Amiodarone

Molecule Description

Amiodarone is a medicine used to treat heart rhythm abnormalities. It belongs t

o a class of medications called ‘antiarrhythmic agents.’

Uses

Contraindications

Side effects

Precautions and Warnings

Uses of Amiodarone

Rhythm disorders of the heart.
Rapid and abnormal heart rhythms (Tachyarrhythmias) that are associated with electrical pathway abnormalities (Wolf-Parkinson-White (WPW syndrome)).
Rapid and regular heartbeats (Atrial Flutter) or fast and irregular heartbeats (Atrial Fibrillation).
Sudden and violent, rapid, abnormal heartbeats (Paroxysmal Tachyarrhythmias), when there are no other alternatives that originate in the ventricles (ventricular), above the ventricles (supraventricula...
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Use with caution.
Medicines that can lengthen heartbeats (Clarithromycin, Ciprofloxacin).
Medicines used for heart diseases and high blood pressure (Propranolol, Diltiazem, Verapamil, Digoxin, Flecainide) for constipation (Bisacodyl, Senna), and to lower cholesterol (Simvastatin, Atorvasta...
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Amphotericin (antifungal), immunosuppressants (Hydrocortisone, Betamethasone, Prednisolone, Cyclosporine, Tacrolimus), anaesthesia medicines (Midazolam, Lidocaine, Fentanyl), Ergotamine (for migraine)...
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Contraindications of Amiodarone

When should one not use Amiodarone

Allergy to Amiodarone or its components or Iodine.
History or signs of severe allergic reactions such as swelling of face, lips, throat, or tongue with swallowing or breathing problems and with or without rashes, itching.
Slow heart rate (Bradycardia), due to blockage of signals from one of the heart nodes (sinoatrial heart block). Nodes are areas in the heart which control heartbeat.
Similar problems with your nodes and you do not have a pacemaker (an artificial device that is used to replace heart nodes).
Past or present thyroid problems.

Side effects of Amiodarone

Common side effects of this drug are:

Jaundice (yellowing of eyes or skin), feeling sick, decreased hunger, pain the stomach, or high temperature (signs of liver damage).
Breathing difficulty, chest tightness, cough, wheeze (whistling sound while breathing), weight loss, fever (signs of lung disease, can be severe).
Irregular or erratic heartbeats (uncommon, but serious) – requires immediate medical attention.
Severe allergic reactions such as swelling of face, lips, throat or tongue with swallowing or breathing problems, even with or without rashes, itching, blistering or peeling of skin, fever, chills, hi...
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Precautions and Warnings of Amiodarone

Pregnancy

Can I take Amiodarone during pregnancy?

Amiodarone is not given during pregnancy as it has the potential to affect the thyroid of the unborn baby.

Breast Feeding

Can I take Amiodarone while breastfeeding?

Do not take if you are breastfeeding or plan to breastfeed; this is because Amiodarone is secreted well into the breast milk and may harm the baby.

Driving

Can I drive if I have consumed Amiodarone?

You can drive while taking Amiodarone. But if you experience any vision problems (Blurry eyesight is one of the side effects of Amiodarone), you are advised not to drive.

Alcohol

Can I consume alcohol with Amiodarone?

Amiodarone is helpful for delicate heart conditions, and alcohol is not suitable for the heart. This medicine should be used with caution if you have any liver problems. Because alcohol also damages the liver and you are advised not to consume alcohol.

Other General Warnings

Talk to your doctor if

Heart, liver, or lung problems (asthma)
Vision problems (including due to damaged optic nerve - optic neuritis)
Elderly patients
Any artificial inserted devices in the heart (pacemaker – which controls heart rate, Implantable Cardioverted Defibrillator (ICD) – a device which detects any abnormal heart rate or rhythm)
Allergic skin reactions

Mode of Action of Amiodarone

How Does It Work?

Balanced potassium levels are mandatory for normal heart rhythm. High potassium levels cause abnormal heart rhythms, which can be fatal. Amiodarone primarily acts by a dual mechanism of reducing potas...

Interactions of Amiodarone

Interactions with other medicines

Medicines used to correct heart rhythm abnormalities (Sotalol, Quinidine, Procainamide, Disopyramide, or Bretylium).
Anti-infectives (injectable Erythromycin, Cotrimoxazole, Moxifloxacin or Pentamidine).
Medicines used to treat mental or behavioural disorders (Thioridazine, Chlorpromazine, Fluphenazine, Haloperidol, Pimozide, Amisulpiride, Lithium, Doxepin, Maprotiline, Sertindole,
or Amitriptyline).
Anti- malarials (Guinine, Mefloquine, Chloroquine or Halofantrine).
Anti-allergics (Terfenadine, Astemizole or Mizolastine).
Hepatitis C medications (Sofosbuvir, Simeprevir, Daclatasvir, or Ledispasvir).

