Alpha Lipoic Acid

Molecule Description

Alpha-Lipoic Acid is a vitamin-like supplement that reduces cell damage in the b...
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Uses of Alpha Lipoic Acid

  • Lowering blood glucose levels and treating diabetic nerve pain. By increasing the efficacy of insulin, Alpha-Lipoic Acid will lead to effective glucose control reducing the nerve damage caused by high...
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  • To aid painful bladder syndrome, especially in women. One can also use as an add-on medication to regular treatment. Alpha-lipoic acid will relieve symptoms of painful urination and sex.
  • To improve skin complexion, texture wrinkles, and any damage caused due to sunlight, stress, etc.
  • Alpha-Lipoic acid is also beneficial in metabolic syndrome – disorders of metabolism (processing of food we eat) that lead to problems like diabetes, heart disease, and brain stroke.

Contraindications of Alpha Lipoic Acid

When should one not use Alpha Lipoic Acid

Allergy to Alpha-Lipoic Acid or any components of the medicine.

Side effects of Alpha Lipoic Acid

Common side effects of this drug are:

  • Feeling sick (nausea), vomiting
  • Stomach discomfort, loose motions
  • Rashes
  • Feeling dizzy, spinning of the head (vertigo), psychiatric complaints (mood changes, depression, etc.), anxiety and sleep disturbances (rare)

Precautions and Warnings of Alpha Lipoic Acid



Can I take Alpha Lipoic Acid during pregnancy?
Alpha-Lipoic Acid has proven to be safe during pregnancy even when taken in late stages (up to 37th week). Speak to your doctor if you have to use this medicine during pregnancy.

Breast Feeding

Can I take Alpha Lipoic Acid while breastfeeding?
Enough data is not available, and it is unknown if Alpha-Lipoic Acid secretes in breast milk. Hence it is advised to avoid this medicine during breast-feeding.


Can I drive if I have consumed Alpha Lipoic Acid?
Alpha-Lipoic Acid is not known to affect your driving ability, but experts advise attention in the presence of side effects such as dizziness, spinning of head, sleep disturbances, etc.


Can I consume alcohol with Alpha Lipoic Acid?
Alpha-Lipoic Acid can cause problems if you are suffering from Vitamin B1 (Thiamine) deficiency, as alcohol is known to reduce Vitamin B1 levels in the body. Hence too much alcohol should be avoided. You may take a Thiamine supplement if you have to drink.

Other General Warnings

Talk to your doctor if
Thyroid problems

Mode of Action of Alpha Lipoic Acid

How Does It Work?

Alpha-Lipoic Acid removes or binds harmful substances in the body that damage cells (free radicals). These substances can decrease the efficacy of insulin hormone in the body. Thus, by removing these ...
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Interactions of Alpha Lipoic Acid

Interactions with other medicines

  • Consolidation of Alpha-Lipoic Acid and other medicines that are used to treat diabetes or insulin (like Glimepride, Glipizide, Glyburide, Pioglitazone, Rosiglitazone, Chlorpropamide, Tolbutamide, etc....
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  • Levothyroxine (used to treat hypothyroidism)
  • Anti-cancer medicines

Interactions with food items

Alpha-Lipoic Acid is usually taken 30 minutes before or 2 hours after a meal.

Dietary Restrictions of Alpha Lipoic Acid

Avoid foods or supplements which reduce blood sugar levels while taking Alpha-Lipoic Acid, such as fenugreek, garlic, guar gum, horse chestnut, Panax Ginseng, Psyllium, and Siberian Ginseng.

Dosage of Alpha Lipoic Acid


Alpha-Lipoic Acid causes symptoms of overdosage at very high doses. It may not cause harmful effects at regular or above regular dose. Seek medical attention if you develop symptoms such as rashes, st...
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Missed a Dose

Take the forgotten dose as shortly as you remember. Skip the missed dose if it is too late, do not take extra medicine or double dose to compensate for the missed dose.

Frequently Asked Questions (FAQs)


Q: Does my body produce Alpha-Lipoic Acid?

A: Yes, Alpha-Lipoic Acid is synthesized in our body naturally but in tiny amounts. Rich sources of this supplement include spinach, broccoli, potatoes, rice bran, and peas. Non- vegetarian sources include animal heart, liver and kidneys. Alpha-Lipoic Acid derived from natural sources will not be enough in conditions where there is demand, because the body can generate little of this supplement from foods.

Q: What are the benefits of Alpha-Lipoic Acid?

A: By binding and eliminating the harmful substances (free radicals), Alpha-Lipoic Acid improves the blood flow, functioning of antioxidants (substances that reduce cell damage due to fatty foods, high sugar, alcohol, etc.), and also boost levels of some vitamins and functioning of nerves. Generally, patients who have a problem with their immune system or metabolism or whose immune system is at risk (diabetes, heart disease, infections, stroke, weight gain, skin aging, etc.) will benefit the most from Alpha-Lipoic Acid. A person can take Alpha-lipoic acid for an extended period, but you are advised to discontinue if you start to develop any rashes.
A: In case of heart surgeries, Alpha-Lipoic Acid is started two months before surgery and is to continue until one month after surgery. For weight loss, it is used for a period of two months to one year. You may have to use it continuously in diabetes, but in people with mild and responsive symptoms, treatment for a month will show improvement in symptoms.
Last Updated on: 05 Oct 2020 | 10:47 PM (IST)
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