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O2 Tablet

10 Tablet(s) in Strip
By MEDLEY PHARMACEUTICALS LTD
Salt: Ofloxacin 200.0 Mg+Ornidazole 500.0 Mg
MRP ₹213.95
₹158.32 26% OFF
₹15.83/Tablet (Inclusive of all taxes)
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✱Offer applicable on order above ₹1000
O2 Strip Of 10 Tablets

Product Summary

O2 Tablet, from Medley Pharmaceuticals, combines ofloxacin 200 mg and ornidazole 500 mg to treat diarrhoea and dysentery caused by susceptible mixed bacterial and protozoal infections. This medicine combines antibacterial and antiprotozoal actions. It interferes with microbial DNA processes, stopping susceptible organisms from growing or causing their death.

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General Information

Therapy		 Antibiotic, anti-diarrhoeal
Composition		 Ofloxacin(200.0 Mg)+Ornidazole(500.0 Mg) Ofloxacin 200.0 Mg+Ornidazole 500.0 Mg
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Ofloxacin 200.0 Mg+Ornidazole 500.0 Mg

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About O2

O2 Tablet contains two active ingredients: Ofloxacin and Ornidazole. Ofloxacin is an antibiotic that blocks bacterial enzymes required for bacterial growth and multiplication. Ornidazole is an antimicrobial medicine that acts against certain anaerobic bacteria (bacteria that grow in environments with little or no oxygen) and protozoa (single-celled parasites). Together, these ingredients help treat certain infections caused by susceptible bacteria and protozoa, including some intestinal infections, urinary tract infections, respiratory tract infections, and diarrhea, when prescribed by a doctor.

O2 Tablet is a prescription medicine and should be taken only as directed by your doctor. Complete the prescribed course unless your doctor advises you to stop or change it. Inform your doctor if you have kidney or liver problems, a history of seizures, heart rhythm problems, or if you are pregnant or breastfeeding. Ofloxacin may rarely cause serious side effects involving tendons, nerves or the nervous system. Avoid self-medication and do not take this medicine for every episode of diarrhoea.

Possible side effects include nausea, vomiting, stomach discomfort, diarrhoea, headache, dizziness and a metallic taste in the mouth. Avoid driving or operating machinery if you feel dizzy. Seek medical attention if you develop tendon pain or swelling, numbness or tingling, severe or persistent diarrhoea, or signs of an allergic reaction. If side effects persist or worsen, consult your doctor. If you have diarrhoea, maintain adequate fluid intake to help prevent dehydration.

Some other tablets containing ofloxacin and ornidazole are Zenflox Oz, Ornof, Orni O and Nor Metrogyl Plus.

Uses

O2 tablet is used to treat infections such as urinary tract infections, respiratory tract infections, and diarrhea caused by bacteria and parasites, such as amoebas.

Contraindications

  • If you are allergic to ofloxacin, ornidazole, or any ingredients of the O2 tablet.
  • If you are allergic to a specific type of medicine called Fluoroquinolone (ask your doctor or nurse if you are not sure).
  • If you have or have had experienced fits or seizures in the past or had epilepsy.
  • If you had a swelling and inflammation of tendons (tissues connecting muscles to bones) in the past after use of the same drug or drugs of the same class whose name ends with a suffix -floxacin
  • If you are pregnant, planning to have a baby, or breastfeeding.
  • Patients with latent or actual defects in glucose-6-phosphate dehydrogenase (G6PD) activity may be prone to haemolytic reactions (leading to destruction of Red Blood Cells and Anemia) when treated with this drug.