Interactions with food items

Amiodarone does not interact with food, and one can take this medicine before or after meals with a glass of water.

Dietary Restrictions of Amiodarone

Grapefruit juice inhibits the breakdown of Amiodarone in the intestine. It is better to avoid grapefruit and its juice while on Amiodarone.

Dosage of Amiodarone

Overdose

An overdose with Amiodarone can be fatal. Care should be taken to avoid any overdose with this medicine. Overdose symptoms may include weakness, slow heart rate, feeling light-headed, or loss of consc...

Missed a Dose

If you miss a dose of Amiodarone, take it as soon as you remember. However, if it is less than 8 hours for your next dosage, skip the missed dose and follow the regular dosing schedule. Do not take ex...

Q: Amiodarone is a Class III Antiarrhythmic agent. What does this mean?

A: Antiarrhythmic agents are classified into four classes based on their mechanism of action and the targets they act. Class III Antiarrhythmic agents primarily work by decreasing potassium levels and controlling abnormal heart rhythms. Other medicines in this class are Dronedarone, Sotalol, Dofetilide, etc.

Q: What else should I know before taking Amiodarone?

Amiodarone stays in your blood for a long time. It can have some potency and protective action on your heart for up to 1 month after stopping the tablet, this should be remembered, especially if you a...
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Amiodarone can cause skin problems and increases your sensitivity to light.
You are advised to stay away from direct sunlight, use protective clothing and sunscreen lotions during treatment and up to 1 month after stopping Amiodarone.

References

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Last Updated on: 05 Oct 2020 | 10:47 PM (IST)

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एक स्वस्थ जीवन जीने और वज़न कम करने के लिए हम अलग-अलग तरीकों और स्वास्थ्यवर्धक काढ़ों जैसी चीज़ें आज़माते रहते हैं। अनगिनत स्वास्थ्य लाभों का वादा करने के अलावा, ये शरीर को डिटॉक्स करने और वज़न घटाने में मदद करने का भी दावा करते हैं। लेकिन एक पेय (ड्रिंक) है जो ऐसा करने में कामयाब

मशरूम (Mushroom in Hindi) के उपयोग, फ़ायदे, और न्यूट्रिशनल वैल्यू

परिचय: “बिना मशरूम के खाना बिना बारिश के दिन जैसा होता है”। मशरूम या अगरिकस बिस्पोरस न तो सब्ज़ी है और न ही फल, बल्कि यह खाई जाने वाली एक फंगस है। बाजार में इसकी अलग-अलग किस्में (ताजा व सूखा) उपलब्ध हैं; जिसमे ओएस्टर , पोर्सिनी और बटन सबसे आम किस्में हैं। आमतौर पर, मशरूम

आंवला (Gooseberry in Hindi) के उपयोग, फ़ायदे और न्यूट्रिशनल वैल्यू

परिचय वानस्पतिक नाम एम्ब्लिका ऑफिसिनैलिस आमतौर पर आंवला को इंडियन गूजबेरी (भारतीय करौंदा) कहा जाता है। इन पेड़ों की बेरी को इनके औषधीय गुणों के कारण औषधीय फार्मूलेशन में प्रयुक्त किया जाता है। आंवला के पेड़ पर छोटी बेरीज़ होती हैं जो गोल और पीले-हरे रंग की होती है। इसके कई स्वास्थ्य फ़ायदों के कारण

केला (Banana in Hindi): उपयोग, लाभ और न्यूट्रिशनल वैल्यू

परिचय: “एक दिन में एक केला (बनाना) खाने से मेरा एंडोर्फिन लेवल बना रहता है।” बनाना (मूसा प्रजाति) या केला एक लंबा, पीला फल है जो वास्तव में एक बेरी है। यह मुसासी (मुसासेई) परिवार से संबंधित हैं और इसमें मूसा एक्यूमिनाटा, मूसा बालबिसियाना आदि किस्में शामिल हैं। यह दक्षिणी एशिया के उष्णकटिबंधीय क्षेत्रों (ट्रॉपिकल

