Indapamide+Amlodipine
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Molecule Summary
| Uses | High blood pressure |
| Therapy | Anti-Hypertensive |
| Side Effects | Dizziness, stomach upset, swelling, headache |
Medicines
available
19k pincodes
Molecule Description
Indapamide+Amlodipine is used to treat hypertension (high blood pressure). It combines two medications, amlodipine and indapamide. It is recommended that Indapamide+Amlodipine be taken with food, preferably in the morning, to reduce the frequency of nocturnal urination. Continue taking this medication for as long as advised by your doctor. Even if you feel well, do not stop taking it on your own, as high blood pressure often has no symptoms. Stopping the medication abruptly could worsen your condition.
Uses
Indapamide+Amlodipine is used to treat high blood pressure.
Contraindications
When should one not use Indapamide+Amlodipine
- If you are allergic to amlodipine, indapamide or any other ingredients of this medicine
- If you have very low blood pressure or heart-related conditions such as stenosis, cardiogenic shock, heart failure after a heart attack.
- If you have an existing kidney failure or liver failure.
- If you have low levels of potassium in your body.
Side effects
Common side effects of this drug are:
- Headache
- Dizziness
- Sleepiness especially at beginning of treatment
- Ankle swelling
- Weakness
- An upset stomach
- Muscle cramps
- Excessive urination
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
Talk to your doctor if
- You have any underlying health condition related to the liver and kidneys.
- You have heart-related conditions or recently had a heart attack or heart failure.
- You are elderly, caution is advised while changing the dose for the elderly.
- You have gout or diabetes.
- You are supposed to do a test to check the parathyroid function.
- You have fluid imbalance or imbalance of sodium or potassium levels in your body.
Mode of Action
How Does It Work?
- Indapamide+Amlodipine contains Amlodipine, a calcium channel blocker that relaxes and widens blood vessels, improving blood flow and reducing resistance for the heart.
- Indapamide is a diuretic that helps the kidneys remove excess salt and water, lowering blood volume and pressure on arterial walls. Together, they effectively control blood pressure and reduce the risk of complications such as strokes or heart attacks.
Interactions
Interactions with other medicines
- Some medicines can affect the way Indapamide+Amlodipine works or Indapamide+Amlodipine itself can reduce the effectiveness of other medicines taken at the same time.
- Tell your doctor about all the medicines, supplements or herbals you are currently taking or might take to avoid any possible interactions.
- Especially, if you are taking medicines such as antibiotics, antifungals, other anti-hypertensive medicines, cholesterol-lowering medicines, medicines for heart conditions and muscle relaxants etc.
- Other medicines that should be used with caution are immunosuppressants, anti-HIV medicines etc.
Interactions with food items
Grapefruit juice and grapefruit should not be consumed along with Indapamide+Amlodipine, as these can cause a drop in your blood pressure.
Dosage
Overdose
Symptoms of an overdose of this medicine include dizziness, lightheadedness, weakness, fast heartbeat or excessive drop in blood pressure etc. Seek immediate medical help in case of an overdose of this medicine.
Missed a Dose
If you have missed taking any dose, take it as soon as you remember if there is sufficient time left for the next scheduled dose. If it is time for the next dose, then skip the missed dose and resume your usual dosing schedule. Do not compensate for the missed dose by taking an extra dose. Missing a dose of this medicine can lead to a rise in blood pressure and should be avoided.
Frequently Asked Questions (FAQs)
Articles
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References:
- Amlodipine 10 mg Tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk.2026 [cited 7 June 2026]
- Şen S, Demir M, Yiğit Z, Üresin A. Efficacy and safety of S-amlodipine 2.5 and 5 mg/d in hypertensive patients who were treatment-naive or previously received antihypertensive monotherapy. J Cardiovasc Pharmacol Ther.[cited 7 Jun 2026]
- Indapamide- Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2026 [cited 7 June 2026]
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