Side effects

Common
  • Nausea or a metallic taste
  • Loose motions
  • Stomach discomfort
  • Headache or dizziness
  • Loss of appetite
Less common
  • Difficulty sleeping, or vivid dreams
  • Dark urine, which ornidazole can cause and which is harmless
  • A rash or itching
  • Thrush, or a change in vaginal discharge
Seek medical help
  • Pain, swelling or tenderness in a tendon - most often the back of the ankle - or a snapping sensation. Stop the medicine, rest the limb, and contact your doctor. This can happen early and occasionally after the course has finished.
  • New tingling, numbness, burning or weakness in the hands or feet.
  • Confusion, agitation, hallucinations, depression, or thoughts of self-harm.
  • A fit or seizure.
  • Severe or watery diarrhoea, especially with fever or stomach cramps, during or weeks after the course.
  • Severe sunburn or blistering after even brief sun exposure.
  • A fast or irregular heartbeat, or fainting.
  • Swelling of the face, lips or throat, difficulty breathing, or a rash with blistering or peeling.
  • Yellowing of the skin or eyes, or dark urine with pale stools.

Precautions and Warnings

Alcohol

Alcohol

WITH CAUTION

No major risk with alcohol has been noted; it may increase the risk and worsen the dizziness, so it is advised not to consume alcohol with O2

Pregnancy

Pregnancy

CONTRAINDICATED

O2 tablets are not recommended if you are pregnant, think you might be pregnant, or are planning to have a baby, as this medicine may harm your baby. If you conceive while taking this medicine, stop taking this medicine immediately and inform your doctor.

Breast feeding

Breastfeeding

CONTRAINDICATED

Components of O2 tablets is known to pass into human breast milk and can harm your child. Hence, breastfeeding should be discontinued while you are taking this medicine.

Driving

Driving

WITH CAUTION

You may experience sleepiness, dizziness, visual disturbance, poor coordination after taking O2 tablet. It is advisable not to drive if you experience such symptoms.

General warnings

Other General Warnings

Talk to your doctor if
  • You developed swelling and pain in tendons (tendonitis) after starting the treatment. You must stop the medicine immediately and contact the doctor.
  • You have diabetes and are on insulin or medications for Diabetes. O2 may cause blood glucose to fall. If you start feeling symptoms of hypoglycemia like anxiousness, blurred vision, cold sweats, confusion, rapid heartbeat or tremors then check you blood sugar, consider taking glucose, contact the doctor immediately and stop the O2.
  • You have a condition called myasthenia gravis (weakness or fatigue of muscles).
  • You experience suicidal thoughts or feel low or anxious, immediately inform your doctor.
  • You are having or have a history of a psychotic disorder like schizophrenia
  • You experience fits or have a history of fits, seizures or epilepsy.
  • You feel restlessness, lightheadedness, confusion or hallucinations.
  • You experience allergic reactions, such as fever or rashes.
  • You have kidney, liver, or heart problems.
  • You have glucose-6-phosphate dehydrogenase deficiency (an inherited disorder that affects red blood cells).
  • You have a family history of Long QT syndrome, have low Potassium and Magnesium levels, are elderly, or are taking antidepressants or other drugs that are known to increase the QT interval, you should take O2 cautiously.
  • O2 should be used with extreme caution in patients with aortic dissection or heart valve issues, and in patients whose condition predisposes them to dissection and heart valve issues, such as Marfan syndrome, Ehlers-Danlos syndrome, Behçet’s disease, Turner Syndrome, Takayasu arteritis, Giant cell arteritis, or infective endocarditis. The risk is further increased if such people are also on steroids for the management of the above-mentioned conditions.

Directions for use

  • Take O2 tablets as directed by your doctor, with or without food. Do not crush, break or chew the tablet. Complete the course of antibiotics for effective infection control.

Storage and disposal

  • Store O2 tablet in a cool and dry place, protected from light.
  • Keep it out of the reach of children and pets.

