O2 Tablet
10 Tablet(s) in Strip
Product Summary
O2 Tablet, from Medley Pharmaceuticals, combines ofloxacin 200 mg and ornidazole 500 mg to treat diarrhoea and dysentery caused by susceptible mixed bacterial and protozoal infections. This medicine combines antibacterial and antiprotozoal actions. It interferes with microbial DNA processes, stopping susceptible organisms from growing or causing their death.
Medically Reviewed by Dr. Ambika Dashrathrao Mamde
Last updated on: 13 October 2026 | 2:23 PM (IST)
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Dose Form
TABLET
Expiry
General Information
| Therapy | Antibiotic, anti-diarrhoeal |
| Composition | Ofloxacin(200.0 Mg)+Ornidazole(500.0 Mg) Ofloxacin 200.0 Mg+Ornidazole 500.0 Mg |
Ofloxacin 200.0 Mg+Ornidazole 500.0 Mg
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*Offer applicable on orders above ₹1000About O2
O2 tablet is an antibiotic medicine. It is used to treat urinary tract infections, respiratory tract infections, and diarrhea caused by bacteria and parasites, such as amoebas. It is a combination medicine containing ofloxacin and ornidazole as active ingredients. O2 tablet works by killing the bacteria responsible for the infection.
O2 tablets must be taken as prescribed by a doctor. Do not stop taking this medicine if you feel better within a few days. Always finish the course of antibiotic medicine for effective treatment.
You should also be aware that antibiotics are only effective against bacterial infections and not for viral infections like the flu or a cold. Using an antibiotic unnecessarily can make it ineffective for future infections.
Before starting treatment with an O2 tablet, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding, and provide your detailed medical history.
Some other tablets containing ofloxacin and ornidazole are Zenflox Oz, Ornof, Orni O and Nor Metrogyl Plus.
Uses
Contraindications
- If you are allergic to ofloxacin, ornidazole, or any ingredients of the O2 tablet.
- If you are allergic to a specific type of medicine called Fluoroquinolone (ask your doctor or nurse if you are not sure).
- If you have or have had experienced fits or seizures in the past or had epilepsy.
- If you had a swelling and inflammation of tendons (tissues connecting muscles to bones) in the past after use of the same drug or drugs of the same class whose name ends with a suffix -floxacin
- If you are pregnant, planning to have a baby, or breastfeeding.
- Patients with latent or actual defects in glucose-6-phosphate dehydrogenase (G6PD) activity may be prone to haemolytic reactions (leading to destruction of Red Blood Cells and Anemia) when treated with this drug.
Side effects
- Nausea and Vomiting
- Diarrhea
- Abdominal Pain
- Headache
- Anemia
- Kidney and Liver enzyme changes
- Altered taste
- Peripheral neuropathy
Precautions and Warnings
Alcohol
WITH CAUTIONNo major risk with alcohol has been noted; it may increase the risk and worsen the dizziness, so it is advised not to consume alcohol with O2
Pregnancy
CONTRAINDICATEDO2 tablets are not recommended if you are pregnant, think you might be pregnant, or are planning to have a baby, as this medicine may harm your baby. If you conceive while taking this medicine, stop taking this medicine immediately and inform your doctor.
Breastfeeding
CONTRAINDICATEDComponents of O2 tablets is known to pass into human breast milk and can harm your child. Hence, breastfeeding should be discontinued while you are taking this medicine.
Driving
WITH CAUTIONYou may experience sleepiness, dizziness, visual disturbance, poor coordination after taking O2 tablet. It is advisable not to drive if you experience such symptoms.
Other General Warnings
- You developed swelling and pain in tendons (tendonitis) after starting the treatment. You must stop the medicine immediately and contact the doctor.
- You have diabetes and are on insulin or medications for Diabetes. O2 may cause blood glucose to fall. If you start feeling symptoms of hypoglycemia like anxiousness, blurred vision, cold sweats, confusion, rapid heartbeat or tremors then check you blood sugar, consider taking glucose, contact the doctor immediately and stop the O2.
- You have a condition called myasthenia gravis (weakness or fatigue of muscles).
- You experience suicidal thoughts or feel low or anxious, immediately inform your doctor.
- You are having or have a history of a psychotic disorder like schizophrenia
- You experience fits or have a history of fits, seizures or epilepsy.
- You feel restlessness, lightheadedness, confusion or hallucinations.
- You experience allergic reactions, such as fever or rashes.
- You have kidney, liver, or heart problems.
- You have glucose-6-phosphate dehydrogenase deficiency (an inherited disorder that affects red blood cells).
- You have a family history of Long QT syndrome, have low Potassium and Magnesium levels, are elderly, or are taking antidepressants or other drugs that are known to increase the QT interval, you should take O2 cautiously.
- O2 should be used with extreme caution in patients with aortic dissection or heart valve issues, and in patients whose condition predisposes them to dissection and heart valve issues, such as Marfan syndrome, Ehlers-Danlos syndrome, Behçet’s disease, Turner Syndrome, Takayasu arteritis, Giant cell arteritis, or infective endocarditis. The risk is further increased if such people are also on steroids for the management of the above-mentioned conditions.
Directions for use
- Take O2 tablets as directed by your doctor, with or without food. Do not crush, break or chew the tablet. Complete the course of antibiotics for effective infection control.
Storage and disposal
- Store O2 tablet in a cool and dry place, protected from light.
- Keep it out of the reach of children and pets.
Quick tips
- If you start feeling better within a few days, do not stop taking this medication. To ensure effective treatment, always complete the entire course of antibiotics.
- Inform your doctor about your full medical history and whether you are currently breastfeeding, planning pregnancy, or pregnant before starting treatment with an O2 tablet.
- O2 tablets should not be used for tooth infections. They are medications used to treat urinary tract infections, respiratory tract infections, and diarrhea caused by bacteria and parasites like amoebas, in adults only.
- O2 tablets may increase sensitivity to UV radiation. Protect your skin outdoors with sunscreen (SPF 30+) and clothing.
- O2 tablets are not recommended for pregnant or breastfeeding women, children, or adolescents under 18 years old, and should be used cautiously in elderly patients.
Dosage
Overdose
Missed a dose
How O2 works
Interactions
Drug interactions of O2 with other medicine salt
Food interactions
- O2 can be taken with or without food. However, when taken on an empty stomach, the side effect of a metallic taste may be pronounced. O2 tablets should be taken exactly as prescribed by your physician at the recommended time (morning, afternoon, or night).
- It may be taken on an empty stomach before food or after/meal, as advised. Ensure that you adhere to your routine and complete the full course. Your doctor provides the schedule to ensure the medicine works effectively.
Frequently asked questions
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Substitutes for O2
References
- OFLOX-OZ Tablets [Internet]. CiplaMed. 2025 [cited 09th Oct 2025]
- CDSCO [Internet]. Cdscoonline.gov.in. 2025 [cited 09th Oct 2025]
- Ofloxacin [Internet]. Ncbi.nlm.nih.gov. 2025 [cited 09th Oct 2025]
- Ofloxacin 200 mg Tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2025 [cited 09th Oct 2025]
- OFLOXACIN tablet, coated [Internet]. Dailymed.nlm.nih.gov. 2025 [cited 09th Oct 2025]
- MedlinePlus. Ofloxacin: MedlinePlus Drug Information [Internet]. Bethesda (MD): U.S. National Library of Medicine; 2026 [cited 18 May 2026]
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