Artesunate

Molecule Description

Artesunate is an antimalarial agent. It is available as a tablet or an injectio

n (intramuscular or intravenous). It is a critical medicine that is used to treat severe and complicated forms of malaria in children and adults.

Uses

Contraindications

Side effects

Precautions and Warnings

Uses of Artesunate

Artesunate is useful for the treatment of severe malaria caused by a particular species of the malarial parasite - Plasmodium Falciparum.

Contraindications of Artesunate

When should one not use Artesunate

This medicine is not for patients who are allergic to Artesunate or any of its components.

Side effects of Artesunate

Common side effects of this drug are:

Fever
Dizziness, feeling light-headed, headache, sleeping problems, ringing in the ears
Cough, running nose
Decreased hunger, feeling sick (nausea), altered taste, loose motions
Rashes, itching, redness, skin eruptions, hair loss, muscle pains and disorders, fatigue, generalized discomfort, pain at injection site
Heart problems (with high doses)
Allergic reactions, low blood cell counts, liver and pancreas problems

Precautions and Warnings of Artesunate

Pregnancy

Can I take Artesunate during pregnancy?

Artesunate is not recommended for use during the first trimester (first three months) of pregnancy as it can cause new growth defects. It can be used in the second and third trimesters (last six month...
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As Artesunate is used to certain severe, life-threatening forms of malaria, its use should not be withheld in pregnancy if the mother’s life is in danger.

Breast Feeding

Can I take Artesunate while breastfeeding?

Minimal amount of Artesunate secretes in breast milk. It can be given to breastfeeding mothers, but it is recommended to wait for 6 hours after taking Artesunate before feeding breast milk to the baby.

Driving

Can I drive if I have consumed Artesunate?

It is unknown if Artesunate can affect your ability to drive. You may drive if you feel better clinically (feel well and not sick).

Alcohol

Can I consume alcohol with Artesunate?

It is advised to limit your alcohol consumption as Artesunate is used to treat some of the severe forms of malaria, and alcohol may interfere with the process of healing. Mild alcohol consumption is allowed in uncomplicated malaria.

Other General Warnings

Talk to your doctor if

You experience the destruction of red blood cells (post-artmesinin hemolytic anemia) after stopping the treatment is rare but important complication.
A patient who has completed the treatment has to be monitored up to 4 weeks after completion. This condition usually occurs in patients who had a high parasite load.

Mode of Action of Artesunate

How Does It Work?

Artesunate penetrates the red blood cells of the body, which contain the malarial parasite and kills the parasite by interfering with an important enzyme needed for its survival. Artesunate acts rapid...

Interactions of Artesunate

Interactions with other medicines

Artesunate shows enhanced antimalarial action with Mefloquine, Primaquine, and Tetracycline
It has additive effect with Chloroquine
It reduces the impact of Pyrimethamine and Sulfonamides

Interactions with food items

Not much information is available on interactions of Artesunate when taken with food, consult your doctor or pharmacist for further details.

Dietary Restrictions of Artesunate

No information is available on dietary restrictions while you are taking Artesunate, consult your doctor or pharmacist for further details.

Dosage of Artesunate

Overdose

An unintentional overdose of Artesunate may not be harmful. But high overdose can cause seizures (fits), blood in stools, low blood cell counts, and in some cases, may affect multiple organs. Seek imm...

If you are being treated with Artesunate injection, and if you happen to miss the dose, remind your doctor/nurse of the forgotten dose
In case of a tablet, take the missed dose as early as you remember. If your next dose is less than 6 hours away, skip the missed dose, and continue with the next dose as per schedule
Do not take a higher dose or double dose to make up for the missed dose

Frequently Asked Questions (FAQs)

Q: Is there anything else I should know before taking Artesunate?

Generally, Artesunate is administered as an injection and is then switched to tablets.
For the injection, the required dose needs to be calculated carefully based on the weight of the patient. It is better to discuss with the doctor or the pharmacist about the exact dosage and administe...
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The injection is available as a powder in a vial, which is then needed to mix with 1mL of Sodium Bicarbonate solution provided with the package. Wait for some time, like 5-10 minutes.
If the injection is to administer intravenously, mix 5mL of 0.9% Sodium Chloride, and shake the 6mL solution vigorously till the solution is clear. Withdraw this solution with a syringe and should be ...
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In the case of intramuscular injection, mix the original 1mL solution with 2mL of 0.9% Sodium Chloride and shake the resulting 3mL solution vigorously till the solution is clear. Then it should be inj...
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Do not use water to mix with the powder. Use the mixed (reconstituted) solution within 1 hour.

Q: Is Artesunate a safe medicine for Malaria?

Injectable Artesunate is a life-saving medicine that is used to treat severe malaria and is on the essential medicines list of the World Health Organization (WHO). It is also beneficial in traveler’s ...
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This medicine is proved to be a safe medicine with relatively low side effects in both children and adults. It is one of the mainstays of treatment of severe malaria (due to Plasmodium falciparum) in ...
Read more

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Last Updated on: 05 Oct 2020 | 10:47 PM (IST)

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परिचय: “बिना मशरूम के खाना बिना बारिश के दिन जैसा होता है”। मशरूम या अगरिकस बिस्पोरस न तो सब्ज़ी है और न ही फल, बल्कि यह खाई जाने वाली एक फंगस है। बाजार में इसकी अलग-अलग किस्में (ताजा व सूखा) उपलब्ध हैं; जिसमे ओएस्टर , पोर्सिनी और बटन सबसे आम किस्में हैं। आमतौर पर, मशरूम