Quick tips

  • If you start feeling better within a few days, do not stop taking this medication. To ensure effective treatment, always complete the entire course of antibiotics.
  • Inform your doctor about your full medical history and whether you are currently breastfeeding, planning pregnancy, or pregnant before starting treatment with an O2 tablet.
  • O2 tablets may increase sensitivity to UV radiation. Protect your skin outdoors with sunscreen (SPF 30+) and clothing.
  • O2 tablets are not recommended for pregnant or breastfeeding women, children, or adolescents under 18 years old, and should be used cautiously in elderly patients.
  • Finish the whole course even once you feel better, unless your doctor tells you to stop.
  • No alcohol during the course or for a few days afterwards.
  • Keep milk, curd, antacids and mineral supplements at least two hours away from each dose.
  • Stop and contact your doctor if you have tendon pain or swelling, especially at the back of the ankle, and rest the limb. Avoid strenuous exercise during the course.
  • Stop and seek advice if you develop new tingling, numbness, or weakness in the hands or feet.
  • Tell your doctor about any history of epilepsy, nerve problems, tendon trouble, heart rhythm problems, or mental health conditions before starting.
  • Report severe or watery diarrhoea, even if it starts weeks after the course has finished.

Dosage

Overdose

Symptoms of an overdose of O2 tablets include drowsiness, hot and cold flashes, nausea, dizziness, facial swelling, numbness, slurring of speech and disorientation. In case of an overdose, contact your doctor immediately or visit the nearest hospital.

Missed a dose

If you miss any dose of medicine, take it as soon as you remember. If it's time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one. It is advisable not to miss any dose of antibiotics, as it can result in a failure of therapy.

How O2 works

O2 tablet works by the combined mechanism of its two components. Ofloxacin inhibits the action of enzymes in bacteria responsible for DNA replication, repair, and recombination, thus inhibiting their growth. Ornidazole gets converted into an active form in the body. It interacts with bacterial DNA, inhibits protein synthesis, and leads to cell death.

Interactions

Drug interactions of O2 with other medicine salt

Warfarin

Moderate

O2 tablet can enhance the anticoagulant effects of Warfarin, leading to an increased International Normalized Ratio (INR) and a higher risk of bleeding complications.

Theophylline

Moderate

Ofloxacin may inhibit the metabolism of theophylline, resulting in elevated theophylline blood levels. This can lead to toxicity manifesting as nausea, insomnia, tremors, arrhythmias, or seizures, even when serum levels are only moderately increased.

Cyclosporine

Moderate

Although not extensively studied with ofloxacin, other quinolones have been shown to increase cyclosporine plasma levels, likely by reducing its hepatic metabolism. Elevated cyclosporine levels may predispose patients to nephrotoxicity or hypertension.

Probenecid

Mild

Probenecid may inhibit renal tubular secretion of ofloxacin, potentially increasing its plasma concentration and prolonging systemic exposure. Although the clinical relevance is minimal in most cases, it may increase the risk of dose-related adverse effects, especially in renally impaired patients.

Food interactions

You can take O2 with or without food. However, when taken on an empty stomach, the side effect of a metallic taste may be pronounced. O2 tablets should be taken exactly as prescribed by your physician at the recommended time (morning, afternoon, or night). Take it on an empty stomach before food or after/meal, as advised. Stick to your routine and complete the full course. Your doctor provides the schedule to ensure the medicine works effectively. Do not drink alcohol during the course or for several days after finishing it. Ornidazole belongs to the same family as metronidazole, and the combination can cause flushing, throbbing headache, nausea, vomiting, and palpitations. Leave a gap of at least two hours between this tablet and milk, curd, antacids, or iron, zinc, or calcium supplements. They bind ofloxacin in the gut and prevent absorption, which can make the antibiotic less effective. Drink plenty of water throughout the course. Avoid large amounts of caffeine, which can worsen jitteriness and sleep problems some people experience.

