood clotting disorder or have clots in legs or large veins.
Mode of Action
How Does It Work?
Baricitinib inhibits the enzyme janus kinase. Janus kinase mediates certain inflammatory pathway that leads to tissue damage, inflammation, swelling and pain. By inhibiting this enzyme baricitinib helps relieve pain, tenderness, swelling and discomfort. It also improves movement.
Interactions
Interactions with other medicines
- Certain medicines can affect the way Baricitinib works, or Baricitinib itself can alter the action of other medicines taken along.
- Inform your doctor about all the medicine supplements or herbals you are currently taking or might take to avoid any possible interaction.
- Especially if you are taking medicine for the treatment of gout, medicines for modifying immune response, steroids, medicines for severe pain or inflammation.
Interactions with food items
Baricitinib can be taken with or without food.
Dosage
Overdose
Seek immediate medical advice if you have taken more Baricitinib than you should. Symptoms of an overdose can be similar to its side effects.
Missed a Dose
If you miss a dose, take it as soon as you remember. If you forget your dose for an entire day, just skip the missed dose and take only a single dose as usual the following day. Do not take a double dose to make up for a forgotten dose.
Frequently Asked Questions (FAQs)
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