आंवला (Gooseberry in Hindi) के उपयोग, फ़ायदे और न्यूट्रिशनल वैल्यू

परिचय वानस्पतिक नाम एम्ब्लिका ऑफिसिनैलिस आमतौर पर आंवला को इंडियन गूजबेरी (भारतीय करौंदा) कहा जाता है। इन पेड़ों की बेरी को इनके औषधीय गुणों के कारण औषधीय फार्मूलेशन में प्रयुक्त किया जाता है। आंवला के पेड़ पर छोटी बेरीज़ होती हैं जो गोल और पीले-हरे रंग की होती है। इसके कई स्वास्थ्य फ़ायदों के कारण

केला (Banana in Hindi): उपयोग, लाभ और न्यूट्रिशनल वैल्यू

परिचय: “एक दिन में एक केला (बनाना) खाने से मेरा एंडोर्फिन लेवल बना रहता है।” बनाना (मूसा प्रजाति) या केला एक लंबा, पीला फल है जो वास्तव में एक बेरी है। यह मुसासी (मुसासेई) परिवार से संबंधित हैं और इसमें मूसा एक्यूमिनाटा, मूसा बालबिसियाना आदि किस्में शामिल हैं। यह दक्षिणी एशिया के उष्णकटिबंधीय क्षेत्रों (ट्रॉपिकल

सौंफ (Fennel Seed in Hindi) : उपयोग, लाभ और न्यूट्रिशनल वैल्यू

परिचय: सौंफ (फेनल सीड) का वैज्ञानिक नाम फीनीकुलम वल्गारे है और यह एपोकिनेसी परिवार से संबंधित एक सुगंधित पौधा है।1 सौंफ (फेनल सीड) की एक अलग आकृति, आकार और रंग होता है; यह लंबी, पतली होती है और हल्के हरे या भूरे रंग की होती है। सौंफ (फेनल सीड) का पौधा इसके बीजों, पत्तियों और

ड्रैगन फ्रूट (Dragonfruit in Hindi): उपयोग, लाभ और न्यूट्रिशनल वैल्यू

ड्रैगन फ्रूट कैक्टस प्रजाति का फल होता है जिसके स्वास्थ्य से जुड़े कई लाभ होते हैं जैसे कि रक्त शर्करा (ब्लड शुगर) के जोखिम को कम करना, पाचन (डाइजेशन) में मदद करना आदि। यह एक ड्रैगन की तरह दिखता है और इस वजह से इसका यह नाम पड़ा। अब आप सोच रहे होंगे कि इस

तेजपत्ता (Bay Leaves in Hindi)– उपयोग, फायदे और न्यूट्रिशनल वैल्यू

परिचय तेजपत्ता सिनामोमम तमाला नामक पौधे की सूखी पत्तियां होती हैं। यह सिनामोमम वंश के लौरेसी परिवार का पौधा होता है जिसकी 270 प्रजातियां हैं और प्रमाणिक रूप से ये सभी एशिया और ऑस्ट्रेलिया में पाई जाती हैं। तेजपत्ता को भारतीय बे-लीफ़ भी कहा जाता है जो छोटे सदाबहार या बारहमासी वृक्ष पर होते हैं

नाशपाती (Pear in Hindi): उपयोग, फ़ायदे, न्यूट्रिशनल वैल्यू आदि!

परिचय: नाशपाती का वैज्ञानिक नाम पायरस कमिनिस एल है। यह रोज़ेसी फ़ैमिली से संबंधित है। नाशपाती को सेब के बाद सबसे ज्यादा पौष्टिक फल माना जाता है। यह विटामिन आहार फाइबर, एमिनो एसिड, एवं क्वेरसेटिन का बढ़िया स्रोत होता है। नाशपाती अपने मिठास, सुगंध, कुरकुरेपन और ख़ास खुशबू के लिए जाना जाता है। मूल रूप

सीए 125 टेस्ट (महिलाओं के लिए) (CA 125 Test (For Women) in Hindi): क्या है, खर्च, नॉर्मल रेंज, कैसे होता है, क्यों और कब

विवरण: सीए 125 टेस्ट का इस्तेमाल शरीर में सीए 125 प्रोटीन के स्तर का पता लगाने के लिए किया जाता है, जो कैंसर का पता लगाने में मददगार साबित हो सकता है। नमूना प्रकार खून उपवास \ खाली पेट रहना जरूरी: नहीं उपनाम: कैंसर एंटीजन 125 टेस्ट, सीए-125 ट्यूमर मार्कर, सीए 125 ब्लड टेस्ट। सीए

सीरम इलेक्ट्रोलाइट्स (Serum Electrolytes): क्या है, खर्च, नॉर्मल रेंज, कैसे होता है, क्यों और कब

विवरण: एक सीरम इलेक्ट्रोलाइट परीक्षण आपके खून में मौजूद इलेक्ट्रोलाइट्स के स्तर को मापने की एक विधि है। इससे किडनी या दिल की समस्याओं जैसी कई बीमारियों का निदान करने में मदद मिल सकती है। आपको यह परीक्षण कितनी बार लेना चाहिए? कोई विशिष्ट आवृत्ति नहीं है। डॉक्टर आमतौर पर सीरम इलेक्ट्रोलाइट परीक्षण को मेटाबोलिक

हींग (Asafoetida in Hindi): उपयोग, फ़ायदे, न्यूट्रिशनल वैल्यू और अन्य बातें!

परिचय दुनिया के बहुत से हिस्सों में, हींग (ऐसाफ़ेटिडा) को खाने का स्वाद बढ़ाने वाले तत्व के रूप में और विभिन्न प्रकार की बीमारियों का पारंपरिक रूप से उपचार करने के लिए किया जाता है। हींग (फ़ेरुला ऐसाफ़ेटिडा), एक ओलिओ-गम-रेज़िन है जो अंबेलीफेरा फ़ैमिली के फ़ेरुला पौधों के तनों में बनती है। फ़ेरुला के पौधे

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