Frequently asked questions

Stop taking O2 tablet and contact your doctor. Fluoroquinolone antibiotics such as ofloxacin can inflame and, in rare cases, rupture a tendon, most often the Achilles at the back of the ankle. The risk is higher in older people, with steroid use, and after a transplant. Rest the limb and avoid strenuous exercise until you have been seen.
Rarely, yes, and this is why the class carries specific warnings. Some people develop tingling, numbness, burning or weakness in the hands or feet, which can persist. Stop and seek advice promptly if that appears rather than finishing the course and hoping it settles.
O2 tablet can make the skin unusually sensitive, so even brief sun exposure may cause burning or a rash. Cover up, use sun protection, and avoid tanning beds while you are taking it.
Ornidazole can darken urine, and that by itself is harmless. Dark urine, along with yellow eyes or skin or pale stools, is different and needs a doctor.
Occasionally. This class of medicine can cause difficulty sleeping, vivid dreams, agitation, confusion, low mood and, rarely, thoughts of self-harm, more often in older people. Tell your doctor promptly if anything like that appears, and seek help the same day for thoughts of self-harm.
Tell your doctor, especially if O2 tablet is severe, watery, or accompanied by fever or cramps. Antibiotics can disrupt gut flora and allow an overgrowth that causes colitis, which can begin weeks after the course ends. Do not simply take an anti-diarrhoeal.
Take this medicine as per your doctor's prescribed duration. Though you may feel better after a few doses, you must complete the course of this antibiotic or the infection may reoccur.
Yes, O2 tablets can interact with other medicines like antacids, multivitamins, cimetidine, warfarin and some antidiabetic medicines.
The daily dose of O2 tablet will be decided by your doctor based on your signs and symptoms. Take this medicine in the exact dose and duration as recommended. Do not take more than the prescribed dose.
Avoid exposure to direct sunlight. Wear a protective covering or use sunscreen (SPF 30 or 40) to prevent sunburn. Avoid dehydration by having plenty of fluids.
No, you should not give this medicine to your child. The O2 tablet should not be used in children below 18 years.
No, O2 tablets should not be used for the treatment of dental infection or any other infection other than what it is prescribed for.
Yes, O2 tablet is used for the treatment of dysentery. Dysentery is an infection of the intestines that causes diarrhoea containing blood or mucus.
You should take O2 tablet exactly as told by the doctor. However, it should preferably be taken with food to avoid a metallic taste. It is advisable to take it at a fixed time to ensure better efficacy.
Take O2 tablets as directed by your doctor, with or without food. Do not crush, break or chew the tablet. Complete the course of antibiotics for effective infection control.
No, O2 tablet is not a painkiller. It is an antibiotic medicine.
O2 Tablet contains ofloxacin and ornidazole. O2H and Oflotas OZ are similar in composition. Norflox TZ contains norfloxacin with tinidazole, and Brakke contains Ofloxacin and Ornidazole. Ciplox 500 contains only ciprofloxacin and is primarily indicated for bacterial infections, not amoebic infections. These medicines differ in ingredients and should not be interchanged without medical advice. Always consult your doctor before using it.
O2 Tablet contains ofloxacin and ornidazole and is mainly used for infectious diarrhea, food poisoning, and intestinal infections caused by bacteria or parasites. It may help when there is infection-related mucus in stool or infective colitis, if prescribed. It is not intended for IBS, hemorrhoids, fistula, throat infection, or tooth pain, unless a physician confirms a specific infection requiring this medication. Misuse can cause side effects and resistance. Always consult your doctor before using it.
O2 Tablet contains ofloxacin and ornidazole and is not recommended for children, as ofloxacin may affect growing joints unless a doctor specifically prescribes it. It should never be given to pets like cats or dogs, because human antibiotics and doses are unsafe for animals. Always consult a doctor or veterinarian before using it.

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Manufacturer Details

Brand: O2

Manufacturer Name: MEDLEY PHARMACEUTICALS LTD

Address: Mediley Pharmaceuticals Ltd., Lane No. 3, Phase-1, Sidco Industrial Complex, Bart Brahmana, Jammu-181 133.

Country of Origin: India

Product Fulfillment

Fulfillment Information: O2 Strip Of 10 Tablets will be delivered by a licensed retail pharmacy nearest to your location. Order acceptance and fulfillment are dependent upon the verification of your doctor's valid prescription (where applicable) and the current stock of this medicine.

In Case of Any Issues Contact Us

Email Id: care@pharmeasy.in

Phone Number: 7666100300

Address: D-37/1, Opp. Sandoz, TTC Industrial Area, MIDC Industrial Area, Turbhe, Navi Mumbai, Maharashtra 400703

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The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please visit to detailed T&C.

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