सौंफ (Fennel Seed in Hindi) : उपयोग, लाभ और न्यूट्रिशनल वैल्यू

परिचय: सौंफ (फेनल सीड) का वैज्ञानिक नाम फीनीकुलम वल्गारे है और यह एपोकिनेसी परिवार से संबंधित एक सुगंधित पौधा है।1 सौंफ (फेनल सीड) की एक अलग आकृति, आकार और रंग होता है; यह लंबी, पतली होती है और हल्के हरे या भूरे रंग की होती है। सौंफ (फेनल सीड) का पौधा इसके बीजों, पत्तियों और

ड्रैगन फ्रूट (Dragonfruit in Hindi): उपयोग, लाभ और न्यूट्रिशनल वैल्यू

ड्रैगन फ्रूट कैक्टस प्रजाति का फल होता है जिसके स्वास्थ्य से जुड़े कई लाभ होते हैं जैसे कि रक्त शर्करा (ब्लड शुगर) के जोखिम को कम करना, पाचन (डाइजेशन) में मदद करना आदि। यह एक ड्रैगन की तरह दिखता है और इस वजह से इसका यह नाम पड़ा। अब आप सोच रहे होंगे कि इस

तेजपत्ता (Bay Leaves in Hindi)– उपयोग, फायदे और न्यूट्रिशनल वैल्यू

परिचय तेजपत्ता सिनामोमम तमाला नामक पौधे की सूखी पत्तियां होती हैं। यह सिनामोमम वंश के लौरेसी परिवार का पौधा होता है जिसकी 270 प्रजातियां हैं और प्रमाणिक रूप से ये सभी एशिया और ऑस्ट्रेलिया में पाई जाती हैं। तेजपत्ता को भारतीय बे-लीफ़ भी कहा जाता है जो छोटे सदाबहार या बारहमासी वृक्ष पर होते हैं

नाशपाती (Pear in Hindi): उपयोग, फ़ायदे, न्यूट्रिशनल वैल्यू आदि!

परिचय: नाशपाती का वैज्ञानिक नाम पायरस कमिनिस एल है। यह रोज़ेसी फ़ैमिली से संबंधित है। नाशपाती को सेब के बाद सबसे ज्यादा पौष्टिक फल माना जाता है। यह विटामिन आहार फाइबर, एमिनो एसिड, एवं क्वेरसेटिन का बढ़िया स्रोत होता है। नाशपाती अपने मिठास, सुगंध, कुरकुरेपन और ख़ास खुशबू के लिए जाना जाता है। मूल रूप

सीए 125 टेस्ट (महिलाओं के लिए) (CA 125 Test (For Women) in Hindi): क्या है, खर्च, नॉर्मल रेंज, कैसे होता है, क्यों और कब

विवरण: सीए 125 टेस्ट का इस्तेमाल शरीर में सीए 125 प्रोटीन के स्तर का पता लगाने के लिए किया जाता है, जो कैंसर का पता लगाने में मददगार साबित हो सकता है। नमूना प्रकार खून उपवास \ खाली पेट रहना जरूरी: नहीं उपनाम: कैंसर एंटीजन 125 टेस्ट, सीए-125 ट्यूमर मार्कर, सीए 125 ब्लड टेस्ट। सीए

सीरम इलेक्ट्रोलाइट्स (Serum Electrolytes): क्या है, खर्च, नॉर्मल रेंज, कैसे होता है, क्यों और कब

विवरण: एक सीरम इलेक्ट्रोलाइट परीक्षण आपके खून में मौजूद इलेक्ट्रोलाइट्स के स्तर को मापने की एक विधि है। इससे किडनी या दिल की समस्याओं जैसी कई बीमारियों का निदान करने में मदद मिल सकती है। आपको यह परीक्षण कितनी बार लेना चाहिए? कोई विशिष्ट आवृत्ति नहीं है। डॉक्टर आमतौर पर सीरम इलेक्ट्रोलाइट परीक्षण को मेटाबोलिक

हींग (Asafoetida in Hindi): उपयोग, फ़ायदे, न्यूट्रिशनल वैल्यू और अन्य बातें!

परिचय दुनिया के बहुत से हिस्सों में, हींग (ऐसाफ़ेटिडा) को खाने का स्वाद बढ़ाने वाले तत्व के रूप में और विभिन्न प्रकार की बीमारियों का पारंपरिक रूप से उपचार करने के लिए किया जाता है। हींग (फ़ेरुला ऐसाफ़ेटिडा), एक ओलिओ-गम-रेज़िन है जो अंबेलीफेरा फ़ैमिली के फ़ेरुला पौधों के तनों में बनती है। फ़ेरुला के पौधे

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